When TG levels before and after TPE were evaluated,the mean TG level before TPE was significantly higher (3132 ± 1472 mg/dL) than the mean TG level afterwards (948 ± 465 mg/dL, P
📌 3 Maddede Bu Makale
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Amaç & Hipotez:Background/aim: High triglyceride (TG) levels are associated with increases in atherosclerotic cardiovascular disease (CVD), hepaticsteatosis, and pancreatitis.
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Temel Bulgular & Veri:In this study, the results of TPE were evaluatedand the frequency of lipoprotein lipase (LPL) mutation in these patients was determined.Materials and methods: TPE was performed in 31 patients with HTGP at the Adult Therapeutic Apheresis Center.Results: A TG level under 500 mg/dL was achieved by applying apheresis at a median of 2 times (IQR 2–2, min 1, max 6) in the 31 cases.LPL mutation was detected in 8 (25.8%) of the 31 hypertriglyceridemia cases.
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Sonuç & Katkı:When TG levels before and after TPE were evaluated,the mean TG level before TPE was significantly higher (3132 ± 1472 mg/dL) than the mean TG level afterwards (948 ± 465 mg/dL, P
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri
Abstract
Background/aim: High triglyceride (TG) levels are associated with increases in atherosclerotic cardiovascular disease (CVD), hepaticsteatosis, and pancreatitis. Acute pancreatitis is a condition with high mortality. Therapeutic plasma exchange (TPE) in the treatmentof hypertriglyceridemic pancreatitis (HTGP) is a rapid and effective treatment modality. In this study, the results of TPE were evaluatedand the frequency of lipoprotein lipase (LPL) mutation in these patients was determined.Materials and methods: TPE was performed in 31 patients with HTGP at the Adult Therapeutic Apheresis Center.Results: A TG level under 500 mg/dL was achieved by applying apheresis at a median of 2 times (IQR 2–2, min 1, max 6) in the 31 cases.LPL mutation was detected in 8 (25.8%) of the 31 hypertriglyceridemia cases. When TG levels before and after TPE were evaluated,the mean TG level before TPE was significantly higher (3132 ± 1472 mg/dL) than the mean TG level afterwards (948 ± 465 mg/dL, P
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Bu Makaleye Atıf Yap
ERDOĞAN, M., ŞİMŞİR, I. Y., SOYALTIN, U. E., YÜREKLİ, B. S., DÖNMEZ, A., SAYGILI, F., ÖZGEN, A. G., ÇETİNKALP, Ş. (2022). Therapeutic plasma exchange in hypertriglyceridemic patients. Turkish Journal of Medical Sciences, Cilt: 49 - Sayı: 3, 872–878. https://ajindex.com/articles/610085
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