KaydedilenlerDerginizi ekleyin

Dergiler / Turkish Journal of Medical Sciences / 2014 / Cilt: 44 - Sayı: 2

Relationship of admission neutrophil-to-lymphocyte ratio with in-hospital mortality in patients with acute type I aortic dissection

Ömer Faruk ÇİÇEK
Hacı Alper UZUN
Adnan YALÇINKAYA
İrfan TAŞOĞLU
Gökhan LAFÇI
Orhan Eren GÜNERTEM
Kemal KORKMAZ
Hikmet Selçuk GEDİK
Kerim ÇAĞLI
Kumral ÇAĞLI
Osman TURAK
Adem İlkay DİKEN
Sayfa
186–192
Yayın Tarihi
2022-11-05
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Conclusion: This study suggests that admission neutrophil-to-lymphocyte ratio is a potential predictive parameter for determining the in-hospital mortality of acute type I aortic dissection.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Aim: Acute aortic dissection is a life-threatening cardiovascular emergency.
📊
Temel Bulgular & Veri:Materials and methods: We retrospectively evaluated 123 consecutive patients who had undergone emergent surgery for acute type I aortic dissection.
💡
Sonuç & Katkı:Conclusion: This study suggests that admission neutrophil-to-lymphocyte ratio is a potential predictive parameter for determining the in-hospital mortality of acute type I aortic dissection.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Aim: Acute aortic dissection is a life-threatening cardiovascular emergency. Neutrophil-to-lymphocyte ratio is proposed as a prognostic marker and found to be related to worse clinical outcomes in various cardiovascular diseases. The aim of the present study was to evaluate the relationship between admission neutrophil-to-lymphocyte ratio and in-hospital mortality in acute type I aortic dissection. Materials and methods: We retrospectively evaluated 123 consecutive patients who had undergone emergent surgery for acute type I aortic dissection. Patients were divided into 2 groups as patients dying in the hospital (Group 1) and those discharged alive (Group 2). All parameters, including neutrophil-to-lymphocyte ratio, were compared between the 2 groups and predictors of mortality was estimated by using multivariate analysis. Results: A total of 104 patients (79 males, mean age: 55.2 ± 14 years) were included in the final analysis. In multivariate analyses, crossclamp time, cardiopulmonary bypass time, intensive care unit duration, platelet count, and neutrophil-to-lymphocyte ratio were found to be independent predictors of mortality. Patients with higher neutrophil-to-lymphocyte ratios had a significantly higher mortality rate (hazard ratio: 1.05; 95% CI: 1.01 1.10; P = 0.033). Receiver operating characteristic analysis revealed that using a cut-off point of 8, neutrophil-to-lymphocyte ratio predicts mortality with a sensitivity of 70% and specificity of 53%. Conclusion: This study suggests that admission neutrophil-to-lymphocyte ratio is a potential predictive parameter for determining the in-hospital mortality of acute type I aortic dissection.

🔖

Bu Makaleye Atıf Yap

ÇİÇEK, Ö. F., UZUN, H. A., YALÇINKAYA, A., TAŞOĞLU, İ., LAFÇI, G., GÜNERTEM, O. E., KORKMAZ, K., GEDİK, H. S., ÇAĞLI, K., ÇAĞLI, K., TURAK, O., DİKEN, A. İ. (2022). Relationship of admission neutrophil-to-lymphocyte ratio with in-hospital mortality in patients with acute type I aortic dissection. Turkish Journal of Medical Sciences, Cilt: 44 - Sayı: 2, 186–192. https://ajindex.com/articles/611009

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (11)

  1. Mészáros I, Mórocz J, Szlávi J, Schmidt J, Tornóci L, Nagy L, Szép L. Epidemiology and clinicopathology of aortic dissection. Chest 2000; 117: 1271–1278
  2. Erbel R, Alfonso F, Boileau C, Dirsch O, Eber B, Haverich A, Rakowski H, Struyven J, Radegran K, Sechtem U et al. Diagnosis and management of aortic dissection. Eur Heart J 2001; 22: 1642–1681
  3. Rampoldi V, Trimarchi S, Eagle KA, Nienaber CA, Oh JK, Bossone E, Myrmel T, Sangiorgi GM, De Vincentiis C, Cooper JV et al. Simple risk models to predict surgical mortality in acute type A aortic dissection: the international registry of acute aortic dissection score. Ann Thorac Surg 2007; 83: 55–61. 4. del Porto F, Proietta M, Tritapepe L, Miraldi F, Koverech A, Cardelli P, Tabacco F, de Santis V, Vecchione A, Mitterhofer AP et al. Inflammation and immune response in acute aortic dissection. Ann Med 2010; 42: 622–629
  4. Luo F, Zhou XL, Li JJ, Hui RT. Inflammatory response is associated with aortic dissection. Ageing Res Rev 2009; 8: 31– 35
  5. Schillinger M, Domanovits H, Bayegan K, Hölzenbein T, Grabenwöger M, Thoenissen J, Röggla M, Müllner M. C-reactive protein and mortality in patients with acute aortic disease. Intens Care Med 2002; 28: 740–745
  6. Ranasinghe AM, Bonser RS. Biomarkers in acute aortic dissection and other aortic syndromes. J Am Coll Cardiol 2010; 56: 1535–1541
  7. AlMahameed ST, Novaro GM, Asher CR, Hougthaling PL, Lago RM, Bhatt DL, AlMahameed AT, Topol EJ. Predictive value of high sensitivity C-reactive protein in the diagnosis and outcomes of acute aortic syndromes. Heart Asia 2010; 2: 136–139
  8. Sakakura K, Kubo N, Ako J, Wada H, Fujiwara N, Funayama H, Ikeda N, Nakamura T, Sugawara Y, Yasu T et al. Peak C-reactive protein level predicts long-term outcomes in type b acute aortic dissection. Hypertension 2010; 55: 422–429
  9. Okina N, Ohuchida M, Takeuchi T, Fujiyama T, Satoh A, Sakamoto T, Adachi H, Imaizumi T. Utility of measuring C-reactive protein for prediction of in-hospital events in patients with acute aortic dissection. Heart Vessels 2013; 28: 330–335
  10. Duffy BK, Gurm HS, Rajagopal V, Gupta R, Ellis SG, Bhatt DL. Usefulness of an elevated neutrophil to lymphocyte ratio in predicting long-term mortality after percutaneous coronary intervention. Am J Cardiol 2006; 97: 993–996
  11. Spark JI, Sarveswaran J, Blest N, Charalabidis P, Asthana S. An elevated neutrophil-lymphocyte ratio independently predicts mortality in chronic critical limb ischemia. J Vasc Surg 2010; 52: