KaydedilenlerDerginizi ekleyin

Dergiler / İstanbul Kuzey Klinikleri / 2017 / Cilt: 4 - Sayı: 2

A comparison of the effectiveness of amitriptilin and pregabalin treatment in fibromyalgia patients

Arzu KAYA
Semra AKTURK
Gurkan AKGOL
Gunseli ACET
Sayfa
151–159
Yayın Tarihi
2022-10-18
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Pain at all tender points was measured using a pressure algometer.RESULTS: Significant improvement was observed in both groups after 12 weeks of treatment (p

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:OBJECTIVE: The present study is a comparison of the effectiveness of amitriptyline and pregabalin on the symptoms of fibromyalgia patients.METHODS: A total of 71 female patients aged >=18 years were included in this study.
📊
Temel Bulgular & Veri:The patients were divided into 2 groups.
💡
Sonuç & Katkı:Pain at all tender points was measured using a pressure algometer.RESULTS: Significant improvement was observed in both groups after 12 weeks of treatment (p
🔬Tür:Uygulamalı Anket & Alan Araştırması
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

OBJECTIVE: The present study is a comparison of the effectiveness of amitriptyline and pregabalin on the symptoms of fibromyalgia patients.METHODS: A total of 71 female patients aged >=18 years were included in this study. The patients were divided into 2 groups. Pregabalin (n=36) or amitriptyline (n=35) treatment was initiated at daily oral dose of 450 mg and 25 mg, respectively for the indicated number of patients. The patients were evaluated at the start of treatment and at the end of 12 weeks. The Fibromyalgia Impact Questionnaire, Fatigue Severity Scale, Modified Fatigue Impact Scale, Hospital Anxiety Depression Scale, Nottingham Health Profile, Mini Mental State Test, and the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) were administered to all study participants. Pain at all tender points was measured using a pressure algometer.RESULTS: Significant improvement was observed in both groups after 12 weeks of treatment (p

🔖

Bu Makaleye Atıf Yap

KAYA, A., AKTURK, S., AKGOL, G., ACET, G. (2022). A comparison of the effectiveness of amitriptilin and pregabalin treatment in fibromyalgia patients. İstanbul Kuzey Klinikleri, Cilt: 4 - Sayı: 2, 151–159. https://ajindex.com/articles/551605

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (16)

  1. Koçanoğulları H. Fibromiyalji sendromu. Gümüşdiş G, Doğanavşargil E, editors. Klinik Romatoloji. İstanbul: Deniz Press; 1999. p. 549-54
  2. Branco JC, Bannwarth B, Failde I, Abello Carbonell J, Blotman F, Spaeth M, et al. Prevalence of fibromyalgia: a survey in five European countries. Semin Arthritis Rheum 2010;39:448-53
  3. Yunus MB. Towards a model of pathophysiology of fibromyalgia: aberrant central pain mechanisms with peripheral modulation. J Rheumatol 1992;19:846-50
  4. Reisine S, Fifield J, Walsh SJ, Feinn R. Do employment and family work affect the health status of women with fibromyalgia? J Rheumatol 2003;30:2045-53
  5. Moldofsky H, Scarisbrick P, England R, Smythe H. Musculosketal symptoms and non-REM sleep disturbance in patients with "fibrositis syndrome" and healthy subjects. Psychosom Med 1975;37:341-51
  6. Gür A. Etiopathogenesis in Fibromyalgia. Turk J Phys Med Rehab 2008:54 Suppl 1;4-11
  7. Reynolds MD. Clinical diagnosis of psychogenic rheumatism. West J Med 1978;128:285-90
  8. White KP, Nielson WR, Harth M, Ostbye T, Speechley M. Chronic widespread musculoskeletal pain with or without fibromyalgia: psychological distress in a representative community adult sample. J Rheumatol 2002;29:588-94
  9. Russell IJ, Orr MD, Littman B, Vipraio GA, Alboukrek D, Michalek JE, et al. Elevated cerebrospinal fluid levels of substance P in patients with the fibromyalgia syndrome. Arthritis Rheum 1994;37:1593-601
  10. Özgöçmen S, Ardıçoğlu Ö. Pharmacotherapy in fibromyalgia syndrome. Syndrome 2000;12:84-8
  11. Lee YH, Song GG. Comparative efficacy and tolerability of duloxetine, pregabalin, and milnacipran for the treatment of fibromyalgia: a Bayesian network meta-analysis of randomized controlled trials. Rheumatol Int 2016;36:663-72
  12. Bennet RM. The Fibromyalgia Syndrome. In: Kelley WN. Harris ED Jr. Ruddy S. Sledge C, editors. Textbook of Rheumatology. Philadelphia: WB Saunders Company; 1997. p. 471-9
  13. Patkar AA, Masand PS, Krulewicz S, Mannelli P, Peindl K, Beebe KL, et al. A randomized, controlled, trial of controlled release paroxetine in fibromyalgia. Am J Med 2007;120:448-54
  14. Frank B, Niesler B, Bondy B, Späth M, Pongratz DE, Ackenheil M, et al. Mutational analysis of serotonin receptor genes: HTR3A and HTR3B in fibromyalgia patients. Clin Rheumatol 2004;23:338-44
  15. White KP, Harth M. Classification, epidemiology, and natural history of fibromyalgia. Curr Pain Headache Rep 2001;5:320- 9
  16. Crofford LJ, Rowbotham MC, Mease PJ, Rus