KaydedilenlerDerginizi ekleyin

Dergiler / Turkish Journal of Medical Sciences / 2016 / Cilt: 46 - Sayı: 4

Emergency department visits caused by adverse drug reactions: results of a Turkish university hospital

Yeşim TUNÇOK
Mualla Aylin ARICI
Özgür DOYLAN
Mehmet Can GİRGİN
Yücel DEMİRAL
Sedat YANTURALI
Neşe ÇOLAK ORAY
Sayfa
945–952
Yayın Tarihi
2022-11-05
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Multicenter epidemiologic studies are required to know the real rates of ADR cases in EDs in Turkey

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Background/aim: We aimed to evaluate adverse drug reaction (ADR)-related emergency department (ED) visits in the ED of the Dokuz Eylül University Hospital prospectively.
📊
Temel Bulgular & Veri:Materials and methods: Patients who were admitted to the ED during 1-week periods of four different seasons between July 2010 and April 2011 were enrolled.
💡
Sonuç & Katkı:Multicenter epidemiologic studies are required to know the real rates of ADR cases in EDs in Turkey
🔬Tür:Araştırma Makalesi
📍Kapsam:2010 Verileri
⚙️Değişkenler:Alan Parametreleri

Abstract

Background/aim: We aimed to evaluate adverse drug reaction (ADR)-related emergency department (ED) visits in the ED of the Dokuz Eylül University Hospital prospectively. Materials and methods: Patients who were admitted to the ED during 1-week periods of four different seasons between July 2010 and April 2011 were enrolled. Demographics of patients, previous ADR history, clinical progress, and outcomes were recorded. Causality assessment was done according to World Health Organization Uppsala Monitoring Centre categories. ADRs were categorized as certain, probable, or possible. Results: Patients who were on medications (26.5%, n = 1838) were evaluated for ADR-related ED admissions. ADRs accounted for 5.9% of cases (n = 108). The most frequently affected systems were the gastrointestinal (35.2%, n = 38), dermatological (23.1%, n = 25), and hematological (10.2%, n = 11) systems (7.4%, n = 8). The most common causes of ADRs were antiinfectives (31.6%, n = 33). Amoxicillin, Coumadin, and paracetamol were the most common medications that caused ADRs. Conclusion: Nearly 6% of the admissions were ADR-related. ADRs should always be considered when patients who are on medication are admitted to the ED. Multicenter epidemiologic studies are required to know the real rates of ADR cases in EDs in Turkey

🔖

Bu Makaleye Atıf Yap

TUNÇOK, Y., ARICI, M. A., DOYLAN, Ö., GİRGİN, M. C., DEMİRAL, Y., YANTURALI, S., ORAY, N. Ç. (2022). Emergency department visits caused by adverse drug reactions: results of a Turkish university hospital. Turkish Journal of Medical Sciences, Cilt: 46 - Sayı: 4, 945–952. https://ajindex.com/articles/610766

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (14)

  1. Edwards IR, Aronson JK. Adverse drug reactions: definitions, diagnosis, and management. Lancet 2000; 356: 1255-1259
  2. Wu TY, Jen MH, Bottle A, Molokhia M, Aylin P, Bell D, Majeed A. Ten-year trends in hospital admissions for adverse drug reactions in England 1999-2009. J R Soc Med 2010; 103: 239- 250
  3. Rehan HS, Chopra D, Kakkar AK. Physician’s guide to pharmacovigilance: terminology and causality assessment. Eur J Intern Med 2009; 20: 3-8
  4. Capuano A, Irpino A, Gallo M, Ferrante L, Illiano ML, Rinaldi B, Filippelli A, Rossi F. Regional surveillance of emergencydepartment visits for outpatient adverse drug events. Eur J Clin Pharmacol 2009; 65: 721-728
  5. Patel KJ, Kedia MS, Bajpai D, Mehta SS, Kshirsagar NA, Gogtay NJ. Evaluation of the prevalence and economic burden of adverse drug reactions presenting to the medical emergency department of a tertiary referral centre: a prospective study. BMC Clin Pharmacol 2007; 7: 8
  6. De Paepe P, Petrovic M, Outtier L, Van Maele G, Buylaert W. Drug interactions and adverse drug reactions in the older patients admitted to the emergency department. Acta Clin Belg 2013; 68: 15-21
  7. Queneau P, Bannwarth B, Carpentier F, Guliana JM, Bouget J, Trombert B, Leverve X, Lapostolle F, Borron SW, Adnet F et al. Emergency department visits caused by adverse drug events: results of a French survey. Drug Saf 2007; 30: 81-88
  8. Wilbur K, Hazi H, El-Bedawi A. Drug-related hospital visits and admissions associated with laboratory or physiologic abnormalities-a systematic-review. PLoS One 2013; 27; 8: e66803
  9. Lazarou J, Pomeranz BH, Corey PN. Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. JAMA 1998; 279: 1200-1205
  10. Üstünes L, editor. RxMediaPharma İnteraktif İlaç Bilgi Kaynağı. İzmir, Turkey: GEMAŞ; 2011
  11. Klasco RK, editor. DRUGDEX® System. Greenwood Village, CO, USA: Thomson Micromedex (Vol. 149 expires 09/2011)
  12. Ma J, Wang Y, Gao M, Meng Q, Liu J. Adverse drug reactions as the cause of emergency department admission of patients aged 80 years and older. Eur J Intern Med 2012; 23: e162-163
  13. Roulet L, Asseray N, Dary M, Chiffoleau A, Potel G, Ballereau F. Implementing a clinical pharmacy survey of adverse drug events in a French emergency department. Int J Clin Pharm 2012; 34: 902-910
  14. Chen YC, Fan JS, Hsu TF, Chen MH, Huang HH, Cheng KW, Yen DH, Huang MS, Lee CH, Chen LK et al. Detection of patients presenting with adverse drug events in the emer