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Dergiler / İstanbul Kuzey Klinikleri / 2021 / Cilt: 8 - Sayı: 6

Drug-induced anaphylaxis in the emergency department: A prospective observational study

Fatma Sari DOĞAN
Vehbi OZAYDIN
Sayfa
595–600
Yayın Tarihi
2022-10-18
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

The reasons underlying this approach should be investigated.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:OBJECTIVE: Anaphylaxis is an acute, life-threatening, systemic hypersensitivity reaction.
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Temel Bulgular & Veri:METHODS: Patients over 18 years old who were diagnosed drug-induced anaphylaxis in the Goztepe Hospital within a period of 1 year were evaluated prospectively.
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Sonuç & Katkı:The reasons underlying this approach should be investigated.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

OBJECTIVE: Anaphylaxis is an acute, life-threatening, systemic hypersensitivity reaction. It is usually triggered by drugs, foods, and insect stings. The primary objective of our study is to determine the factors affecting drug-induced anaphylaxis to contribute to early diagnosis and treatment in these patients. METHODS: Patients over 18 years old who were diagnosed drug-induced anaphylaxis in the Goztepe Hospital within a period of 1 year were evaluated prospectively. Patients demographical data, etiological factors, clinical findings, and treatment information were recorded. RESULTS: Forty-four patients were enrolled in the study of which 25 (56.8%) were female. The median age of women and men was 54 (min: 22, max 82) and 44 (min 18, max 82), respectively. Twenty-three (52%) of them had a history of anaphylaxis. The most common causes of drug-induced anaphylaxis were antibiotics (36%) and nonsteroidal anti-inflammatory drugs (18%), respectively. Adrenaline was applied to 17 (38%) of the patients in the treatment. CONCLUSION: Antibiotics were the most common drugs causing drug-induced anaphylaxis and adrenaline was underused which is the first-line treatment in the anaphylaxis. Some clinicians refrain from administering adrenaline. The reasons underlying this approach should be investigated.

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Bu Makaleye Atıf Yap

DOĞAN, F. S., OZAYDIN, V. (2022). Drug-induced anaphylaxis in the emergency department: A prospective observational study. İstanbul Kuzey Klinikleri, Cilt: 8 - Sayı: 6, 595–600. https://ajindex.com/articles/551238

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Kaynakça (13)

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