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Dergiler / Journal of Clinical and Analytical Medicine / 2016 / Cilt: 7 - Sayı: 5

Farklı Yaş Gruplarında AMH ve FSH Arasındaki Diskordans Oranları

Discordance Rates Between AMH and FSH in Different Age Groups

Belgin DEVRANOGLU
Seracettin GÜNAYDIN
Enis ÖZKAYA
Selçuk SELÇUK
Mehmet KÜÇÜKBAŞ
Melda KUYUCU
Hüseyin Tayfun KUTLU
Sayfa
621–624
Yayın Tarihi
2022-10-18
DOI
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Data from our study and the literature lead us to conclude that age-based AMH and FSH levels and also that discordance between these parameters may vary among different ethnic groups

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Amaç & Hipotez:Aim: To evaluate the discordance rates between anti-Müllerian hormone (AMH) and follicle stimulating hormone (FSH) levels according to different age groups in a cohort of Turkish women.
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Temel Bulgular & Veri:Patients were divided into 4 groups as = 40 years to evaluate the discordance between AMH and FSH in terms of age.
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Sonuç & Katkı:Data from our study and the literature lead us to conclude that age-based AMH and FSH levels and also that discordance between these parameters may vary among different ethnic groups
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Aim: To evaluate the discordance rates between anti-Müllerian hormone (AMH) and follicle stimulating hormone (FSH) levels according to different age groups in a cohort of Turkish women. Material and Method: This retrospective study was conducted at infertility clinics of Zeynep Kamil Training and Research Hospital. Patients were divided into 4 groups as = 40 years to evaluate the discordance between AMH and FSH in terms of age. Discordance rates, and median level of AMH and of FSH were determined for each age group. Results: 467 patients who met the inclusion criteria were enrolled in the study. 35.1% (n=164), 28.3% (n=132), 22.7%(n=106), and 13.9% (n=65) of patients were = 40 years, respectively. The discordance rates in terms of normal AMH but abnormal FSH level were 4.2%, 6.7%, 11.0%, 17.9% in the =40 years age groups, respectively, whereas the discordance rates in terms of normal FSH but abnormal AMH levels were 6.2%, 8.5%, 16.7%, 17.9% in the same age groups, respectively. Discussion: Discordance rates steadily increased with advancing age both for concerning AMH-reassuring FSH and concerning FSH-reassuring AMH. Data from our study and the literature lead us to conclude that age-based AMH and FSH levels and also that discordance between these parameters may vary among different ethnic groups

Abstract

Amaç: Farklı yaş gruplarına göre anti-Müllerian hormon (AMH) ve folikül stimülan hormon (FSH) arasındaki diskordans oranının Türk kadın kohortunda araştırılması. Gereç ve Yöntem: Bu retrospektif çalışma, Zeynep Kamil Eğitim Araştırma Hastanesi infertilite kliniğinde gerçekleştirildi. Hastalar; yaş gruplarına göre AMH ve FSH arasındaki diskordansı değerlendirmek amacıyla = 40 yaş olmak üzere dört gruba ayrıldı. Diskordans oranı, AMH ve FSH median değerleri yaş gruplarına göre incelendi. Bulgular: Çalışmaya dahil edilme kriterlerini sağlayan 467 hasta çalışmaya dahil edildi. Hastaların %35.1'i (n=164) =40 yaş idi. Diskordans oranı normal AMH-anormal FSH değeri olan hastalar için =40 yaş hasta grupları için sırasıyla %4.2, %6.7, %11.0, %17.9 olarak saptandı. Normal FSH-anormal AMH değeri olan hastalarda diskordans oranı =40 yaş hasta grupları için sırasıyla %6.2, %8.5, %16.7, %17.9 olarak tespit edildi. Tartışma: Diskordans oranının normal AMH-anormal FSH değeri olan ve anormal AMH-normal FSH değeri olan Çalışmamızın sonuçları ve literatürdeki sonuçlara göre farklı etnik gruplarda AMH ve FSH arasındaki diskordans oranlarının ve yaşa göre AMH ve FSH düzeylerinin farklılık gösterebileceği düşünülmektedir.

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Bu Makaleye Atıf Yap

DEVRANOGLU, B., GÜNAYDIN, S., ÖZKAYA, E., SELÇUK, S., KÜÇÜKBAŞ, M., KUYUCU, M., KUTLU, H. T. (2022). Farklı Yaş Gruplarında AMH ve FSH Arasındaki Diskordans Oranları. Journal of Clinical and Analytical Medicine, Cilt: 7 - Sayı: 5, 621–624. https://ajindex.com/articles/560925

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Kaynakça (13)

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