Difficulties in synthesis and characterization of viral capsid peptides

Temel Bulgular & Veri:In this work we synthesised 3 different viral peptide sequences with microwave enhanced Solid Phase Peptide Synthesis (SPPS) method and characerized with LC-ESI-MS system.

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Sonuç & Katkı:We briefly describe the difficulties in synthesis and characterization.

🔬Tür:Araştırma Makalesi

📍Kapsam:Genişletilmiş Akademik Örneklem

⚙️Değişkenler:Alan Parametreleri

Abstract

Peptides and proteins play a central role in numerous biological and physiological processes in living organisms. Viral capsid pepdides are part of the viruses outer shell of genetic materials. Viruses are recognized by immune system via capsid peptides. Depending on this property of capsid peptides, totally synthetic vaccine prototypes can be developed. In this work we synthesised 3 different viral peptide sequences with microwave enhanced Solid Phase Peptide Synthesis (SPPS) method and characerized with LC-ESI-MS system. We briefly describe the difficulties in synthesis and characterization.

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Bu Makaleye Atıf Yap

TOPUZOĞULLARI, M., KARABULUT, E., MUSTAFAEVA, Z., ÖZDEMİR, Z. Ö. (2022). Difficulties in synthesis and characterization of viral capsid peptides. Hacettepe Journal of Biology and Chemistry, Cilt: 36 - Sayı: 4, 329–337. https://ajindex.com/articles/529334

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Kaynakça (14)

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