Dergiler / Turkish Journal of Medical Sciences / 2020 / Cilt: 50 - Sayı: 4

Evaluation of the cardioprotective effects of crystalloid del Nido cardioplegia solution via a rapid and accurate cardiac marker: heart-type fatty acid-binding protein

Sayfa
999–1006
Yayın Tarihi
2022-11-05
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Preoperative and postoperative levels of cardiac enzymes including CK-MB, troponin I and H-FABP were comparable in delNido solution and cold blood cardioplegia solution groups.Conclusion: According to these results, when we compare both demographic data and CK-MB, troponin I and H-FABP levels, bothcardioplegia solutions were comparable regarding safety and efficacy in terms of myocardial protection.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Background/aim: Our aim in this study was to compare the efficacy and safety of crystalloid del Nido solution and cold bloodcardioplegia solution on clinical and laboratory parameters.Materials and methods: Sixty patients who underwent elective coronary bypass operation between July 2019 and January 2020 wereincluded in our study.
📊
Temel Bulgular & Veri:Patients were divided into 2 groups of 30 patients using del Nido solution (DNS) and cold blood cardioplegiasolution (CBCS), which were given for cardiac arrest.
💡
Sonuç & Katkı:Preoperative and postoperative levels of cardiac enzymes including CK-MB, troponin I and H-FABP were comparable in delNido solution and cold blood cardioplegia solution groups.Conclusion: According to these results, when we compare both demographic data and CK-MB, troponin I and H-FABP levels, bothcardioplegia solutions were comparable regarding safety and efficacy in terms of myocardial protection.
🔬Tür:Araştırma Makalesi
📍Kapsam:2019 Verileri
⚙️Değişkenler:Alan Parametreleri

Abstract

Background/aim: Our aim in this study was to compare the efficacy and safety of crystalloid del Nido solution and cold bloodcardioplegia solution on clinical and laboratory parameters.Materials and methods: Sixty patients who underwent elective coronary bypass operation between July 2019 and January 2020 wereincluded in our study. Patients were divided into 2 groups of 30 patients using del Nido solution (DNS) and cold blood cardioplegiasolution (CBCS), which were given for cardiac arrest. Demographic data, preoperative, postoperative 0th h, 6th h and 4th day creatinekinase myocardial band (CK-MB) and troponin I values were compared with a specific cardiac enzyme heart-type fatty acid-bindingprotein (H-FABP).Results: We found that aortic cross clamp duration and cardiopulmonary bypass (CPB) time were shorter in patients using del Nidosolution than cold blood cardioplegia solution (57.30 ± 23.57 min, 76.07 ± 27.18 min, P = 0.006) (95.07 ± 23.06 min, 114.13 ± 33.93, P =0.014). Total cardioplegia solution volume was higher in the cold blood cardioplegia solution group (1426.67 ± 416.00 vs. 1200 ± 310.73P = 0.02). Preoperative and postoperative levels of cardiac enzymes including CK-MB, troponin I and H-FABP were comparable in delNido solution and cold blood cardioplegia solution groups.Conclusion: According to these results, when we compare both demographic data and CK-MB, troponin I and H-FABP levels, bothcardioplegia solutions were comparable regarding safety and efficacy in terms of myocardial protection.

🔖

Bu Makaleye Atıf Yap

AYKAN, D. A., KOÇARSLAN, A., DOĞANER, A., ORAK, Y., KİRİŞCİ, M., BAYLAN, F. A. (2022). Evaluation of the cardioprotective effects of crystalloid del Nido cardioplegia solution via a rapid and accurate cardiac marker: heart-type fatty acid-binding protein. Turkish Journal of Medical Sciences, Cilt: 50 - Sayı: 4, 999–1006. https://ajindex.com/articles/609833

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (4)

  1. Roe BB, Hutchinson JC, Fishman NH, Ullyot DJ, Smith DL. Myocardial protection with cold, ischemic, potassium-induced cardioplegia. The Journal of Thoracic and Cardiovascular Surgery 1977; 73 (3): 366-374
  2. Conti VR, Bertranou EG, Blackstone EH, Kirklin JW, Digerness SB. Cold cardioplegia versus hypothermia for myocardial protection. Randomized clinical study. The Journal of Thoracic and Cardiovascular Surgery 1978; 76 (5): 577-589
  3. Melrose DG, Dreyer B, Bentall HH, Baker JB. Elective cardiac arrest. Lancet 1955; 269: 21-22. doi: 10.1016/S0140- 6736(55)93381-X 4. Matte GS, Del Nido PJ. History and use of del Nido cardioplegia solution at Boston Children’s Hospital. The Journal of ExtraCorporeal Technology 2012; 44: 98-103
  4. Bojan M, Peperstraete H, Lilot M, Tourneur L, Vouhé P et al. Cold histidine-tryptophan-ketoglutarate solution and repeated oxygenated warm blood cardioplegia in neonates with arterial switch operation. The Annals of Thoracic Surgery 2013; 95 (4): 1390-1396. doi: 10.1016/j.athoracsur.2012.12.025 6. Yerebakan H, Sorabella RA, Najjar M, Castillero E, Mongero L et al. Del Nido cardioplegia can be safely administered in high-risk coronary artery bypass grafting surgery after acute myocardial infarction: a propensity matched comparison. Journal of Cardiothoracic Surgery 2014; 9: 141. doi: 10.1186/ s13019-014-0141-5 7. Timek T, Willekes C, Hulme O, Himelhoch B, Nadeau D et al. Propensity matched analysis of del Nido cardioplegia in adult coronary artery bypass grafting: initial experience with 100 consecutive patients. The Annals of Thoracic Surgery 2016; 101 (6): 2237-2241. doi: 10.1016/j.athoracsur.2015.12.058 8. Smigla G, Jaquiss R, Walczak R, Bonadonna D, Kaemmer D et al. Assessing the safety of del Nido cardioplegia solution in adult congenital cases. Perfusion 2014; 29 (6): 554-558. doi: 10.1177/0267659114543346 9. Ota T, Yerebakan H, Neely RC, Mongero L, George I et al. Short-term outcomes in adult cardiac surgery in the use of del Nido cardioplegia solution. Perfusion 2016; 31 (1): 27-33. doi: 10.1177/0267659115599453 10. Mick SL, Robich MP, Houghtaling PL, Gillinov AM, Soltesz EG et al. Del Nido versus Buckberg cardioplegia in adult isolated valve surgery. The Journal of Thoracic and Cardiovascular Surgery 2015; 149 (2): 626-636.e5. doi: 10.1016/j. jtcvs.2014.10.085 11. Guajardo Salinas GE, Nutt R, Rodriguez-Araujo G. Del Nido cardioplegia in low risk adults undergoing first time coronary artery bypass surgery. Perfusion 2017