Dergiler / Eurasian Journal of Medical Investigation / 2021 / Cilt: 5 - Sayı: 1

Effects of Neutrophil/Monocyte, Neutrophil/Lymphocyte, Neutrophil/Platelet Ratios and C-Reactive Protein Levels on the Mortality and Intensive Care Need of the Patients Diagnosed with Covid-19

Sayfa
21–26
Yayın Tarihi
2022-10-12
DOI
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Among these parameters, it was seen that the best determinant for mortality rate was CRP(cut-off=79.2).Conclusion: It was observed that NLR, NMR, NPR and CRP values were significant in determining the need for intensivecare unit and mortality rate in patients diagnosed with Covid-19.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Objectives: The Covid-19 has been spreading rapidly worldwide.
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Temel Bulgular & Veri:We investigated the effects of some laboratory parameters of patients diagnosed with Covid-19 on admission to the intensive care unit and mortality rate.
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Sonuç & Katkı:Among these parameters, it was seen that the best determinant for mortality rate was CRP(cut-off=79.2).Conclusion: It was observed that NLR, NMR, NPR and CRP values were significant in determining the need for intensivecare unit and mortality rate in patients diagnosed with Covid-19.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Objectives: The Covid-19 has been spreading rapidly worldwide. We investigated the effects of some laboratory parameters of patients diagnosed with Covid-19 on admission to the intensive care unit and mortality rate. We aim to bea reference to other countries with demonstrating the effect of laboratory parameters to prognosis and mortality as acenter from Turkey.Methods: One hundred sixty patients diagnosed with Covid-19 that confirmed with PCR test included the study. Theneutrophil/lymphocyte, neutrophil/monocyte neutrophil/platelet ratios, and C-reactive protein levels were evaluated.Patients were divided into 2 groups; who admitted to intensive care unit and who were treated in Covid-19 inpatientclinic without intensive care need. The groups were statistically compared. Mortality rates were examined to determinea cut-off value for each parameters.Results: These parameters and C-reactive protein levels of the Covid-19 patients were found to be statistically significant in both admission to the intensive care and mortality. The upper limits of these determined cut-off values arepredicted to be critical for admission to intensive care. The cut-off values for NLR, NMR, NPR and CRP for mortality ratewere 9.5, 3.7, 0.022, 79.2. Among these parameters, it was seen that the best determinant for mortality rate was CRP(cut-off=79.2).Conclusion: It was observed that NLR, NMR, NPR and CRP values were significant in determining the need for intensivecare unit and mortality rate in patients diagnosed with Covid-19.

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Bu Makaleye Atıf Yap

BİLGİR, O., AKAN, Ö. Y. (2022). Effects of Neutrophil/Monocyte, Neutrophil/Lymphocyte, Neutrophil/Platelet Ratios and C-Reactive Protein Levels on the Mortality and Intensive Care Need of the Patients Diagnosed with Covid-19. Eurasian Journal of Medical Investigation, Cilt: 5 - Sayı: 1, 21–26. https://ajindex.com/articles/508560

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Kaynakça (13)

  1. Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A Novel Coronavirus from Patients with Pneumonia in China, 2019. N Engl J Med 2020;382:727–33
  2. Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinicalcourse and risk factorsfor mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet 2020;395:1054–62
  3. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel corona virus in Wuhan, China. Lancet 2020;395:497–506
  4. Wang Z, Yang B, Li Q, Wen L, Zhang R. Clinical Features of 69 Cases With Coronavirus Disease 2019 in Wuhan, China. Clin Infect Dis 2020;71:769–77
  5. Zhang JJ, Dong X, Cao YY, Yuan YD, Yang YB, Yan YQ, et al. Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China. Allergy 2020;75:1730–41
  6. Uslu AU, Küçük A, Şahin A, Ugan Y, Yılmaz R, Güngör T, et al. Two new inflammatory markers associated with Disease Activity Score-28 in patients with rheumatoid arthritis: neutrophil-lymphocyte ratio and platelet-lymphocyte ratio. Int J Rheum Dis 2015;18:731–5
  7. Saeed AM, Rosati LM, Narang A, Moningi S, Hacker-Prietz A, Le DT, et al. Elevated absolute monocyte count, absolute neutrophil count, and neutrophil-to-lymphocyte ratio as prognostic factors in locally advanced pancreatic cancer patients treated with stereotactic body radiation therapy. Int J Radiat Oncol Biol Phys 2015;93:E157
  8. Shimoyama Y, Umegaki O, Inoue S, Agui T, Kadono N, Minami T. The Neutrophil to Lymphocyte Ratio Is Superior to Other Inflammation-Based Prognostic Scores in Predicting the Mortality of Patients with Pneumonia. Acta Med Okayama 2018;72:591–3
  9. Jeon Y, Lee WI, Kang SY, Kim MH. Neutrophil-to-MonocytePlus-Lymphocyte Ratio as a Potential Marker for Discriminating Pulmonary Tuberculosis from Nontuberculosis Infectious Lung Diseases. Lab Med 2019;50:286–91
  10. Karagoz I, Yoldas H. Platelet to lymphocyte and neutrophil to lymphocyte ratios as strong predictors of mortality in intensive care population. Revista da Associacao Medica Brasileira 1992;65:633–6
  11. Demir İ, Yücel M. Investigation of relation between mortality of geriatric patients with sepsis and C-Reactive Protein, Procalcitonin and Neutrophil/Lymphocyte ratio in admission to intensive care unit. Fam Pract Palliat Care 2020;5:12–7
  12. Sun ZH. Clinical outcomes of COVID-19 in elderly male patients. J Geriatr Cardiol 2020;17:243–5
  13. Belice T, Demir I, Yüksel A. Role of neutrophil-lymph