Dergiler / Erciyes Medical Journal / 2022 / Cilt: 44 - Sayı: 4

Plasma Exchange in the Treatment of A Child with West Nile Virus Encephalitis: A Case Report

Sayfa
430–433
Yayın Tarihi
2022-10-11
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

To our knowledge, this report is the first of a child with WNV infection and SIgAD.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Background: West Nile virus (WNV) is a member of the Japanese encephalitis antigenic complex of the family Flaviviridae that can cause a wide range of clinical symptoms, from asymptomatic disease to severe meningitis, encephalitis flaccid paralysis, and death.
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Temel Bulgular & Veri:Case Report: A 12-year-old boy with selective immunoglobulin A-deficiency (SIgAD) and refractory seizures due to WNV encephalitis (WNE) was successfully treated with therapeutic plasma exchange (TPE) in conjunction with other immunomodulatory therapies.
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Sonuç & Katkı:To our knowledge, this report is the first of a child with WNV infection and SIgAD.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Background: West Nile virus (WNV) is a member of the Japanese encephalitis antigenic complex of the family Flaviviridae that can cause a wide range of clinical symptoms, from asymptomatic disease to severe meningitis, encephalitis flaccid paralysis, and death. In immunocompetent children, WNV infection is usually benign and self-limiting. However, this virus is also associated with severe neurological disease in some patients, especially those who are older, have a chronic disease, have undergone organ transplantation, or are immunocompromised. Case Report: A 12-year-old boy with selective immunoglobulin A-deficiency (SIgAD) and refractory seizures due to WNV encephalitis (WNE) was successfully treated with therapeutic plasma exchange (TPE) in conjunction with other immunomodulatory therapies. Conclusion: WNV can progress like autoimmune encephalitis. TPE appears to be safe and effective for treating children with WNE. To our knowledge, this report is the first of a child with WNV infection and SIgAD.

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Bu Makaleye Atıf Yap

CEYLAN, Ö., ÖZKALE, M., EROL, İ., ÖZKALE, Y. (2022). Plasma Exchange in the Treatment of A Child with West Nile Virus Encephalitis: A Case Report. Erciyes Medical Journal, Cilt: 44 - Sayı: 4, 430–433. https://ajindex.com/articles/502178

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Kaynakça (12)

  1. Soldatou A, Vartzelis G, Vorre S, Papa A, Voudris K, Garoufi A. A toddler with acute flaccıd paralysis due to west nile vırus infection. Pediatr Infect Dis J 2013; 32(9): 1023–24
  2. Spiegel R, Miron D, Gavriel H, Horovitz Y. West Nile virus meningoencephalitis complicated by motor aphasia in Hodgkin’s lymphoma. Arch Dis Child 2002; 86(6): 441–2
  3. Thabet FI, Servinsky SE, Naz F, Kovas TE, Raghib TO. Unusual case of West Nile Virus flaccid paralysis in a 10-year-old child. Pediatr Neurol 2013; 48(5): 393–6
  4. Hindo H, Buescher ES, Frank LM, Pettit D, Dory C, Byrd R. West Nile virus infection in a teenage boy with acute lymphocytic leukemia in remission. J Pediatr Hematol Oncol 2005; 27(12): 659–62
  5. Messacar K, Cree-Green M, Lovell M, Anderson MS, Dominguez SR. Severe neuroinvasive West Nile virus infection in a child with undiagnosed Addison’s disease. IDCases 2014; 1(3): 29–31
  6. Lustig Y, Sofer D, Bucris ED, Mendelson E. Surveillance and diagnosis of West Nile virus in the face of Flavivirus cross-reactivity. Front Microbiol 2018; 9: 2421
  7. Cho H, Diamond MS. Immune responses to West Nile virus infection in the central nervous system. Viruses 2012;4(12):3812–30
  8. Sava M, Bereanu AS. Double filtration plasmapheresis (DFPP) in a patient with west nile virus encephalitis (WNE). AMT 2016; 21(2): 1034
  9. Padmanabhan A, Connelly-Smith L, Aqui N, Balogun RA, Klingel R, Meyer E, et al. Guidelines on the use of therapeutic apheresis in clinical practice - evidence-based approach from the writing committee of the American Society for Apheresis: The eighth special issue. J Clin Apher 2019; 34(3): 171–354
  10. Özkale M, Erol I, Özkale Y, Kozanoğlu İ. Overview of therapeutic plasma exchange in pediatric neurology: a single-centere xperience. Acta Neurol Belg 2018; 118(3): 451–8
  11. Karagianni P, Alexopoulos H, Sourdi A, Papadimitriou D, Dimitrakopoulos AN, Moutsopoulos HM. West Nile Virus infection triggering autoimmune encephalitis: Pathophysiological and therapeutic implications. Clin Immunol 2019; 207: 97–9
  12. Wang N, Shen N, Vyse TJ, Anand V, Gunnarson I, Sturfelt G, et al. Selective IgA deficiency in autoimmune diseases. Mol Med 2011; 17(11-12): 1383–96.