KaydedilenlerDerginizi ekleyin

Dergiler / Glokom Katarakt / 2021 / Cilt: 16 - Sayı: 4

Evaluation of Tear Film Layer and Meibomian Gland Morphology in Glaucoma Patients

Cafer Tanrıverdi
Burcu Nurözler Tabakcı
Sayfa
188–193
Yayın Tarihi
2022-10-18
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

The changes in the MG occurring in glaucoma patients may be associated with long-term use of topical antiglaucoma medication.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Purpose: This study aims to investigate the changes in meibomian gland (MG) morphology and tear film layer in glaucoma patients.
📊
Temel Bulgular & Veri:Materials and Methods: The study included 88 eyes of 44 glaucoma patients and 166 eyes of 83 healthy subjects.
💡
Sonuç & Katkı:The changes in the MG occurring in glaucoma patients may be associated with long-term use of topical antiglaucoma medication.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Purpose: This study aims to investigate the changes in meibomian gland (MG) morphology and tear film layer in glaucoma patients. Materials and Methods: The study included 88 eyes of 44 glaucoma patients and 166 eyes of 83 healthy subjects. Noncontact meibography and noninvasive tear break-up time (TBUT) tests were performed with the Sirius Scheimpflug camera. Results: The total meiboscore, first and mean noninvasive TBUT, invasive TBUT, and OSDI scores were 3.57 ± 1.57, 9.24 ± 5.86, 10.76 ± 4.81, 7.62 ± 3.04, and 14.11 ± 10.48, respectively, for the glaucoma group and 2.43 ± 1.42, 11.17 ± 5.72, 12.30 ± 4.65, 9.56 ± 3.39, and 8.17 ± 7.17, respectively, for the control group. Conclusion: Morphological changes in the MG, decreases in TBUT tests and increases in OSDI scores were observed in glaucoma patients. The changes in the MG occurring in glaucoma patients may be associated with long-term use of topical antiglaucoma medication.

🔖

Bu Makaleye Atıf Yap

Tanrıverdi, C., Tabakcı, B. N. (2022). Evaluation of Tear Film Layer and Meibomian Gland Morphology in Glaucoma Patients. Glokom Katarakt, Cilt: 16 - Sayı: 4, 188–193. https://ajindex.com/articles/525759

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (15)

  1. Quigley HA, Broman AT. The number of people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol. 2006;90:262-7
  2. Tham YC, Li X, Wong TY, et al. Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis. Ophthalmology. 2014; 121: 2081-90
  3. Schehlein EM, Novack G, Robin AL. New pharmacotherapy for the treatment of glaucoma. Expert Opin Pharmacother. 2017; 18: 1939-46
  4. Sihota R, Angmo D, Ramaswamy D, et al. Simplifying "target" intraocular pressure for different stages of primary open-angle glaucoma and primary angle-closure glaucoma. Indian J Ophthalmol. 2018; 66: 495-505
  5. Leung EW, Medeiros FA, Weinreb RN. Prevalence of ocular surface disease in glaucoma patients. J Glaucoma. 2008; 17: 350-5
  6. Fechtner RD, Godfrey DG, Budenz D, et al. Prevalence of ocular surface complaints in patients with glaucoma using topical intraocular pressure-lowering medications. Cornea. 2010; 29: 618-21
  7. Chawla A, McGalliard JN, Batterbury M. Use of eyedrops in glaucoma: how can we help to reduce non-compliance? Acta Ophthalmol Scand. 2007; 85: 464
  8. Miljanović B, Dana R, Sullivan DA, et al. Impact of dry eye syndrome on vision-related quality of life. Am J Ophthalmol. 2007; 143: 409-15
  9. Shimazaki J, Hanada K, Yagi Y, et al. Changes in ocular surface caused by antiglaucomatous eyedrops: prospective, randomised study for the comparison of 0.5% timolol v 0. 12% unoprostone. Br J Ophthalmol. 2000; 84: 1250-4
  10. Burstein NL. The effects of topical drugs and preservatives on the tears and corneal epithelium in dry eye. Trans Ophthalmol Soc. 1985;104:402-9
  11. Wilson WS, Duncan AJ, Jay JL. Effect of benzalkonium chloride on the stability of the precorneal tear film in rabbit and man. Br J Ophthalmol. 1975;59:667-9
  12. Burstein NL. Preservative cytotoxic threshold for benzalkonium chloride and chlorhexidine digluconate in cat and rabbit corneas. Invest Ophthalmol Vis Sci. 1980; 19:308- 13
  13. Pauly A, Meloni M, Brignole-Baudouin F, et al. Multiple endpoint analysis of the 3D-reconstituted corneal epithelium after treatment with benzalkonium chloride: early detection of toxic damage. Invest Ophthalmol Vis Sci. 2009; 50:1644- 52
  14. Nelson JD, Shimazaki J, Benitez-del-Castillo JM, et al. The international workshop on meibomian gland dysfunction: report of the de finition and classi fication subcommittee. Invest Ophthalmol Vis Sci. 2011;52:1930-7
  15. Schaumberg DA, Nichols JJ, Papas EB, et al. The