Finally voltage-clamped simulations arecarried out to determine their dynamic behaviors based on squid giant axon.
📌 3 Maddede Bu Makale
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Amaç & Hipotez:In this paper, we investigate dynamics of voltage-gated ionic channels which are of great importance in integrating the information received by neurons.
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Temel Bulgular & Veri:Understanding of dynamical behavior of voltage-gated ionic channels plays a major role for determining underlying mechanism of spike activity and predicting the neuronal behavior.
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Sonuç & Katkı:Finally voltage-clamped simulations arecarried out to determine their dynamic behaviors based on squid giant axon.
🔬Tür:Modelleme & Sayısal Simülasyon
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri
Abstract
In this paper, we investigate dynamics of voltage-gated ionic channels which are of great importance in integrating the information received by neurons. Understanding of dynamical behavior of voltage-gated ionic channels plays a major role for determining underlying mechanism of spike activity and predicting the neuronal behavior. Investigation is carried out based on Hodgkin-Huxley (H-H) mathematical formalism. Ionic channel gate model is discussed briefly. Relaxation phenomenon is studied in the gate variables. Then effects of temperature on dynamics of gate variables are examined. Finally voltage-clamped simulations arecarried out to determine their dynamic behaviors based on squid giant axon.
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Bu Makaleye Atıf Yap
ÖZER, M., BAL, A. (2022). Function of voltage-gated ionic channels. Istanbul University Journal of Electrical and Electronics Engineering, Cilt: 4 - Sayı: 1, 1091–1104. https://ajindex.com/articles/543875
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