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Dergiler / Erciyes Medical Journal / 2021 / Cilt: 43 - Sayı: 1

Serum Level of ADAMTS4 and ADAMTS8 in Patientswith Psoriatic Arthritis

Sevgi İrtegün KANDEMİR
Abdullah Zübeyir DAĞLI
Kemal NAS
Irmak İçen TAŞKIN
Sayfa
20–25
Yayın Tarihi
2022-10-11
DOI
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Results: The results of this study showed that the ADAMTS8 level was significantly elevated in the serum of PsA patients(160.9±49.79 pg/mL) compared to the control groups (

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Objective: Psoriatic arthritis (PsA) is a chronic inflammatory disease associated with psoriasis.
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Temel Bulgular & Veri:The aim of this study was to determine the serum levels ofADAMTS4 and ADAMTS8 in PsA patients.
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Sonuç & Katkı:Results: The results of this study showed that the ADAMTS8 level was significantly elevated in the serum of PsA patients(160.9±49.79 pg/mL) compared to the control groups (
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Objective: Psoriatic arthritis (PsA) is a chronic inflammatory disease associated with psoriasis. A disintegrin and metallopro teinase with thrombospondin motifs (ADAMTS) is a large family of proteoglycanase enzymes that show proteolytic activity.The expression levels of ADAMTS proteases in osteoarthritis and rheumatoid arthritis are upregulated. However, theirexpression levels in PsA patients have not been examined yet. The aim of this study was to determine the serum levels ofADAMTS4 and ADAMTS8 in PsA patients. Materials and Methods: This was a case-control study and enrolled 40 PsA patients and 40 individuals as controls. Serumlevels of ADAMTS4 and ADAMTS8 were examined by the enzyme-linked immunosorbent assay (ELISA). The relationshipbetween ADAMTS8 levels and demographic and clinical features of PsA patients were analyzed. Results: The results of this study showed that the ADAMTS8 level was significantly elevated in the serum of PsA patients(160.9±49.79 pg/mL) compared to the control groups (

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Bu Makaleye Atıf Yap

KANDEMİR, S. İ., DAĞLI, A. Z., NAS, K., TAŞKIN, I. İ. (2022). Serum Level of ADAMTS4 and ADAMTS8 in Patientswith Psoriatic Arthritis. Erciyes Medical Journal, Cilt: 43 - Sayı: 1, 20–25. https://ajindex.com/articles/502289

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Kaynakça (15)

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