KaydedilenlerDerginizi ekleyin

Dergiler / Hacettepe Journal of Biology and Chemistry / 2005 / Cilt: 34 - Sayı:

Placental structure in the rats: Histological and immunohistochemical studies

Evrim Arzu KOÇKAYA
Mehmet Turan AKAY
Sayfa
19–35
Yayın Tarihi
2022-10-17
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Time- and region dependent changes in the immunolocalization of TN, type IV collagen, EGF and EGFR were determined in the placentas of rats during their gestational period.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:The aim of this paper is to review the current knowledge of the localization and function of TN (Tenascin) and type IV collagen and EGF (Epidermal Growth Factor) and EGFR (Epidermal Growth Factor Receptor) in normal rat placenta formation.
📊
Temel Bulgular & Veri:Therefore, the samples of placenta obtained from rats on days 10, 12, 14, 16, 18, 20 and 21 of gestation were evaluated morphologically; fixed and stained with H&E for histology method for immunohistochemistry.
💡
Sonuç & Katkı:Time- and region dependent changes in the immunolocalization of TN, type IV collagen, EGF and EGFR were determined in the placentas of rats during their gestational period.
🔬Tür:Literatür & Derleme Çalışması
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

The aim of this paper is to review the current knowledge of the localization and function of TN (Tenascin) and type IV collagen and EGF (Epidermal Growth Factor) and EGFR (Epidermal Growth Factor Receptor) in normal rat placenta formation. In this study, immunolocalization of ECM (Extracellular matrix) components such as TN and type IV collagen and EGF and its receptor in the placenta of Wistar albino rats were determined. Therefore, the samples of placenta obtained from rats on days 10, 12, 14, 16, 18, 20 and 21 of gestation were evaluated morphologically; fixed and stained with H&E for histology method for immunohistochemistry. Besides, during the experiment, body weights of all rats were recorded.Morphological and histological investigation showed that there were changes in placental histology with placental development. Time- and region dependent changes in the immunolocalization of TN, type IV collagen, EGF and EGFR were determined in the placentas of rats during their gestational period.

🔖

Bu Makaleye Atıf Yap

KOÇKAYA, E. A., AKAY, M. T. (2022). Placental structure in the rats: Histological and immunohistochemical studies. Hacettepe Journal of Biology and Chemistry, Cilt: 34 - Sayı:, 19–35. https://ajindex.com/articles/529399

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (1)

  1. Badylak, S.F., The extracellular matrix as a scaffold for tissue reconstruction. Seminars in Cell and Developmental Biology, 13, 377-83, 2002. 2.Laurie, G.W., Leblond, C.P. and Martin, G.R., Light microscopic immunolocalization of type IV collagen, laminin, heparan sulfate proteoglycan and fibronectin in the basement membranes of a variety of rats organs. The American Journal of Anatomy, 167, 71-82,1983. 3.Chiquet-Ehrismann, R., Mackie, E.J., Pearson, C.A., Sakakura, T., Tenascin: an extracellular matrix protein involved in tissue interactions during fetal development and oncogenesis. Cell, 47, 131-39, 1986. 4.Carpenter, G. and Cohen, S., Epidermal growth factor. Ann Rev of Biochem, 48, 193-216, 1979. 5.Gospodarowicz, D., Greenburg, H., Bialecki, L. and Zetter, R.B., Factors involved in the modulation of cell proliferation in vitro and in vivo: The role of fibroblast and epidermal growth factors in the proliferative response of mammalian cells. In vitro, 14, 85-9, 1975. 6.Maruo, T., Matsuo, H., Oishi, T., Hayashi, M., Nishino, R. and Mochizuki, M., Induction of differentiatiated trophoblast function by epidermal growth factor: Relation of immunohistochemically detected cellular epidermal growth factor receptor levels. J Clinical Endocrinology and Metabolism, 64(4), 744-50,1987. 7.Fisher, D.A. and Lakshmanan, J., Metabolism and effects of epidermal growth factor and related growth factors in mammals. Endocrine Reviews, 11(3), 418-42, 1990. 8.Hamilton, M.N., Growth factors and development. Curr Topics in Dev Biol, 24, 1-347, 1990. 9.Lala, P.K. and Graham, C.H., Mechanism of trophoblast invasiveness and their control: the role of proteases and protease inhibitors. Cancer Metas Reviews, 9, 369-79, 1990. 10.Lala, P.K. and Hamilton, G.S., Growth factors, proteases and protease inhibitors in the maternal-fetal dialogue. Placenta, 17, 545-55, 1996. 11.Eguchi, Y., Yamamoto, M., Arishima, K., Shirai, M., Wakabayashi, K., Leichter, J. and Lee, M., Histological changes in the placenta induced by maternal alcohol consumption in the rat. Biol Neonate, 56,158-64, 1989. 12.Abel, E.L., A surprising effect of paternal alcohol treatment of rat fetuses. Alcohol, 12(1), 1-6, 1995. 13.Forsberg, H., Wentzel, P. and Eriksson, J., Maternal diabetes alters extracellular matrix protein levels in rat placentas. Am J Obstet Gynecol, 179, 772-78, 1998. 14.Bridgman, J. A morphological study of the development of the placenta of the rat. J Morphol, 83,61-80, 1948. 15.Davies, J. and Gla