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Dergiler / İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi / 2017 / Cilt: 24 - Sayı: 4

Is mean platelet volume a predictor of atherosclerosis in hemodialysis patients?

Baris ESER
Mehmet Deniz AYLİ
Ozlem YAYAR
Fahrettin BİCAKCİ
Sayfa
430–433
Yayın Tarihi
2022-10-17
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

The patients havinghigher MPV values were found to have higher PTH (533.9 ± 458.3 vs 845.8 ± 860.2; P

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Aim: Cardiovascular (CV) mortality accounts for the 45% of all mortality in dialysis.
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Temel Bulgular & Veri:The aim of this study is to determine the relation of MPV with CIMT in haemodialysis (HD) patients without a history of atherosclerosis.Material and Methods: Eighty two HD patients and 20 healthy individuals were enrolled in this cross-sectional study.
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Sonuç & Katkı:The patients havinghigher MPV values were found to have higher PTH (533.9 ± 458.3 vs 845.8 ± 860.2; P
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Aim: Cardiovascular (CV) mortality accounts for the 45% of all mortality in dialysis. Carotid intima-media thickness (CIMT) is aIs mean platelet volume a predictor of atherosclerosis inhemodialysis patients? preclinical marker for CV disease. Activated platelets pose important part of the cellular component in the pathophysiology of atherothrombosis. Mean platelet volume (MPV) is a parameter that indicates the activation of platelets and assessed by studies in various patient groups in atherosclerosis. The aim of this study is to determine the relation of MPV with CIMT in haemodialysis (HD) patients without a history of atherosclerosis.Material and Methods: Eighty two HD patients and 20 healthy individuals were enrolled in this cross-sectional study. UltrasonographicalB-mode imaging of bilateral carotid arteries was performed with a high resolution real-time ultrasonography with 12MHz linear- assay transducer (Mindray DC7). The value was expressed as an average of the maximal CIMT. MPV was measured by automated devices.Results: CIMT was found to be higher in study population when compared to control group. MPV was not different between groups(8.40±0.85 vs 8.4±0.81; P>0.05). In correlation analysis CIMT was found to be positively correlated with age(r=0.326; P=0.003),ALP(r=0.309; P=0.005) and MPV(r=0.26; p= 0,017). Patients were grouped according to median levels of MPV. The patients havinghigher MPV values were found to have higher PTH (533.9 ± 458.3 vs 845.8 ± 860.2; P

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Bu Makaleye Atıf Yap

ESER, B., AYLİ, M. D., YAYAR, O., BİCAKCİ, F. (2022). Is mean platelet volume a predictor of atherosclerosis in hemodialysis patients?. İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi, Cilt: 24 - Sayı: 4, 430–433. https://ajindex.com/articles/549143

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Kaynakça (13)

  1. Bal Z, Bal U, Okyay K, Yilmaz M, Balcioglu S, Turgay O, et al. Hematological parameters can predict the extent of coronary artery disease in patients with end‐stage renal disease. Int Urol Nephrol 2015;47(10):1719-25.
  2. Henning BF, Zidek W, Linder B, Tepel M. Mean platelet volume and coronary heart disease in hemodialysis patients. Kidney Blood Press Res 2002;25(2):103-8.
  3. Ju HY, Kim JK, Hur SM, Woo SA, Park KA, Park MY, et al. Could mean platelet volume be a promising biomarker of progression of chronic kidney disease? Platelets 2015;26(2):143-7.
  4. Turgutalp K, Özhan O, Akbay E, Tombak A, Tiftik N, Ozcan T, et al. Mean platelet volume and related factors in patients at different stages of diabetic nephropathy: a preliminary study. Clin Appl Thromb Hemost 2014;20(2):190-5.
  5. Papanas N, Symeonidis G, Maltezos E, Mavridis G, Karavageli E, Vosnakidis T, et al. Mean platelet volume in patients with type 2 diabetes mellitus. Platelets 2004;15(8):475-8.
  6. Yüksel KG, Gür M, Baykan AO, Uçar H, Elbasan Z, Şahin DY, et al. Mean platelet volume is associated with aortic intima- media thickness in patients without clinical manifestation of atherosclerotic cardiovascular disease. Anatol J Cardiol 2015;15(9):753-8
  7. Mayer FJ, Hoke M, Schillinger M, Minar E, Arbesú I, Koppensteiner R, et al. Mean platelet volume predicts outcome in patients with asymptomatic carotid artery disease. Eur J Clin Invest 2014;44(1):22-8.
  8. Abalı G, Akpınar O, Söylemez N. Correlation of the coronary severity scores and mean platelet volume in diabetes mellitus. Adv Ther 2014;31(1):140-8.
  9. Ma H, Lin H, Hu Y, Li X, He W, Jin X, et al. Mean platelet volume in relation to carotid atherosclerosis in normotensive, euglycemic, and normolipidemic chinese middle-aged and elderly adults. Angiology 2014;65(6):512-8.
  10. Berger JS, Eraso LH, Xie D, Sha D, Mohler ER 3rd. Mean platelet volume and prevalence of peripheral artery disease, the national health and nutrition examination survey, 1999- 2004. Atherosclerosis 2010;213(2):586-91.
  11. Yarlioglues M, Kaya MG, Ardic I, Dogdu O, Kasapkara, HA, Gunturk E, et al. Relationship between mean platelet volume levels and subclinical target organ damage in newly diagnosed hypertensive patients. Blood Press 2011;20(2):92-7.
  12. Nadar SK, Blann AD, Kamath S, Beevers DG, Lip GY. Platelets indexes in relation to target organ damage in high-risk hypertensive patients. a substudy of the Anglo Scandinavian Cardiac Outcomes Trial (ASCOT). J Am Coll Cardiol 2004;21;44(2):415-22.
  13. Norgaz T, Hobikogl