Dergiler / Haydarpaşa Numune Medical Journal / 2021 / Cilt: 61 - Sayı: 2

Prediction of In-Hospital Mortality in ST-Segment Elevation Myocardial Infarction: What is the Role of Thrombolysis in Myocardial Infarction Risk Index?

Sayfa
227–233
Yayın Tarihi
2022-10-19
DOI
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Discussion and Conclusion: Our study indicated that TIMI risk index calculated in the ED is an independent prognostic factor for in-hospital mortality in patients with STEMI.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Introduction: Thrombolysis in myocardial infarction (TIMI) risk index has been developed to predict the prognosis in pa- tients with coronary artery disease.
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Temel Bulgular & Veri:Methods: In this retrospective analysis, we evaluated the in-hospital mortality prognostic impact of TIMI risk index on 944 patients with STEMI treated with primary percutaneous coronary intervention.
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Sonuç & Katkı:Discussion and Conclusion: Our study indicated that TIMI risk index calculated in the ED is an independent prognostic factor for in-hospital mortality in patients with STEMI.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Introduction: Thrombolysis in myocardial infarction (TIMI) risk index has been developed to predict the prognosis in pa- tients with coronary artery disease. In this study, we evaluated the prognostic value of TIMI risk index in patients with ST-seg- ment elevation myocardial infarction (STEMI) when TIMI risk index was calculated in the emergency department (ED) and patients were referred to an interventional center. Methods: In this retrospective analysis, we evaluated the in-hospital mortality prognostic impact of TIMI risk index on 944 patients with STEMI treated with primary percutaneous coronary intervention. Patients were divided into two groups ac- cording to the presence of in-hospital mortality and the baseline features were compared between these groups. Multivar- iate analysis was implemented to detect independent predictors of in-hospital mortality. Results: TIMI risk index was an independent predictor (OR: 5.75; 95% confidence interval: 2.09–15.8; p=0.0007) of in-hospital mortality besides Killip stage, chronic kidney disease, and total ischemic time according to the results of the multivariate regression analysis. ROC analysis showed that the best cutoff value of the TIMI risk index to predict in-hospital mortality was 29.3 with 79.1% sensitivity and 80.7% specificity. Discussion and Conclusion: Our study indicated that TIMI risk index calculated in the ED is an independent prognostic factor for in-hospital mortality in patients with STEMI.

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Bu Makaleye Atıf Yap

AFACAN, M. A., TEKYOL, D., KOŞARGELİR, M., İNCEALTIN, O., KARABAY, C. Y., YAVUZ, B. G., TAYFUR, İ., TATAROĞLU, Ö. (2022). Prediction of In-Hospital Mortality in ST-Segment Elevation Myocardial Infarction: What is the Role of Thrombolysis in Myocardial Infarction Risk Index?. Haydarpaşa Numune Medical Journal, Cilt: 61 - Sayı: 2, 227–233. https://ajindex.com/articles/535932

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Kaynakça (11)

  1. Widimsky P, Wijns W, Fajadet J, de Belder M, Knot J, Aaberge L, et al. Reperfusion therapy for ST elevation acute myocardial infarction in Europe: Description of the current situation in 30 countries. Eur Heart J 2010;31:943–57
  2. Kristensen SD, Laut KG, Fajadet J, Kaifoszova Z, Kala P, Di Mario C, et al. Reperfusion therapy for ST elevation acute myocardial infarction 2010/2011: Current status in 37 ESC countries. Eur Heart J 2014;35:1957–70
  3. Gevaert SA, De Bacquer D, Evrard P, Convens C, Dubois P, Bo- land J, et al. Gender, TIMI risk score and in-hospital mortality in STEMI patients undergoing primary PCI: Results from the Belgian STEMI registry. Eurointervention 2014;9:1095–101
  4. Brown AJ, McCormick LM, Gajendragadkar PR, Hoole SP, West NE. Initial SYNTAX score predicts major adverse cardiac events after primary percutaneous coronary intervention. Angiology 2014;65:408–12
  5. Hayıroğlu Mİ, Keskin M, Uzun AO, Bozbeyoglu E, Yıldırımturk O, Kozan O, et al. Predictive value of SYNTAX score II for clinical outcomes in cardiogenic shock underwent primary percuta- neous coronary intervention; a pilot study. Int J Cardiovasc Imaging 2018;34:329–36
  6. Cerqueira AM Jr., Pereira LG, Souza TM, Correia VC, Alexandre FK, Gabriella SS, et al. Prognostic accuracy of the GRACE Score in octogenarians and nonagenarians with acute coronary syndromes. Arq Bras Cardiol 2018;110:24–9
  7. Wiviott SD, Morrow DA, Frederick PD, Robert P, Michael C, Carolyn HM, et al. Performance of the thrombolysis in myocar- dial infarction risk index in the national registry of myocardial infarction-3 and-4: A simple index that predicts mortality in ST-segment elevation myocardial infarction. J Am Coll Cardiol 2004;44:783–9
  8. Schiller NB, Shah PM, Crawford M, DeMaria A, Devereux R, Feigenbaum H, et al. Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. American society of echocardiography committee on stan- dards, subcommittee on quantitation of two-dimensional echocardiograms. J Am Soc Echocardiogr 1989;2:358–67
  9. Neumann FJ, Sousa-Uva M, Ahlsson A, Alfonso F, Banning AP, Benedetto U, et al. 2018 ESC/EACTS guidelines on myocardial revascularization. Eur Heart J 2019;40:87–165
  10. Thygesen K, Alpert JS, White HD, Jaffe AS, Katus HA, White HD, et al. Third universal definition of myocardial infarction. Eur Heart J 2012;33:2551–67
  11. Wang R, Mei B, Liao X, Lu X, Yan L, Lin M, et al. Determination of risk factors affecting the in-hospital p