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Dergiler / Clinical and Experimental Health Sciences / 2019 / Cilt: 9 - Sayı: 2

Plasma Nesfatin-1 Levels and its Relationship with Anxiety Levels in Obesity Diagnosed Population: A Controlled Study

Hayriye BAYKAN
Ozgur BAYKAN
Onur DURMAZ
Oguz Elif GULSAH
Hayrettin KARA
Serap AKDENİZ GORGULU
Ali YAMAN
Tunay KARLİDERE
Sayfa
107–111
Yayın Tarihi
2019-06-30
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

No significant differences were found between the obese+anxious group and the obese+nonanxious group.Conclusion: Our results suggest that plasma nesfatin-1 levels are decreased and not associated with anxiety levels in obese populations

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Objective: Nesfatin-1 is a satiety neuropeptide involved in the regulation of metabolic pathways and food intake.
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Temel Bulgular & Veri:Some studies have shown nesfatin-1 to be also associated with stress responses and stress-related behaviors.
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Sonuç & Katkı:No significant differences were found between the obese+anxious group and the obese+nonanxious group.Conclusion: Our results suggest that plasma nesfatin-1 levels are decreased and not associated with anxiety levels in obese populations
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Nesfatin-1 · Obesity · Anxiety

Abstract

Objective: Nesfatin-1 is a satiety neuropeptide involved in the regulation of metabolic pathways and food intake. Some studies have shown nesfatin-1 to be also associated with stress responses and stress-related behaviors. In the present study, we evaluated nesfatin-1 levels in obese individuals and investigated whether nesfatin-1 levels could be associated with anxiety levels in obese populations. Methods: Fifty-eight obese (29 anxious and 29 non-anxious) patients and 25 healthy control subjects between 18 and 65 years old were enrolled in the study. Plasma nesfatin-1 levels were measured with a commercial enzyme-linked immunosorbent assay, and anxiety levels were measured using the Hospital Anxiety and Depression Scale.Results: Plasma nesfatin-1 levels were significantly lower in both obese and anxious subjects and obese and non-anxious subjects than in the control group. No significant differences were found between the obese+anxious group and the obese+nonanxious group.Conclusion: Our results suggest that plasma nesfatin-1 levels are decreased and not associated with anxiety levels in obese populations

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Bu Makaleye Atıf Yap

BAYKAN, H., BAYKAN, O., DURMAZ, O., GULSAH, O. E., KARA, H., GORGULU, S. A., YAMAN, A., KARLİDERE, T. (2019). Plasma Nesfatin-1 Levels and its Relationship with Anxiety Levels in Obesity Diagnosed Population: A Controlled Study. Clinical and Experimental Health Sciences, Cilt: 9 - Sayı: 2, 107–111. https://ajindex.com/articles/481639

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Kaynakça (14)

  1. Stengel A, Mori M, Tache Y. The role of nesfatin-1 in the regulation of food intake and body weight: recent developments and future endeavors. Obes Rev 2013; 14: 859-870
  2. Stengel A, Tache Y. Role of brain NUCB2/nesfatin-1 in the regulation of food intake. Curr Pharm Des 2013; 19: 6955-6959
  3. Maejima Y, Kumamoto K, Takenoshita S, Shimomura K. Projections from a single NUCB2/nesfatin-1 neuron in the paraventricular nucleus to different brain regions involved in feeding. Brain Struct Funct 2016; 221:4723-4731
  4. Stengel A, Hofmann T, Goebel-Stengel M, Lembke V, Ahnis A, Elbelt U, Lamrecht NWG, Ordemann J,Klapp BF, Kobelt P. Ghrelin and NUCB2/nesfatin-1 are expressed in the same gastric cell and differentially correlated with body mass index in obese subjects. Histochem Cell Biol 2013; 139: 909-918
  5. Ramanjaneya M, Addison M, Randeva HS. Possible role of NUCB2/ nesfatin-1 in adipogenesis. Curr Pharm Des 2013; 19: 6976-6980
  6. Ayada C, Toru U, Korkut Y. Nesfatin-1 and its effects on different systems. Hippokratia 2015;19: 4-10
  7. Hofmann T, Ahnis A, Elbelt U, Rose M, Klapp BF, Stengel A. NUCB2/ nesfatin-1 Is Associated with elevated levels of anxiety in anorexia nervosa. PLoS ONE One 10(7): e0132058
  8. Tsuchiya T, Shimizu H, Yamada M, Osaki A, Oh IS, Ariyama Y, Takahashi H,Okada S,Hashimoto K,Satoh T,Kojima M,Mori M. Fasting concentrations of nesfatin-1 are negatively correlated with body mass index in non-obese males. Clin Endocrinol (Oxf) 2010; 73: 484-490
  9. Merali Z, Cayer C, Kent P, Anisman H. Nesfatin-1 increases anxiety – and fear-related behaviors in the rat. Psychopharmacology (Berl) 2008; 201: 115-123
  10. Palasz A, Krzystanek M, Worthington J, Czajkowska B, Kostro K, Wiaderkiewicz R, Bajor G. Nesfatin-1, a unique regulatory neuropeptide of the brain. Neuropeptides 2012; 46: 105-112
  11. Shimizu H, Ohsaki A, Oh IS, Okada S, Mori M. A new anorexigenic protein, nesfatin-1. Peptides 2009; 30: 995-998
  12. Xu YY, Ge JF, Qin G, Peng YN, Zhang CF, Liu XR, Liang LC, Wang ZZ, Chen FH, Li J. Acute, but not chronic, stress increased the plasma concentration and hypothalamic mRNA expression of NUCB2/nesfatin-1 in rats. Neuropeptides 2015; 54: 47-53
  13. Bez Y, Ari M, Ozturk OH, Oktar S, Can Y, Sogut S. Plasma nesfatin-1 level may be associated with disease severity in patients with panic disorder. Bulletin of Clinical Psychopharmacology 2010; 20: 288-292
  14. Bez Y, Ari M, Ozturk OH, Oktar S, Can Y. Increased plasma nesfatin-1 levels in patients w