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Dergiler / Southern Clinics of Istanbul Eurasia / 2020 / Cilt: 31 - Sayı: 4

Methemoglobinemia in Two Infants Brought to the Pediatric Emergency Department

Öner ÖZDEMİR
Ayşegül PALA
Olena ERKUN
Zahir ŞEHMUSOĞLU
Sayfa
397–400
Yayın Tarihi
2022-10-19
DOI
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Yapay Zeka Hızlı Bakış & Çıkarımlar

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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

This case report is a presentation of the diagnosis and treatment of prilocaine-induced methemoglobinemia in 2 recently circumcised infants admitted to the pediatric emergency department.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Methemoglobinemia is a complication that develops when ferrous hemoglobin is oxidized to a ferric state.
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Temel Bulgular & Veri:Methemoglobinemia is characterized by cyanosis when the blood level exceeds 10%, and at higher levels it may cause tissue hypoxemia, coma, cardiovascular collapse, or even death.
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Sonuç & Katkı:This case report is a presentation of the diagnosis and treatment of prilocaine-induced methemoglobinemia in 2 recently circumcised infants admitted to the pediatric emergency department.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Methemoglobinemia is a complication that develops when ferrous hemoglobin is oxidized to a ferric state. It may be congenital due to structural hemoglobin defects or acquired through causes such as exposure to local anesthetic drugs or intake of toxins. Methemoglobinemia is characterized by cyanosis when the blood level exceeds 10%, and at higher levels it may cause tissue hypoxemia, coma, cardiovascular collapse, or even death. The primary mechanism used to reduce the methemoglobin level in the body is the nicotinamide adenine dinucleotide phosphate-cytochrome b5 reductase pathway. This case report is a presentation of the diagnosis and treatment of prilocaine-induced methemoglobinemia in 2 recently circumcised infants admitted to the pediatric emergency department.

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Bu Makaleye Atıf Yap

ÖZDEMİR, Ö., PALA, A., ERKUN, O., ŞEHMUSOĞLU, Z. (2022). Methemoglobinemia in Two Infants Brought to the Pediatric Emergency Department. Southern Clinics of Istanbul Eurasia, Cilt: 31 - Sayı: 4, 397–400. https://ajindex.com/articles/592763

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Kaynakça (10)

  1. Caner İ, Ziraatçı Ö, Taştekin A. Methemoglobinemia due to prilocaine which treated with oral methylene blue. Çocuk Hast Derg 2011;5:172−6
  2. Mansouri A. Methemoglobinemia. Am J Med Sci 1985;289:200−9
  3. Hjelt K, Lund JT, Scherling B, Bendixen S, Lundstrøm K, Støvring S, et al. Methaemoglobinaemia among neonates in a neonatal intensive care unit. Acta Paediatr 1995;84:365−70
  4. Svecova D, Bohmer D. Congenital and acquired methemoglobinemia and its therapy. Cas Lek Cesk 1988;137:168−70
  5. Kara A, Yiğit S, Aygun C. Toxic methemoglobinemia after injection of prilocaine in a newborn case report. Turk J Pediatr 1998;40:589−92
  6. Coleman MD, Coleman NA. Drug induced methemoglobinemia. Drug Safety 1996;14:394−405
  7. Shamriz O, Cohen-Glickman I, Reif S, Shteyer E. Methemoglobinemia induced by lidocaine-prilocaine cream. Isr Med Assoc J 2014;16:250−4
  8. Wright RO, Lewander WJ, Woolf AD. Methemoglo-binemia: Etiology, Pharmacology, and Clinical Management. Ann Emerg Med 1999;34:646−6.1
  9. Aydoğan M, Gedikbaşı T, Türker G. Prilokaine bağlı toksik methemoglobinemide intravenöz askorbik asit kullanımı. Çocuk Sağlığı ve Hastalıkları Dergisi 2005;48:65−8
  10. Prchal JT, Gregg XT. Red cell enzymes. Hematology Am Soc Hematol Educ Program 2005:19−23.