In our article, we aimed to present a case who used linezolid for pneumonia and developed hyperlactatemia on the 12th day of treatment.
📌 3 Maddede Bu Makale
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Amaç & Hipotez:Lactate is a by-product of anaerobic respiration, and is cleared from blood by the liver and kidneys.
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Temel Bulgular & Veri:Lactate levels greater than 2 mmol/L is defined as hyperlactatemia, and higher than 4 mmol/l with acidosis is defined as lactic acidosis.
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Sonuç & Katkı:In our article, we aimed to present a case who used linezolid for pneumonia and developed hyperlactatemia on the 12th day of treatment.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri
Abstract
Lactate is a by-product of anaerobic respiration, and is cleared from blood by the liver and kidneys. Lactate levels greater than 2 mmol/L is defined as hyperlactatemia, and higher than 4 mmol/l with acidosis is defined as lactic acidosis. It is the most common cause of metabolic acidosis in hospitalized patients. Linezolid is an antibiotic in the oxazolidinone class that directly inhibits protein synthesis in the mitochondria of bacteria and may cause lactic acidosis, which may have a high mortality. In our article, we aimed to present a case who used linezolid for pneumonia and developed hyperlactatemia on the 12th day of treatment.
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Bu Makaleye Atıf Yap
KAYATAŞ, K., DOĞAN, M. K., YIĞCI, Ş. B., YEŞİLYURT, D. (2022). Hyperlactatemia Due to Linezolid Use: A Case Report. Haydarpaşa Numune Medical Journal, Cilt: 62 - Sayı: 2, 232–234. https://ajindex.com/articles/535833
Sargın G, Yavaşoğlu İ, Kadıköylü G, Bolaman Z. Laktik asidoz: Olgular üzerinden kısa bir gözden geçirme. Yoğun Bakım Derg 2011;3:63–6. 3 Im JH, Baek JH, Kwon HY, Lee JS. Incidence and risk factors of linezolid-induced lactic acidosis. Int J Infect Dis 2015;31:47– 52
Mao Y, Dai D, Jin H, Wang Y. The risk factors of linezolid-induced lactic acidosis: A case report and review. Medicine (Baltimore) 2018;97:e12114