Hereby, we tried to emphasize someanti-cytokine drug and treatment modalities for COVID-19 patients.
📌 3 Maddede Bu Makale
🎯
Amaç & Hipotez:Cytokine storm has been proposed as the basis of the pathophysiological process of COVID-19 causedby SARS-CoV-2.
📊
Temel Bulgular & Veri:For this reason, manytreatment options that have been tried before have been applied for COVID-19 patients as well.
💡
Sonuç & Katkı:Hereby, we tried to emphasize someanti-cytokine drug and treatment modalities for COVID-19 patients.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri
Abstract
Cytokine storm has been proposed as the basis of the pathophysiological process of COVID-19 causedby SARS-CoV-2. Cytokine storm, generally known as excessive or uncontrolled release of especially proinflammatory cytokines, occurs due to several infectious and non-infectious causes. For this reason, manytreatment options that have been tried before have been applied for COVID-19 patients as well. Althoughthere is not a proven treatment so far, there are some promising agents. Hereby, we tried to emphasize someanti-cytokine drug and treatment modalities for COVID-19 patients.
🔖
Bu Makaleye Atıf Yap
TOPELİ, A., HALAÇLI, B. (2022). Treatment of the Cytokine Storm in COVID-19. Journal of critical and intensive care (Online), Cilt: 11 - Sayı: 1, 36–40. https://ajindex.com/articles/562308
Norelli M, Camisa B, Barbiera G, et al. Monocyte-derived IL-1 and IL-6 are differentially required for cytokine-release syndrome and neurotoxicity due to CAR T cells. Nat Med. 2018; 24 (6): 739‐48
Chen L, Liu HG, Liu W, et al. [Analysis of clinical features of 29 patients with 2019 novel coronavirus pneumonia]. Zhonghua jie he he hu xi za zhi = Zhonghua Jiehe he Huxi Zazhi = Chinese Journal of Tuberculosis and Respiratory Diseases. 2020 Feb; 43 (0): E005
Sun X, Wang T, Cai D, et al. Cytokine storm intervention in the early stages of COVID-19 pneumonia [published online ahead of print, 2020 Apr 25]. Cytokine Growth Factor Rev. 2020; S1359-6101 (20) 30048-4
La Rosée P, Horne A, Hines M, et al. Recommendations for the management of hemophagocytic lymphohistiocytosis in adults. Blood. 2019; 133 (23): 2465‐77
Halacli B, Unver N, Halacli SO, et al. Investigation of hemophagocytic lymphohistiocytosis in severe sepsis patients. J Crit Care. 2016; 35: 185‐90
Henter JI, Horne A, Arico ́ M, et al. HLH-2004: diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer. 2007; 48 (2): 124-31 11. Fardet L, Galicier L, Lambotte O, et al. Development and validation of the H Score, a score for the diagnosis of reactive hemophagocytic syndrome. Arthritis Rheumatol. 2014; 66 (9): 2613–20
Alijotas-Reig J, Esteve-Valverde E, Belizna C, et al. Immunomodulatory therapy for the management of severe COVID-19. Beyond the antiviral therapy: A comprehensive review. Autoimmun Rev. 2020; 102569
Henderson LA, Canna SW, Schulert GS, et al. On the Alert for Cytokine Storm: Immunopathology in COVID-19. Arthritis Rheumatol. 2020; 10.1002/art.41285
Zhang W, Zhao Y, Zhang F, et al. The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from China. Clin Immunol. 2020; 214: 108393