This report describes the successful treatment of an immunsupressed host suffering from severe aspergillus osteomyelitis and tuberculosis co-infection, using liposomal amphotericin B.
📌 3 Maddede Bu Makale
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Amaç & Hipotez:Fungal organisms are increasingly recognized as serious and potentially fatal pathogens in the immunosuppressed host.
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Temel Bulgular & Veri:There is a critical need for alternatives to amphotericin B as a treatment for such life-threatening fungal infections as invasive aspergillosis; because although amphotericin B is used to treat fungal infections that are resistant to other antifungal drugs, such as fluconazole and ketoconazole, there are severe toxic effects of amphotericin B include fever, chills, muscle pain, phlebitis, vomiting, potassium loss, kidney dysfunctions and anemia.
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Sonuç & Katkı:This report describes the successful treatment of an immunsupressed host suffering from severe aspergillus osteomyelitis and tuberculosis co-infection, using liposomal amphotericin B.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri
Abstract
Fungal organisms are increasingly recognized as serious and potentially fatal pathogens in the immunosuppressed host. There is a critical need for alternatives to amphotericin B as a treatment for such life-threatening fungal infections as invasive aspergillosis; because although amphotericin B is used to treat fungal infections that are resistant to other antifungal drugs, such as fluconazole and ketoconazole, there are severe toxic effects of amphotericin B include fever, chills, muscle pain, phlebitis, vomiting, potassium loss, kidney dysfunctions and anemia. Liposomal bounded amphotericin B also shows a distinctly lower toxic profile, even in higher concentrations in the plasma, than conventional amphotericin B. This report describes the successful treatment of an immunsupressed host suffering from severe aspergillus osteomyelitis and tuberculosis co-infection, using liposomal amphotericin B.
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Bu Makaleye Atıf Yap
ERGÜVEN, M., ÖZÜMÜZTOPRAK, N., SAÇAR, O. (2022). Aspergillus osteomiyelitinde lipozomal amfoterisin B kullanımı. Göztepe Tıp Dergisi, Cilt: 18 - Sayı: 3, 191–192. https://ajindex.com/articles/526485
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