Yapay Zeka Hızlı Bakış & Çıkarımlar
AI InsightPositive samplesfrom screening tests should be tested with AHG if the SWT value is
📌 3 Maddede Bu Makale
Abstract
Background/aim: It was aimed to evaluate the results of Rose Bengal (RB), ELISA total tests (IgM and IgG), and the Brucella Coombsgel test (BCGT), which are used as screening tests, with the combined results of a tube agglutination test (standard Wright test: SWT)and a tube agglutination test with antihuman globulin (AHG TAT).Materials and methods: Samples from 97 patients prediagnosed with brucellosis (age ≥18 years) were screened with RB, ELISA, andBCGT. SWT < 160 samples and RB-negative but ELISA- or BCGT-positive samples were tested by AHG TAT. SWT ≥ 160 or AHG TAT≥ 160 was taken as reference.Results: Thirty-two of 56 RB-positive samples and one RB-negative but ELISA- and BCGT-positive sample were found to be ≥160with SWT or AHG TAT. Sensitivity, specificity, accuracy, and agreement (kappa) values according to SWT ≥ 160 or AHG TAT ≥ 160positivity were as follows, respectively: RB 96.9%, 62.5%, 74.2%, and 0.509; ELISA total 100%, 60.9%, 74.2%, and 0.515; BCGT test 97%,70.3%, 79.4%, and 0.594.Conclusion: Sensitivities of the screening tests are similar, but positivities should be confirmed by more specific tests. Positive samplesfrom screening tests should be tested with AHG if the SWT value is