Dergiler / Erciyes Medical Journal / 2021 / Cilt: 43 - Sayı: 1

Impaired Renal Function in Outpatients with AcuteCarbon Monoxide Poisoning

Sayfa
13–19
Yayın Tarihi
2022-10-11
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

There was a significant relationshipbetween the follow-up duration of patients with CMP in the emergency department and their CKD-EPI levels (Log-rank/ Mantel–Cox, p

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Amaç & Hipotez:Objective: The study aims to investigate the incidence of early stage kidney disease in outpatients with acute carbon monoxide poisoning (CMP) and to assess whether the Chronic Kidney Disease Epidemiology Collaboration formula (CKD-EPI)values of these patients had any impact on the time taken for their discharge.
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Temel Bulgular & Veri:Materials and Methods: This retrospective case–control study consisted of a total of 94 patients (47 patients with carbonmonoxide poisoning induced by exposure to incompletely burned coal, and 47 age-and sex-matched controls).
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Sonuç & Katkı:There was a significant relationshipbetween the follow-up duration of patients with CMP in the emergency department and their CKD-EPI levels (Log-rank/ Mantel–Cox, p
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Objective: The study aims to investigate the incidence of early stage kidney disease in outpatients with acute carbon monoxide poisoning (CMP) and to assess whether the Chronic Kidney Disease Epidemiology Collaboration formula (CKD-EPI)values of these patients had any impact on the time taken for their discharge. Materials and Methods: This retrospective case–control study consisted of a total of 94 patients (47 patients with carbonmonoxide poisoning induced by exposure to incompletely burned coal, and 47 age-and sex-matched controls). Patient detailsincluding age, CKD-EPI value, hemoglobin, carboxyhemoglobin (COHb), lactate, pH, SaO2, pO2 pCO2, BE, HCO3, glucose,AST, ALT, amylase, ALP, BUN, creatinine, Na, K, Cl, CK, CK-MB, troponin, uric acid levels and duration of follow-upwere recorded. The post-hoc power analysis was calculated using G*Power 3.1.9.2 based on the difference between the twomeans by Wilcoxon–Mann–Whitney test. A Kaplan–Meier survival curve was plotted and test of equality of survival distributions for the different levels of CKD-EPI was compared. Results: The mean age and mean COHb values of the study group were 37.24±12.91 and 21.45±9.89, respectively.The CKD-EPI values were lower in patients belonging to the CMP group (101.39±19.53) compared to the control group(114.92±14.81) (p=0.017), 92% power level, d=0.781, 95% confidence intervals (CI) on the difference between means(-23.01/-4.04). The duration of follow-up of patients with CMP was 29.04±9.7 hours. There was a significant relationshipbetween the follow-up duration of patients with CMP in the emergency department and their CKD-EPI levels (Log-rank/ Mantel–Cox, p

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Bu Makaleye Atıf Yap

GÜNAY, N., GÜNAY, N. E., KALE, A. (2022). Impaired Renal Function in Outpatients with AcuteCarbon Monoxide Poisoning. Erciyes Medical Journal, Cilt: 43 - Sayı: 1, 13–19. https://ajindex.com/articles/502261

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