Dergiler / Balkan Medical Journal / 2018 / Cilt: 35 - Sayı: 2

The Recent Emergence of Clostridium difficile Infection in Romanian Hospitals is Associated with a High Prevalence of Polymerase Chain Reaction Ribotype 027

Sayfa
191–195
Yayın Tarihi
2022-10-11
DOI
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Of 59 isolates, 54 werehighly resistant to moxifloxacin (minimum inhibitory concentration≥32 μg/mL), and the majority were polymerase chain reactionribotype 027 (p

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Amaç & Hipotez:Aims: To investigate the epidemiology of Clostridium difficileinfection in Romanian hospitals.Methods: A survey was conducted at nine hospitals throughoutRomania between November 2013 and February 2014.Results: The survey identified 393 patients with Clostridium difficileinfection.
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Temel Bulgular & Veri:The median age was 67 years (range: 2-94 years); 56% ofpatients were aged >65 years.
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Sonuç & Katkı:Of 59 isolates, 54 werehighly resistant to moxifloxacin (minimum inhibitory concentration≥32 μg/mL), and the majority were polymerase chain reactionribotype 027 (p
🔬Tür:Uygulamalı Anket & Alan Araştırması
📍Kapsam:2013 Verileri
⚙️Değişkenler:Alan Parametreleri

Abstract

Aims: To investigate the epidemiology of Clostridium difficileinfection in Romanian hospitals.Methods: A survey was conducted at nine hospitals throughoutRomania between November 2013 and February 2014.Results: The survey identified 393 patients with Clostridium difficileinfection. The median age was 67 years (range: 2-94 years); 56% ofpatients were aged >65 years. The mean prevalence of Clostridiumdifficile infection was 5.2 cases per 10.000 patient-days. The highestprevalences were 24.9 and 20 per 10.000 patient-days in hospitalsspecializing in gastroenterology and infectious diseases, respectively.Clostridium difficile infections were health care-associated in 70.5%patients and community-acquired in 10.2%. The origin was notdetermined in 19.3%. Clostridium difficile infection was severe in12.3% of patients, and the in-hospital all-cause mortality was 8.8%.Polymerase chain reaction ribotype 027 had the highest prevalence inall participating hospitals and represented 82.6% of the total ribotypedisolates. The minimum inhibitory concentration of moxifloxacin was>4 μg/mL for 59 of 80 tested isolates (73.8%). Of 59 isolates, 54 werehighly resistant to moxifloxacin (minimum inhibitory concentration≥32 μg/mL), and the majority were polymerase chain reactionribotype 027 (p

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Bu Makaleye Atıf Yap

POPESCU, G. A., SERBAN, R., PİSTOL, A., NİCULCEA, A., PREDA, A., LEMENİ, D., MACOVEİ, I. S., T?L?PAN, D., RAFİLA, A., FLOREA, D. (2022). The Recent Emergence of Clostridium difficile Infection in Romanian Hospitals is Associated with a High Prevalence of Polymerase Chain Reaction Ribotype 027. Balkan Medical Journal, Cilt: 35 - Sayı: 2, 191–195. https://ajindex.com/articles/461271

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Kaynakça (12)

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