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Dergiler / İstanbul Kuzey Klinikleri / 2017 / Cilt: 4 - Sayı: 3

Using terlipressin in a pediatric patient with septic shock resistant to catecholamines

Seher ERDOGAN
Mehmet BOSNAK
Sayfa
283–287
Yayın Tarihi
2022-10-18
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

The goal in presenting this case was to evaluate the vasoconstrictor effects of TP, a long-acting vasopressin analogue, in septic shock.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Sepsis and septic shock are important causes of morbidity and mortality in critically ill children.
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Temel Bulgular & Veri:A 14-year-old boy had septic shock, with a high cardiac index and low systemic vascular resistance index (SVRI) measurements according to pulse contour analysis, despite treatment with dopamine, dobutamine, adrenaline, and noradrenaline infusions.
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Sonuç & Katkı:The goal in presenting this case was to evaluate the vasoconstrictor effects of TP, a long-acting vasopressin analogue, in septic shock.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Sepsis and septic shock are important causes of morbidity and mortality in critically ill children. The goal of treatment is to ensure adequate mean arterial pressure to maintain organ perfusion. The growing number of instances of peripheral vascular hyporeactivity to catecholamines has necessitated the search for alternative vasopressors. A 14-year-old boy had septic shock, with a high cardiac index and low systemic vascular resistance index (SVRI) measurements according to pulse contour analysis, despite treatment with dopamine, dobutamine, adrenaline, and noradrenaline infusions. A terlipressin (TP) 10 ?g/kg intravenous bolus was administered, followed by a 1 ?g/kg/minute continuous infusion. The response to TP treatment was assessed using pulse contour analysis. The mean arterial pressure and SVRI increased, and the cardiac index and heart rate decreased within 10 minutes after bolus administration of TP. Noradrenaline infusion could be reduced to 0.7 ?g/kg/minute within 5 hours. The goal in presenting this case was to evaluate the vasoconstrictor effects of TP, a long-acting vasopressin analogue, in septic shock.

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Bu Makaleye Atıf Yap

ERDOGAN, S., BOSNAK, M. (2022). Using terlipressin in a pediatric patient with septic shock resistant to catecholamines. İstanbul Kuzey Klinikleri, Cilt: 4 - Sayı: 3, 283–287. https://ajindex.com/articles/551576

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Kaynakça (14)

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