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Dergiler / Eurasian Journal of Medical Investigation / 2021 / Cilt: 5 - Sayı: 2

Bone Metastases on 18F-FDG PET/CT Imaging in Patients withColorectal Cancer. Does Bone Scintigraphy Still Have a Role?

Sevda Saglampınar KARYAĞAR
Savas KARYAĞAR
Seray SARAÇOĞLU
Binnur Donmez YILMAZ
Sayfa
218–224
Yayın Tarihi
2022-10-12
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

BS is not required for patients who have undergone PET/CT imaging.

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Amaç & Hipotez:Objectives: To analyze the rates, patterns, and features of bone metastases(BM) detected using 18F-FDG PET/CT in pa tients with colorectal cancer(CRC) and compare them with bone scans (BS) in terms of BM detection.
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Temel Bulgular & Veri:Methods: A total of 920 patients with CRC who underwent 18F-FDG PET/CT scans during the period from Jan 2016 toMay 2019 were retrospectively reviewed.
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Sonuç & Katkı:BS is not required for patients who have undergone PET/CT imaging.
🔬Tür:Literatür & Derleme Çalışması
📍Kapsam:2016 Verileri
⚙️Değişkenler:Alan Parametreleri

Abstract

Objectives: To analyze the rates, patterns, and features of bone metastases(BM) detected using 18F-FDG PET/CT in pa tients with colorectal cancer(CRC) and compare them with bone scans (BS) in terms of BM detection. Methods: A total of 920 patients with CRC who underwent 18F-FDG PET/CT scans during the period from Jan 2016 toMay 2019 were retrospectively reviewed. Among these, imaging results were compared for 29 patients who underwentBS within 1 month of 18F-FDG PET/CT. Results: In 38(4.1%) patients, 211 BM were detected on 18F-FDG PET/CT imaging. Of 211 BM detected by PET/CT, 42were osteolytic, 30 were osteoblastic, 55 were mixed, and 84 were CT-negative. Mean SUVmax values of osteoblastic,CT-negative, osteolytic, and mixed lesions were 6.05±2.80, 5.42±2.56, 11.62±6.34 and 8.74±4.48, respectively. A total of126 BM were detected in 16 of 29 patients who underwent both BS and PET/CT imaging. In patient-based evaluation,the sensitivity, specificity and accuracy of PET/CT and BS were 100%,76.92%,89.66% and 93.75%,46.15%,72.41% and inlesion-based evaluation these values were 99.21%,72.73%,97.08% and 52.38%,0%,48.18%, respectively. Conclusion: 18F-FDG PET/CT is a valuable imaging method for detecting BM in colorectal cancer patients, especiallysince it can truly detect CT-negative or isolated BM. BS is not required for patients who have undergone PET/CT imaging.

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Bu Makaleye Atıf Yap

KARYAĞAR, S. S., KARYAĞAR, S., SARAÇOĞLU, S., YILMAZ, B. D. (2022). Bone Metastases on 18F-FDG PET/CT Imaging in Patients withColorectal Cancer. Does Bone Scintigraphy Still Have a Role?. Eurasian Journal of Medical Investigation, Cilt: 5 - Sayı: 2, 218–224. https://ajindex.com/articles/508564

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Kaynakça (14)

  1. Katoh M, Unakami M, Hara M, Fukuchi S. Bone metastasis from colorectal cancer in autopsy cases. J Gastroenterol 1995;30:615–18
  2. Baker LH, Vaitkevicius VK, Figiel SJ. Bony metastasis from adenocarcinoma of colon. Am J Gastroenterol 1974;62:139–44
  3. Besbeas S, Stearns MW. Osseous metastasis from carcinoma of colon and rectum. Dis Colon Rectum 1978;21:266–8
  4. Bonnheim DC, Petrelli NJ, Herrdra L, Walsh D, Mitellman A. Osseous metastasis from colorectal cancer. Am J Surg 1986;151:457–9
  5. Santini D, Tampellini M, Vincenzi B, Ibrahim T, Ortega C, Virzi V, et al. Natural history of bone metastasis in colorectal cancer: final results of a large Italian bone metastases study. Ann Oncol 2012;28:2072–7
  6. Li A, Kasmann L, Rade Ds, Fu C. A scoring system to predict the development of bone metastasis after radical resection of colorectal cancer. Anticancer Res 2017;37:5169–72
  7. Zhenghong ZZ, Guoweijian Z, Caiyunyun YX. Retrospective study of predictors of bone metastasis in colorectal cancer patients. J Bone Oncol 2017;9:25–8
  8. Christensen TD, Jensen SG, Larsen FO, Nielsen DL. Systematic review: Incidence, risk factors, survival and treatment of bone metastases from colorectal cancer. J Bone Oncol 2018;13:97– 105
  9. Baek SJ, Hur H, Min BS, Baik SH, Lee KY, Kim NK. The characteristics of bone metastasis in patients with colorectal cancer: a long-term report from a single ınstitution. World J Surg 2016;40:982–6
  10. Moulton CA, Gu CS, Law CH, Tandan VR, Hart R, Quan D, et al. Effect of PET before liver resection on surgical management for colorectal adenocarcinoma metastases: a randomized clinical trial. JAMA 2014;18:1863–9
  11. Ozis SE, Soydal C, Akyol C, Can N, Kucuk ON, Yagcı C, et al. The role of 18F-fluorodeoxyglucose positron emission tomography/computed tomography in the primary staging of rectal cancer. World J SurgOncol 2014;12:26
  12. Sun L, Guan YS, Pan WM, Luo ZM, Wei JH, Zhao L, et al. Clinical value of 18F-FDG PET/CT in assessing suspicious relapse after rectal cancer resection. World J Gastrointes Oncol 2009;1:55–61
  13. Bashir U, Weeks A, Goda JS, Siddique M, Goh V, Cook GJ. Measurement of 18F-FDG PET tumor heterogeneity improves early assessment of response to bevacizumab compared with the standard size and uptake metrics in a colorectal cancer model. Nucl Med Commun 2019;40:611–7
  14. Van Helden EJ, Vacher YCL, van Wieringen WN, van Velden FHP, Verheul HMW, Hoekstra OS, et al. Radiomics analysis of pre-treatment [18F]FDG PET/CT for pati