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Dergiler / İstanbul Kuzey Klinikleri / 2017 / Cilt: 4 - Sayı: 1

Association between serum vitamin B12 level and frailty in older adults

Pinar SOYSAL
Ahmet Turan ISİK
Ozge DOKUZLAR
Sayfa
22–28
Yayın Tarihi
2022-10-18
DOI
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When the 3 groups were compared, it was found that patients in frail group had highest average age and lowest education level (p

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Amaç & Hipotez:OBJECTIVE: Frailty is associated with recurrent falls, fractures, limitation of daily living activities, cognitive impairment, increase in hospitalization, placement in nursing home, and mortality rate in older adults.
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Temel Bulgular & Veri:The aim of this study was to investigate association between frailty and vitamin B12, which has been demonstrated to be related to numerous geriatric syndromes.METHODS: Total of 335 patients who presented at geriatric outpatient clinic and underwent comprehensive geriatric assessment were included in this study.
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Sonuç & Katkı:When the 3 groups were compared, it was found that patients in frail group had highest average age and lowest education level (p
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

OBJECTIVE: Frailty is associated with recurrent falls, fractures, limitation of daily living activities, cognitive impairment, increase in hospitalization, placement in nursing home, and mortality rate in older adults. Although malnutrition is one of the most important etiological factors, role of micronutrients is unclear. The aim of this study was to investigate association between frailty and vitamin B12, which has been demonstrated to be related to numerous geriatric syndromes.METHODS: Total of 335 patients who presented at geriatric outpatient clinic and underwent comprehensive geriatric assessment were included in this study. All patients were evaluated with both Fatigue, Resistance, Ambulation, Illnesses, and Loss of Weight (FRAIL) scale and Fried criteria for frailty. Vitamin B12 deficiency was defined as serum vitamin B12 level of less than 400 pg/mL.RESULTS: In total of 335 patients, 88 (26.3%) were assessed as frail, 156 (46.6%) were prefrail, and 91 (27.2%) were robust. When the 3 groups were compared, it was found that patients in frail group had highest average age and lowest education level (p

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Bu Makaleye Atıf Yap

SOYSAL, P., ISİK, A. T., DOKUZLAR, O. (2022). Association between serum vitamin B12 level and frailty in older adults. İstanbul Kuzey Klinikleri, Cilt: 4 - Sayı: 1, 22–28. https://ajindex.com/articles/551568

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Kaynakça (14)

  1. Morley JE, Vellas B, van Kan GA, Anker SD, Bauer JM, Bernabei R, et al. Frailty consensus: a call to action. J Am Med Dir Assoc 2013;14:392-7
  2. Soysal P, Stubbs B, Lucato P, Luchini C, Solmi M, Peluso R, et al. Inflammation and frailty in the elderly: A systematic review and meta-analysis. Ageing Res Rev 2016;31:1-8
  3. Vermeiren S, Vella-Azzopardi R, Beckwée D, Habbig AK, Scafoglieri A, Jansen B, et al; Gerontopole Brussels Study group. Frailty and the Prediction of Negative Health Outcomes: A Meta-Analysis. J Am Med Dir Assoc 2016;17:1163.e1-1163.e17
  4. Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, et al. Cardiovascular Health Study Collaborative Research Group. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci 2001;56:M146-56
  5. Walston JD. Connecting Age-Related Biological Decline to Frailty and Late-Life Vulnerability. Nestle Nutr Inst Workshop Ser 2015;83:1-10
  6. Bonnefoy M, Berrut G, Lesourd B, Ferry M, Gilbert T, Guérin O, et al. Frailty and nutrition: searching for evidence. J Nutr Health Aging 2015;19:250-7 7. Goisser S, Guyonnet S, Volkert D. The Role of Nutrition in Frailty: An Overview. J Frailty Aging 2016;5:74-7
  7. Bozoglu E, Isik AT, Doruk H, Kilic S. e e ects of early vitamin B12 replacement therapy on the cognitive and functional status of elderly subjects. Klinik Psikofarmakoloji Bülteni 2010;20:120-4
  8. Michelon E, Blaum C, Semba RD, Xue QL, Ricks MO, Fried LP. Vitamin and carotenoid status in older women: associations with the frailty syndrome. J Gerontol A Biol Sci Med Sci 2006;61:600-7
  9. Wahlqvist ML, Saviage GS. Interventions aimed at dietary and lifestyle changes to promote healthy aging. Eur J Clin Nutr 2000;54 Suppl 3:S148-56
  10. Soysal P, Isik AT, Buyukaydin B, Kazancioglu R. A comparison of end-stage renal disease and Alzheimer's disease in the elderly through a comprehensive geriatric assessment. Int Urol Nephrol 2014;46:1627-32
  11. Babacan-Yildiz G, Isik AT, Ur E, Aydemir E, Ertas C, Cebi M, et al. COST: Cognitive State Test, a brief screening battery for Alzheimer disease in illiterate and literate patients. Int Psychogeriatr 2013;25:403-12
  12. Işık AT, Soysal P. Geriatri Pratiğinde Ölçekler. İstanbul Tıp Kitabevleri: İstanbul; 2016
  13. Woo J, Leung J, Morley JE. Comparison of frailty indicators based on clinical phenotype and the multiple deficit approach in predicting mortality and physical limitation. J Am Geriatr Soc 2012;60:1478-86
  14. Trevisan C, Ver