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Dergiler / Turkish Journal of Botany / 2019 / Cilt: 43 - Sayı: 2

G-Quadruplex enrichment analysis reveals their role as intronic regulatory elements in plants

Osman DOLUCA
Sayfa
151–166
Yayın Tarihi
2022-11-03
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

The results indicate that G-quadruplex distribution has gone through significant changes with the evolution of higherplants and, for the first time, that G-quadruplexes enriched at the beginning of introns may have a regulatory role during transcription.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:G-Quadruplexes, a class of noncanonical but highly stable nucleic acid structures, have the potential to be part of theregulatory mechanism of cells.
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Temel Bulgular & Veri:They can form in the genome where the double-stranded helix is unwound to facilitate formation of aG-quadruplex.
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Sonuç & Katkı:The results indicate that G-quadruplex distribution has gone through significant changes with the evolution of higherplants and, for the first time, that G-quadruplexes enriched at the beginning of introns may have a regulatory role during transcription.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

G-Quadruplexes, a class of noncanonical but highly stable nucleic acid structures, have the potential to be part of theregulatory mechanism of cells. They can form in the genome where the double-stranded helix is unwound to facilitate formation of aG-quadruplex. The biological significance of these structures is yet to be understood entirely. This work presents a novel approach andinvestigates common characteristics in the distribution of G-quadruplexes relative to genes in plants through analysis of genomes andgene expressions. The results indicate that G-quadruplex distribution has gone through significant changes with the evolution of higherplants and, for the first time, that G-quadruplexes enriched at the beginning of introns may have a regulatory role during transcription.

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Bu Makaleye Atıf Yap

DOLUCA, O. (2022). G-Quadruplex enrichment analysis reveals their role as intronic regulatory elements in plants. Turkish Journal of Botany, Cilt: 43 - Sayı: 2, 151–166. https://ajindex.com/articles/600844

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Kaynakça (5)

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