Yapay Zeka Hızlı Bakış & Çıkarımlar
AI InsightThis study suggests that viral load is not a reliable parameter in predicting COVID-19 prognosis and mortality.
📌 3 Maddede Bu Makale
Abstract
Objectives: The relationship between the clinical course of COVID-19 and viral load has not been fully elucidated, andconflicting results are still reported. In this study, we aimed to investigate the relationship of initial viral load with clini cal progression and mortality in hospitalized cases. Methods: This study consisted of 218 patients with moderate and severe disease. SARS-CoV-2 cycle threshold (Ct) val ues and positivity were determined in the nasopharyngeal swab samples of the patients by real-time PCR. Results: The mortality rate in hospitalized COVID-19 patients was 15.6%. A weak but significant correlation was foundbetween increasing age and mortality (Spearman's rho: 0.181, p=0.007). The first detected SARS-CoV-2 viral load (Ctvalue) of the patients who were admitted to the clinical and intensive care unit were 29.7 and 27.9, respectively (p=0.07).Initial median viral loads of patients who recovered and died were 29.4 and 28.9, respectively (p=0.44). Conclusion: Initial viral load could not be associated with the severity of the disease and the risk of mortality in moder ate and severe COVID-19 patients. This study suggests that viral load is not a reliable parameter in predicting COVID-19 prognosis and mortality.