Dergiler / Atatürk Üniversitesi Veteriner Bilimleri Dergisi / 2020 / Cilt: 15 - Sayı: 3

The Effect of Resveratrol on The Oxidative Stress in Rats Treated with Irradiation

Sayfa
294–300
Yayın Tarihi
2022-10-11
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

As a result of irradiation, a significant increase was found in the level of malondialdehyde (MDA) in the liver, kidney and brain tissues of rats (P

📌 3 Maddede Bu Makale

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Amaç & Hipotez:The antioxidant and protective effect of resveratrol against irradiation induced oxidative damage were researched.
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Temel Bulgular & Veri:Twenty-one rats were seperated into 3 groups; First group was the control group.
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Sonuç & Katkı:As a result of irradiation, a significant increase was found in the level of malondialdehyde (MDA) in the liver, kidney and brain tissues of rats (P
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

The antioxidant and protective effect of resveratrol against irradiation induced oxidative damage were researched. Twenty-one rats were seperated into 3 groups; First group was the control group. Second group was the irradiation group; received physiological saline intraperitoneally (i.p.) for three days, then 9 Gray (Gy) irradiation was applied. Third group was irradiation+Resveratrol group; received 10 mg/kg resveratrol i.p. for three days and then the same dose of radiation was applied. As a result of irradiation, a significant increase was found in the level of malondialdehyde (MDA) in the liver, kidney and brain tissues of rats (P

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Bu Makaleye Atıf Yap

BAYKARA, M., ERİŞİR, M., ÖZÇELİK, M., GÜLER, O., BULMUŞ, F. G. (2022). The Effect of Resveratrol on The Oxidative Stress in Rats Treated with Irradiation. Atatürk Üniversitesi Veteriner Bilimleri Dergisi, Cilt: 15 - Sayı: 3, 294–300. https://ajindex.com/articles/455697

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Kaynakça (13)

  1. Mansour HH., Hafez HF., Fahmy NM., Hanafi N., 2008. Protective effect of N-acetylcysteine against radiation induced DNA damage and hepatic toxicity in rats. Biochem Pharmacol, 75, 773-780
  2. Jagetia GC., Shirwaikar A., Rao SK., Bhilegaonkar PM., 2003. Evaluation of the radioprotective effect of Ageratum conyzoides Linn. extract in mice exposed to different dose of gamma radiation. J Pharm Pharmacol, 55, 1151-1158
  3. Liu Y., Zhang H., Zhang L., Zhou Q., Wang X., Long J., Dong T., Zhao W., 2007. Antioxidant N- acetylcysteine attenuates the acute liver injury caused by X-ray in mice. Eur J Pharmacol, 575, 142-148
  4. Bardak Y., Ozerturk Y., Ozguner F., Durmus M., Delibas N., 2000. Effect of melatonin against oxidative stress in ultraviolet-B exposed rat lens. Curr Eye Res, 20, 225-230
  5. Sies H., 1993. Strategies of antioxidant defense. Eur J Biochem, 215, 213-219
  6. Barker S., Weinfeld M., Zheng J., Li L., Murray D., 2005. Identification of mammalian proteins cross-linked to DNA by ionizing gradiation. J Biol Chem, 280, 33826-33838
  7. Sener TE., Tavukcu HH., Atasoy BM., Cevik O., Kaya OT., Cetinel S., Dagli Degerli A., Tinay I., Simsek F., Akbal C., Buttice S., Sener G., 2018. Resveratrol treatment may preserve the erectile function after radiotherapy by restoring antioxidant defence mechanisms, SIRT1 and NOS protein expressions. Int J Impot Res, 30, 179-188
  8. Bradamante S., Barenghi L., Villa A., 2004. Cardiovascular protective effects of resveratrol. Cardiovasc Drug Rev, 22, 169-188
  9. Velioğlu-Oğünç AI., Sehirli O., Toklu HZ., Ozyurt H., Mayadağli A., Ekşioğlu-Demiralp E., Erzik C., Cetinel S., Yeğen BC., Sener G., 2009. Resveratrol protects against irradiation-induced hepatic and ileal damage via its anti-oxidative activity. Free Radic Res, 43, 1060-1071
  10. Khattab HAH., Abdallah IZA., Yousef FM., Huwait EA., 2017. Efficiency of borage seeds oil against gamma irradiation-induced hepatotoxicity in male rats: possible antioxidant activity. Afr J Tradit Complement Altern Med, 14, 169-179
  11. Radwan RR., Mohamed HA., 2018. Nigella sativa oil modulates the therapeutic efficacy of mesenchymal stem cells against liver injury in irradiated rats. J Photochem Photobiol B, 178, 447-456
  12. Benkovica V., Knezevica AH., Dikica D., Lisicic D., Orsolic N., Basic I., kosalec I., Kopjar N., 2008. Radioprotective effects of propolis and quercetin in gamma-irradiated mice evaluated by the alkaline comet assay. Phytomedicine, 15, 851-858
  13. Placer ZA., Cush