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Dergiler / Haydarpaşa Numune Medical Journal / 2022 / Cilt: 62 - Sayı: 1

Is There a Relation Between Osteoporosis and ABO/Rh Blood Group Antigens?

Ali Erhan KAYALAR
Salim KATAR
Mustafa EFENDİOĞLU
Balkan ŞAHİN
Sayfa
70–74
Yayın Tarihi
2022-10-19
DOI
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Discussion and Conclusion: The findings of this study show that in addition to environmental and genetic factors, Rh blood antigen is also effective in the development of osteoporosis.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Introduction: ABO and Rhesus (Rh) blood group antigens play a role in the etiology of many diseases.
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Temel Bulgular & Veri:Methods: We retrospectively analyzed all patients, who underwent kyphoplasty for osteoporotic vertebral corpus fractures between May 2014 and October 2019 in Balikesir University Hospital.
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Sonuç & Katkı:Discussion and Conclusion: The findings of this study show that in addition to environmental and genetic factors, Rh blood antigen is also effective in the development of osteoporosis.
🔬Tür:Araştırma Makalesi
📍Kapsam:2014 Verileri
⚙️Değişkenler:Alan Parametreleri

Abstract

Introduction: ABO and Rhesus (Rh) blood group antigens play a role in the etiology of many diseases. The aim of this study is to determine their effects (the effects of these antigens) on the development of osteoporosis. Methods: We retrospectively analyzed all patients, who underwent kyphoplasty for osteoporotic vertebral corpus fractures between May 2014 and October 2019 in Balikesir University Hospital. Age, gender, fracture levels, T-scores, visual analog scale scores, oswestry disability index scores, and blood groups were taken from the hospital data system and recorded for each patient. The data of blood group distribution among the study patients were compared with the data of healthy individuals in the same region. Results: ABO blood groups results were not statistically significant in terms of the risk of developing osteoporotic vertebral fractures (OVFs). “Rh positive” blood type is associated with a high incidence of OVFs (91.5%) and the “Rh negative” blood group has the least association with OVFs (8.5%). Comparison of healthy controls with the OVF group revealed that Rh positive patients were at higher risk of OVF development. (p=0.026). Discussion and Conclusion: The findings of this study show that in addition to environmental and genetic factors, Rh blood antigen is also effective in the development of osteoporosis.

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Bu Makaleye Atıf Yap

KAYALAR, A. E., KATAR, S., EFENDİOĞLU, M., ŞAHİN, B. (2022). Is There a Relation Between Osteoporosis and ABO/Rh Blood Group Antigens?. Haydarpaşa Numune Medical Journal, Cilt: 62 - Sayı: 1, 70–74. https://ajindex.com/articles/535860

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Kaynakça (13)

  1. Ling X, Cummings SR, Mingwei Q, Xihe Z, Xioashu C, Nevitt M, et al. Vertebral fractures in Beijing, China: The Beijing Osteoporosis Project. J Bone Miner Res 2000;15:2019–25
  2. Wong CC, McGirt MJ. Vertebral compression fractures: A review of current management and multimodal therapy. J Multidiscip Healthc 2013;6:205–14
  3. Ensrud KE, Schousboe JT. Clinical practice. Vertebral fractures. N Engl J Med 2011;364:1634–42
  4. Fink HA, Milavetz DL, Palermo L, Nevitt MC, Cauley JA, Genant HK, et al. What proportion of incident radiographic vertebral deformities is clinically diagnosed and vice versa? J Bone Miner Res 2005;20:1216–22
  5. Zajickova K, Zofkova I. Osteoporosis: genetic analysis of multifactorial disease. Endocr Regul 2003;37:31–44
  6. Lee HJ, Kim SY, Kim GS, Hwang JY, Kim YJ, Jeong B, et al. Fracture, bone mineral density, and the effects of calcitonin receptor gene in postmenopausal Koreans. Osteoporos Int 2010;21:1351–60
  7. Delmas PD, Eastell R, Garnero P, Seibel MJ, Stepan J. The use of biochemical markers of bone turnover in osteoporosis. Committee of scientific advisors of the international osteoporosis foundation. Osteoporos Int 2000;11:S2–17
  8. Durmaz B., Biyokimyasal Göstergeler, Osteoporozda Kemik Kalitesi, Ed: Kutsal Y.G., 1. Baskı, Güneş Tıp Kitabevi. Ankara. 2004;s:175-192
  9. Tanakol R. Primer ve sekonder laboratuvar tetkikleri osteoporoz tanısında ve biyokimyasal kemik döngü göstergeleri. In: Domaniç Ü, Göksan S, editors. Osteoporoz. Ankara: Ortopedi ve Travmatoloji Yayın Evi; 2000. p.28–33
  10. Tural Ş, Kara N, Alaylı G. Genetics of Osteoporosis. Turk J Osteoporosis 2011;17:100–9
  11. Mornet E, Simon-Bouy B. Génétique de l'hypophosphatasie [Genetics of hypophosphatasia]. Arch Pediatr 2004;11:444–8. [Article in French] 12. Eyre D, Shao P, Weis MA, Steinmann B. The kyphoscoliotic type of Ehlers-Danlos syndrome (type VI): Differential effects on the hydroxylation of lysine in collagens I and II revealed by analysis of cross-linked telopeptides from urine. Mol Genet Metab 2002;76:211–6
  12. Heikkinen J, Toppinen T, Yeowell H, Krieg T, Steinmann B, Kivirikko KI, et al. Duplication of seven exons in the lysyl hydroxylase gene is associated with longer forms of a repetitive sequence within the gene and is a common cause for the type VI variant of Ehlers-Danlos syndrome. Am J Hum Genet 1997;60:48–56
  13. Giunta C, Randolph A, Steinmann B. Mutation analysis of the PLOD1 gene: An efficient multistep approach to the molecular diagnosis of th