KaydedilenlerDerginizi ekleyin

Dergiler / Gazi Medical Journal / 2014 / Cilt: 25 - Sayı: 1

Obez kadınlarda paraoksonaz1 aktivitesinin lipit metabolizması ile ilişkisi

The relationship of paraoxonase 1 activity with lipid metabolism in obese women

Mehmet TOSUN
Fatih ÖZCAN
Erdinç SERİN
Güler BUĞDAYCI
Sayfa
11–15
Yayın Tarihi
2022-10-19
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Group 1 had 30 abdominal obese patients, group 2 had 30 gynoid obeses and group 3 included 30 healthy control subjects.Results: There was a statistically significant difference between the triglyceride, high-density lipoprotein cholesterol (HDL-C), apo B, direct low-density lipoprotein cholesterol (D-LDL-C), high sensitive-CRP (hsCRP), homeostasis model insulin resistance (HOMA-IR) levels of group 1 and 2 (p=0.001, p

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Objective: The aim of this study was to identify the effects of serum lipids, apolipoprotein (apo) A-I, apo B and paraoxonase/arylesterase (PON1) activity on obesity in women.Methods: The study was conducted on 90 subjects categorized into three groups; there were 30 women in each group with an age range of 18-48 years.
📊
Temel Bulgular & Veri:Objective: The aim of this study was to identify the effects of serum lipids, apolipoprotein (apo) A-I, apo B and paraoxonase/arylesterase (PON1) activity on obesity in women.Methods: The study was conducted on 90 subjects categorized into three groups; there were 30 women in each group with an age range of 18-48 years.
💡
Sonuç & Katkı:Group 1 had 30 abdominal obese patients, group 2 had 30 gynoid obeses and group 3 included 30 healthy control subjects.Results: There was a statistically significant difference between the triglyceride, high-density lipoprotein cholesterol (HDL-C), apo B, direct low-density lipoprotein cholesterol (D-LDL-C), high sensitive-CRP (hsCRP), homeostasis model insulin resistance (HOMA-IR) levels of group 1 and 2 (p=0.001, p
🔬Tür:Modelleme & Sayısal Simülasyon
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Objective: The aim of this study was to identify the effects of serum lipids, apolipoprotein (apo) A-I, apo B and paraoxonase/arylesterase (PON1) activity on obesity in women.Methods: The study was conducted on 90 subjects categorized into three groups; there were 30 women in each group with an age range of 18-48 years. Group 1 had 30 abdominal obese patients, group 2 had 30 gynoid obeses and group 3 included 30 healthy control subjects.Results: There was a statistically significant difference between the triglyceride, high-density lipoprotein cholesterol (HDL-C), apo B, direct low-density lipoprotein cholesterol (D-LDL-C), high sensitive-CRP (hsCRP), homeostasis model insulin resistance (HOMA-IR) levels of group 1 and 2 (p=0.001, p

Abstract

Objective: The aim of this study was to identify the effects of serum lipids, apolipoprotein (apo) A-I, apo B and paraoxonase/arylesterase (PON1) activity on obesity in women.Methods: The study was conducted on 90 subjects categorized into three groups; there were 30 women in each group with an age range of 18-48 years. Group 1 had 30 abdominal obese patients, group 2 had 30 gynoid obeses and group 3 included 30 healthy control subjects.Results: There was a statistically significant difference between the triglyceride, high-density lipoprotein cholesterol (HDL-C), apo B, direct low-density lipoprotein cholesterol (D-LDL-C), high sensitive-CRP (hsCRP), homeostasis model insulin resistance (HOMA-IR) levels of group 1 and 2 (p=0.001, p

🔖

Bu Makaleye Atıf Yap

TOSUN, M., ÖZCAN, F., SERİN, E., BUĞDAYCI, G. (2022). Obez kadınlarda paraoksonaz1 aktivitesinin lipit metabolizması ile ilişkisi. Gazi Medical Journal, Cilt: 25 - Sayı: 1, 11–15. https://ajindex.com/articles/519871

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (12)

  1. Ogden CL, Yanovski SZ, Carroll MD, Flegal KM. The epidemiology of obesity. Gastroenterology 2007; 132: 2087-102.
  2. Kota SK, Meher LK, Kota SK, Jammula S, Krishna SVS. Implications of serum paraoxonase activity in obesity, diabetes mellitus, and dyslipidemia. Indian J Endocrinol and Metab 2013; 17: 402-12.
  3. Faraj M, Lavoie ME, Messier L, Bastard JP, Prud’homme D. Reduction in serum apoB is associated with reduced inflammation and insulin resistance in post-menopausal women: A MONET study. Atherosclerosis 2010; 211: 682-8.
  4. Tabur S, Torun AN, Sabuncu T, Turan MN, Celik H, Ocak AR et al. Non-diabetic metabolic syndrome and obesity do not affect serum paraoxonase and arylesterase activities but do affect oxidative stress and inflammation. Eur Journal Endocrinol2010; 162: 535-41.
  5. Furlong CE, Suzuki SM, Stevens RC. Human PON1, a biomarker of risk of disease and exposure. Chem Biol Interact 2010; 187: 355-61.
  6. Dragonov DI, La Du NB. Pharmacogenetics of paraoxonases: a brief review. Naunyn-Schmiedeberg’s. Arch Pharmocol 2004; 369: 78-88.
  7. Camps J, Marsillach J, Joven J. The paraoxonases: role in human diseases and methodological diffuculties in measurement. Crit Rev Clin Lab Sci 2009; 46:83-106.
  8. Chudek J, Wiecek A. Adipose tissue, inflammation and endothelial dysfunction. Pharmacol Rep 2006; 58: 81-8.
  9. National Institutes of Health, National Heart, Lung, and Blood Institute: Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults-in evidence report. Obes Res 1998; 6: 51-209.
  10. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher BF, Turner RC. Homeostasis model assesment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabeteologia 1985; 28: 412-9.
  11. Salgado JV, Neves FA, Bastos MG, Franca AK, Brito DJ, Santas EM. Monitoring renal function: measured and estimated glomerular filtration rates - a review. Braz J Med Biol Res 2010; 43: 528-36. Monteiro R and Azevedo I. Chronic inflammation in obesity and the metabolic syndrome. Mediators of Inflammation 2010; doi: 10.1155/2010 289645. Seres I, Bajnok L, Harangi M, Sztanek F, Koncsos P, Paragh G. Alteration of PON1 activity in adult and childhood obesity and its relation to adipokine levels. Adv Exp Med Biol 2010; 660: 129-42.
  12. Tabak O, Gelişgen R, Çicekci H, Şenateş E, Erdenen F, Müderrisoğlu C et al. Circulating levels of adiponectin, orexin-A, ghrelin and the antioxidant paraoxonase-1 in metabolic sydrome. Minerva Med 201