Dergiler / GORM:Gynecology Obstetrics & Reproductive Medicine / 2021 / Cilt: 27 - Sayı: 2

Are the Mean Platelet Volume and Neutrophil/Lymphocyte Ratio Predictive for Gestational Cholestasis?

Sayfa
105–108
Yayın Tarihi
2022-10-17
DOI
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There was a statistically significant difference between the two groups for mean platelet volume (p

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Amaç & Hipotez:OBJECTIVES: We aimed to determine whether mean platelet volume value and/or neutrophil/lymphocyte ratio values are useful as a predictive marker for gestational cholestasis.
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Temel Bulgular & Veri:STUDY DESIGN: Retrospective analysis of the data of patients diagnosed with pregnancy cholestasis between 2018-2019 in a perinatology clinic. 352 pregnant women were enrolled in the study (122 pregnant women with Intrahepatic cholestasis as study group and 230 pregnant women with no morbidity as the control group) RESULTS: Mean platelet volume was significantly higher in pregnant women with intrahepatic cholestasis compared to the healthy controls, 9.30 (7-18) and 8.6 (6.7-11.5), respectively.
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Sonuç & Katkı:There was a statistically significant difference between the two groups for mean platelet volume (p
🔬Tür:Araştırma Makalesi
📍Kapsam:2018-2019 Verileri
⚙️Değişkenler:Alan Parametreleri

Abstract

OBJECTIVES: We aimed to determine whether mean platelet volume value and/or neutrophil/lymphocyte ratio values are useful as a predictive marker for gestational cholestasis. STUDY DESIGN: Retrospective analysis of the data of patients diagnosed with pregnancy cholestasis between 2018-2019 in a perinatology clinic. 352 pregnant women were enrolled in the study (122 pregnant women with Intrahepatic cholestasis as study group and 230 pregnant women with no morbidity as the control group) RESULTS: Mean platelet volume was significantly higher in pregnant women with intrahepatic cholestasis compared to the healthy controls, 9.30 (7-18) and 8.6 (6.7-11.5), respectively. The neutrophil/lymphocyte ratio was significantly higher in pregnant women with intrahepatic cholestasis compared to the healthy controls, 3.93 (0.46-13.75) and 4.25 (0.87-17.1), respectively. There was a statistically significant difference between the two groups for mean platelet volume (p

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Bu Makaleye Atıf Yap

ÖRGÜL, G., ŞAHİN, D., YÜCEL, A., TOLUNAY, H. E., EROĞLU, H., SARSMAZ, K. (2022). Are the Mean Platelet Volume and Neutrophil/Lymphocyte Ratio Predictive for Gestational Cholestasis?. GORM:Gynecology Obstetrics & Reproductive Medicine, Cilt: 27 - Sayı: 2, 105–108. https://ajindex.com/articles/525832

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Kaynakça (12)

  1. Ovadia C, Williamson C. Intrahepatic cholestasis of pregnancy: Recent advances. Clin Dermatol. 2016;34(3):327- 34. doi: 10.1016/j.clindermatol.2016.02.004
  2. Oh CC, Oon H. Intrahepatic cholestasis of pregnancy. Cutis. 2018;102(3): E26-E27. PMID: 30372720
  3. Ozkan S, Ceylan Y, Ozkan OV, Yildirim S. Review of a challenging clinical issue: Intrahepatic cholestasis of pregnancy. World J Gastroenterol. 2015;21(23):7134-41. doi: 10.3748/wjg.v21.i23.7134
  4. Turkmen Gencosmanoglu G, Yilmaz ZV, Oguz Y, Yakut K, Sanhal CY, Uygur D. Intrahepatic cholestasis of pregnancy is associated with gestational diabetes mellitus. Gynecol Obstet Reprod Med. 2019;25(3):133-7 doi: 10. 21613/GORM.2018.855
  5. Hershko Klement A, Hadi E, Asali A, Shavit T, Wiser A, Haikin E, et al. Neutrophils to lymphocytes ratio and platelets to lymphocytes ratio in pregnancy: A population study. PLoS One. 2018;13(5):e0196706. doi: 10.1371/ journal.pone.0196706. eCollection 2018
  6. İlhan M, İlhan G, Gök AFK, Bademler S, Verit Atmaca F, Ertekin C. Evaluation of neutrophil-lymphocyte ratio, platelet-lymphocyte ratio and red blood cell distribution width-platelet ratio as early predictor of acute pancreatitis in pregnancy. J Matern Fetal Neonatal Med. 2016; 29(9):1476-80. doi: 10.3109/14767058.2015.1051026
  7. Yıldız Ç, Karakuş S, Akkar Bozoklu Ö, Topbaş T, Çetin M, Yanık A, et al. The significance of neutrophil-lymphocyte ratio and mean corpuscular volume in diagnosis of preeclampsia. Gynecol Obstet Reprod Med. 2016; 22(2):75-9
  8. Biberoglu E, Kirbas A, Daglar K, Kara O, Karabulut E, Yakut HI, et al. Role of inflammation in intrahepatic cholestasis of pregnancy. J Obstet Gynaecol Res. 2016; 42(3):252-7. doi: 10.1111/jog.12902. Epub 2016 Jan 19
  9. Kauppila A, Korpela H, Mäkilä UM, Yrjänheikki E. Low serum selenium concentration and glutathione peroxidase activity in intrahepatic cholestasis of pregnancy. Br Med J (Clin Res Ed). 1987;294(6565):150-2. doi: 10.1136/ bmj. 294.6565.150
  10. Alsulyman OM, Ouzounian JG, Ames-Castro M, Goodwin TM. Intrahepatic cholestasis of pregnancy: perinatal outcome associated with expectant management. Am J Obstet Gynecol. 1996;175(4 Pt 1):957-60. doi: 10. 1016/s0002-9378(96)80031-7
  11. Germain AM, Kato S, Carvajal JA, Valenzuela GJ, Valdes GL, Glasinovic JC. Bile acids increase response and expression of human myometrial oxytocin receptor. Am J Obstet Gynecol. 2003;189(2):577-82. Doi: 10.1016/s000 2-9378(96)80031-7
  12. Sheikh Abdul Kadir SH, Miragoli M, Abu-H