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Dergiler / Archives of epilepsy (Online) / 2022 / Cilt: 28 - Sayı: 2

Antimuscarinic-Induced Convulsions in Fasted Rats after Food Intake: EEG Patterns of Fasting, Scopolamine Treatment, and Convulsions

İhsan KARA
Bilge ÖZERMAN EDİS
Sacit KARAMÜRSEL
Aslı ZENGİN TÜRKMEN
Asiye NURTEN
İlknur ÖZEN
Sayfa
65–77
Yayın Tarihi
2022-10-12
DOI
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Results: These results show that food deprivation for 52 hours decreased the amplitude of the gamma band when compared to basal (P

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Objective: Antimuscarinic treatment in fasted mice and rats causes clonic convulsion soon after food intake.
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Temel Bulgular & Veri:Methods: Male Wistar albino rats were stereotaxically implanted with 10 cortical electrodes, and baseline electroencephalogram recordings were taken for 10 minutes.
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Sonuç & Katkı:Results: These results show that food deprivation for 52 hours decreased the amplitude of the gamma band when compared to basal (P
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Objective: Antimuscarinic treatment in fasted mice and rats causes clonic convulsion soon after food intake. This study was designed to evaluate the electrophysiological markers of these convulsions and fasting in electrocorticograms in rats. Methods: Male Wistar albino rats were stereotaxically implanted with 10 cortical electrodes, and baseline electroencephalogram recordings were taken for 10 minutes. After weighing, rats were deprived of food for 52 hours. At the 24th and 52nd hours of deprivation, continuous electroencephalogram recordings were repeated. After the deprivation period, animals were treated with saline or scopolamine (3 mg/kg). Twenty minutes after injections, animals were given food pellets. After eating food, electroencephalogram recordings were taken for 60 minutes and all animals were observed simultaneously to determine the incidence and onset of convulsions. Results: These results show that food deprivation for 52 hours decreased the amplitude of the gamma band when compared to basal (P

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Bu Makaleye Atıf Yap

KARA, İ., EDİS, B. Ö., KARAMÜRSEL, S., TÜRKMEN, A. Z., NURTEN, A., ÖZEN, İ. (2022). Antimuscarinic-Induced Convulsions in Fasted Rats after Food Intake: EEG Patterns of Fasting, Scopolamine Treatment, and Convulsions. Archives of epilepsy (Online), Cilt: 28 - Sayı: 2, 65–77. https://ajindex.com/articles/447842

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Kaynakça (12)

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