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Dergiler / Eurasian Journal of Medical Investigation / 2019 / Cilt: 3 - Sayı: 4

Investigation of the Effect of Pre-Transplantation Iron Overload on Posttransplantation Complications and Survival in Patients with Hematopoietic Stem Cell Transplantation

Aydın AYTEKİN
Sayfa
269–274
Yayın Tarihi
2022-10-12
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

The study cohort was dividedinto 2 groups as low ferritin group (ferritin

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Objectives: Many studies have shown that ferritin values that are used as an indicator of iron overload are associatedwith adverse outcomes after bone marrov transplantation.
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Temel Bulgular & Veri:The aim of this study was to evaluate the effect of ferritin ondevelopment of complications after transplantation.Methods: The data of the patients who underwent HSCT (Hematopoietic Stem Cell Transplantation) in HacettepeUniversity Faculty of Medicine, June 2001 - March 2012 were retrospectively reviewed.
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Sonuç & Katkı:The study cohort was dividedinto 2 groups as low ferritin group (ferritin
🔬Tür:Literatür & Derleme Çalışması
📍Kapsam:2001 Verileri
⚙️Değişkenler:Alan Parametreleri

Abstract

Objectives: Many studies have shown that ferritin values that are used as an indicator of iron overload are associatedwith adverse outcomes after bone marrov transplantation. The aim of this study was to evaluate the effect of ferritin ondevelopment of complications after transplantation.Methods: The data of the patients who underwent HSCT (Hematopoietic Stem Cell Transplantation) in HacettepeUniversity Faculty of Medicine, June 2001 - March 2012 were retrospectively reviewed. The study cohort was dividedinto 2 groups as low ferritin group (ferritin

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Bu Makaleye Atıf Yap

AYTEKİN, A. (2022). Investigation of the Effect of Pre-Transplantation Iron Overload on Posttransplantation Complications and Survival in Patients with Hematopoietic Stem Cell Transplantation. Eurasian Journal of Medical Investigation, Cilt: 3 - Sayı: 4, 269–274. https://ajindex.com/articles/508719

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Kaynakça (5)

  1. Göker H, Aksu S, Haznedaroğlu İC, Büyükaşık Y, Sayınalp N, Turgut M, et al. Erişkinlerde hematopoietik kök hücre transplantasyonu: Hacettepe hematoloji deneyimi 2001-2005
  2. Alessandrino EP, Della Porta MG, Bacigalupo A, Malcovati L, Angelucci E, Van Lint MT, et al. Prognostic impact of pre-transplantation transfusion history and secondary iron overload in patients with myelodysplastic syndrome undergoing allogeneic stem cell transplantation: a GITMO study. Haematologica 2010;95:476–84.[CrossRef ] 3. Sucak G, Yegin Z, Özkurt Z, Akı Ş, Yağci M, editors. Iron overload: predictor of adverse outcome in hematopoietic stem cell transplantation. Transplantation proceedings; 2010: Elsevier. [CrossRef ] 4. Kataoka K, Nannya Y, Hangaishi A, Imai Y, Chiba S, Takahashi T, et al. Influence of pretransplantation serum ferritin on nonrelapse mortality after myeloablative and nonmyeloablative allogeneic hematopoietic stem cell transplantation. Biology of Blood and Marrow Transplantation 2009;15:195–204. [CrossRef ] 5. Mahindra A, Bolwell B, Sobecks R, Rybicki L, Pohlman B, Dean R, et al. Elevated pretransplant ferritin is associated with a lower incidence of chronic graft‐versus‐host disease and inferior survival after myeloablative allogeneic haematopoietic stem cell transplantation. British journal of haematology. 2009;146:310–6. [CrossRef ] 6. Pullarkat V, Blanchard S, Tegtmeier B, Dagis A, Patane K, Ito J, et al. Iron overload adversely affects outcome of allogeneic hematopoietic cell transplantation. Bone marrow transplantation 2008;42:799. [CrossRef ] 7. Storey JA, Connor RF, Lewis ZT, Hurd D, Pomper G, Keung YK, et al. The transplant iron score as a predictor of stem cell transplant survival. Journal of Hematology & Oncology 2009;2:44
  3. Chow JK, Werner BG, Ruthazer R, Snydman DR. Increased serum iron levels and infectious complications after liver transplantation. Clinical Infectious Diseases 2010;51:e16–e23
  4. Kontoyiannis DP, Chamilos G, Lewis RE, Giralt S, Cortes J, Raad II, et al. Increased bone marrow iron stores is an independent risk factor for invasive aspergillosis in patients with high‐risk hematologic malignancies and recipients of allogeneic hematopoietic stem cell transplantation. Cancer 2007;110:1303–6
  5. Tachibana T, Tanaka M, Takasaki H, Numata A, Ito S, Watanabe R, et al. Pretransplant serum ferritin is associated with bloodstream infections within 100 days of allogeneic stem cell transplantation for myeloid malignancies. International jou