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AI InsightRESULTS: Frequencies determined at the end of the third month were significantly increased (p
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Özet
! OBJECTIVE: In this study, we tried to investigate acute mutagenic effects of monophasic oral j contraceptives in standard doses on sister chromatid exchange and Mitotic index. i STUDY DESING: 35 women using oral contraceptives for three months were included into the study. I They were given 0,03 mg of ethinyl estradiol and 0,3 mg of norgestrel continuously for three weeks i and 75 mg ferrous for the fourth week. Sister chromatid exchange and mitotic index frequencies were recorded from peripheral blood leucocytes in a blinded fashion. RESULTS: Frequencies determined at the end of the third month were significantly increased (p
Abstract
! OBJECTIVE: In this study, we tried to investigate acute mutagenic effects of monophasic oral j contraceptives in standard doses on sister chromatid exchange and Mitotic index. i STUDY DESING: 35 women using oral contraceptives for three months were included into the study. I They were given 0,03 mg of ethinyl estradiol and 0,3 mg of norgestrel continuously for three weeks i and 75 mg ferrous for the fourth week. Sister chromatid exchange and mitotic index frequencies were recorded from peripheral blood leucocytes in a blinded fashion. RESULTS: Frequencies determined at the end of the third month were significantly increased (p