Dergiler / Haseki Tıp Bülteni / 2021 / Cilt: 59 - Sayı: 5

The Association Between Erectile Dysfunction and Subclinical Hypothyroidism in Males with Type 2 Diabetes Mellitus

Sayfa
411–418
Yayın Tarihi
2022-10-17
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

The TSH levels were significantly different between the ED groups (p

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Aim: Overt hypothyroidism is known to affect sexual functions, but data on subclinical hypothyroidism (SCH) are insufficient.
📊
Temel Bulgular & Veri:We aimed to investigate the relationship between erectile dysfunction (ED) and SCH in men with type 2 Diabetes Mellitus.
💡
Sonuç & Katkı:The TSH levels were significantly different between the ED groups (p
🔬Tür:Uygulamalı Anket & Alan Araştırması
📍Kapsam:2018 Verileri
⚙️Değişkenler:Alan Parametreleri

Abstract

Aim: Overt hypothyroidism is known to affect sexual functions, but data on subclinical hypothyroidism (SCH) are insufficient. We aimed to investigate the relationship between erectile dysfunction (ED) and SCH in men with type 2 Diabetes Mellitus. Methods: This cross-sectional study included 117 diabetic patients aged between 45-70 years who applied to our outpatient clinic between March and June 2018. Biochemical blood tests and levels of hormones were analyzed. International erectile function index-5 (IIEF-5) questionnaire was applied for the assessment of ED. According to the IIEF-5 questionnaire scores, patients were grouped as severe ED (n=47), moderate ED (n=46), and no ED (n=24). Patients were also grouped according to the level of thyroid-stimulating hormone (TSH) into 3 groups; 0.27-2.49 mU/l (n=58), 2.5-4.2 mU/l (n=33), and >4.2 mU/l (n=26). Statistically significance level was set at 0.05. Results: 40% of the patients had severe ED and 39% moderate ED, while 21% had no ED. The TSH levels were significantly different between the ED groups (p

🔖

Bu Makaleye Atıf Yap

BASAT, O., BAYGÜL, A., BASAT, S. U., SİVRİTEPE, R. (2022). The Association Between Erectile Dysfunction and Subclinical Hypothyroidism in Males with Type 2 Diabetes Mellitus. Haseki Tıp Bülteni, Cilt: 59 - Sayı: 5, 411–418. https://ajindex.com/articles/534997

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (15)

  1. DeFronzo RA, Ferrannini E, Groop L, et al. Type 2 diabetes mellitus. Nat Rev Dis Primers 2015;1:15019
  2. Veelen A, Erazo-Tapia E, Oscarsson J, Schrauwen P. Type 2 diabetes subgroups and potential medication strategies in relation to effects on insulin resistance and beta-cell function: A step toward personalised diabetes treatment? Mol Metab 2020;101158
  3. Salonia A, Bettocchi C, Boeri L, et al. European Association of Urology Guidelines on Sexual and Reproductive Health-2021 Update: Male Sexual Dysfunction. Eur Urol 2021;80:333-57
  4. Kouidrat Y, Pizzol D, Cosco T, et al. High prevalence of erectile dysfunction in diabetes: a systematic review and metaanalysis of 145 studies. Diabet Med 2017;34:1185-92
  5. Wang XY, Huang W, Zhang Y. Relation between hypertension and erectile dysfunction: a meta-analysisof cross-section studies. Int J Impot Res 2018;30:141-6
  6. Leisegang K, Sengupta P, Agarwal A, Henkel R. Obesity and male infertility: Mechanisms and management. Andrologia 2021;53:e13617
  7. Lotti F, Maseroli E, Fralassi N, et al. Is thyroid hormones evaluation of clinical value in the work-up of males of infertile couples? Hum Reprod 2016;31:518-29
  8. Patel N, Kashanian JA. Thyroid Dysfunction and Male Reproductive Physiology. Semin Reprod Med 2016;34:356- 60
  9. Yoo WS, Chung HK. Subclinical Hypothyroidism: Prevalence, Health Impact, and Treatment Landscape. Endocrinol Metab (Seoul) 2021;36:500-13. 10. Štěpánek L, Horáková D, Štěpánek L, et al. Free triiodothyronine/free thyroxine (FT3/FT4) ratio is strongly associated with insulin resistance in euthyroid and hypothyroid adults: a cross-sectional study. Endokrynol Pol 2021;72:8-13
  10. American Diabetes Association
  11. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes-2021. Diabetes Care 2021;44(Suppl 1):15-33
  12. Rosen RC, Cappelleri JC, Smith MD, Lipsky J, Peña BM. Development and evaluation of an abridged, 5-item version of the International Index of Erectile Function (IIEF-5) as a diagnostic tool for erectile dysfunction. Int J Impot Res 1999;11:319-26
  13. Turunc T, Deveci S, Güvel S, Peşkircioğlu L. The assessment of Turkish validation with 5 question version of International Index of Erectile Function (IIEF-5). Turk J Urol 2007;33:45-9
  14. Peeters RP. Subclinical Hypothyroidism. N Engl J Med 2017;376:2556-65
  15. Cripps SM, Mattiske DM, Pask AJ. Erectile Dysfunction in Men on the Rise: Is There a Link with Endocrine Disrupting Chemicals? Sex Dev 2021;16:1-26.