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Dergiler / Journal of Basic and Clinical Health Sciences / 2020 / Cilt: 4 - Sayı: 2

Are There Any Sex-Depended Differences in Water Transporting Proteins of Choroid Plexus in Mice?

Berna SÖZEN
Necdet DEMİR
Bikem SÜZEN
Güneş AYTAÇ
Gamze TANRIÖVER
Sayfa
123–127
Yayın Tarihi
2022-10-19
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Conclusion: In conclusion, to the best of our knowledge, AQP2 expression was shown in the CP for the first time, and no sex hormonedependent differences were found in terms of expressions of AQP1, 2 and 4.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Background: It is known that sex hormones show modulatory effects on the central nervous system (CNS).
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Temel Bulgular & Veri:Various CNS pathologies show sex-related differences in terms of rates, symptoms, and the course of the disease.
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Sonuç & Katkı:Conclusion: In conclusion, to the best of our knowledge, AQP2 expression was shown in the CP for the first time, and no sex hormonedependent differences were found in terms of expressions of AQP1, 2 and 4.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Background: It is known that sex hormones show modulatory effects on the central nervous system (CNS). Various CNS pathologies show sex-related differences in terms of rates, symptoms, and the course of the disease. Some of the functions of choroid plexus (CP) are under the control of sex hormones. The aim of this descriptive study was to evaluate sex effects on CP water channels. Methods: Expressions of Aquaporin (AQP) 1, 2 and 4 proteins in CP were compared between in male and female Balb/C mice brains; and also in different stages of the estrous cycle, with immunohistochemistry. Results: No difference is observed for AQP 1, 2 and 4 immunoreactivities in male and female brain, including different stages of the estrous cycle. Conclusion: In conclusion, to the best of our knowledge, AQP2 expression was shown in the CP for the first time, and no sex hormonedependent differences were found in terms of expressions of AQP1, 2 and 4.

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Bu Makaleye Atıf Yap

SÖZEN, B., DEMİR, N., SÜZEN, B., AYTAÇ, G., TANRIÖVER, G. (2022). Are There Any Sex-Depended Differences in Water Transporting Proteins of Choroid Plexus in Mice?. Journal of Basic and Clinical Health Sciences, Cilt: 4 - Sayı: 2, 123–127. https://ajindex.com/articles/560580

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Kaynakça (16)

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