Assessment of risk factors on morbidity and mortality in patients undergoing percutaneous endoscopic gastrostomy

A ≤3.5 cm length of a PEG tube between the gastric mucosa and skin and a low platelet lymphocyte ratio are risk factors for the development of peristomal leakage.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Aim: Percutaneous endoscopic gastrostomy (PEG) is a minimal invasive procedure that is performed in patients who are unable to take oral feeding.

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Temel Bulgular & Veri:Herein, we aimed to assess the risk factors for morbidity and mortality in patients who undergo PEG.Material and Methods: This study was conducted, in a total of 143 patients who underwent PEG for enteral feeding, who were retrospectively analyzed in terms of clinical features, biochemical, hematological and microbiological parameters, and also morbidity and mortality.Results: The study enrolled 140 of 143 consecutive patients who underwent PEG, and a total of 206 interventions were performed.

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Sonuç & Katkı:A ≤3.5 cm length of a PEG tube between the gastric mucosa and skin and a low platelet lymphocyte ratio are risk factors for the development of peristomal leakage.

🔬Tür:Araştırma Makalesi

📍Kapsam:Genişletilmiş Akademik Örneklem

⚙️Değişkenler:Alan Parametreleri

Abstract

Aim: Percutaneous endoscopic gastrostomy (PEG) is a minimal invasive procedure that is performed in patients who are unable to take oral feeding. Herein, we aimed to assess the risk factors for morbidity and mortality in patients who undergo PEG.Material and Methods: This study was conducted, in a total of 143 patients who underwent PEG for enteral feeding, who were retrospectively analyzed in terms of clinical features, biochemical, hematological and microbiological parameters, and also morbidity and mortality.Results: The study enrolled 140 of 143 consecutive patients who underwent PEG, and a total of 206 interventions were performed. The rate of successful insertion was 98.5% (140/142). Complications were peristomal leakage (%29.3), infection due to PEG (9.3%), and tube blockage (6.4%), respectively. In multivariate logistic regression analysis; a ≤ 3.5cm length of the PEG tube between the gastric mucosa and the skin (95% CI: 1.290-33.442 and P= 0.023) and a low platelet lymphocyte ratio (OR = 0.994, 95% CI: 0.989- 0.999 and p = 0.022) were risk factors of peristomal leakage. The 30-day mortality rate was 16%.Discussion: In patient with PEG, the complication rate varies between 5% and 66% according to follow-ups in the literature. The mortality usually depends on the primary disease, and it has been reported between 5% and 20%.Conclusion: PEG is a safe, effective, and minimal invasive procedure. A ≤3.5 cm length of a PEG tube between the gastric mucosa and skin and a low platelet lymphocyte ratio are risk factors for the development of peristomal leakage.

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Bu Makaleye Atıf Yap

TOMAK, Y., AZİRET, M., KARAMAN, K., AKDENİZ, Y., ÇELEBİ, F., YIRGIN, H., ERCAN, M., OTER, V., FIRAT, N., EBİLOĞLU, T. (2022). Assessment of risk factors on morbidity and mortality in patients undergoing percutaneous endoscopic gastrostomy. Annals of Medical Research, Cilt: 25 - Sayı: 3, 400–405. https://ajindex.com/articles/447234

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Kaynakça (9)

Flynn L, Zimmerman LH, McNorton K, Dolman M, Tyburski J, Baylor A, et al. Effects of vitamin D deficiency in critically ill surgical patients. Am J Surg 2011;203(3):379-82.
Higgins DM, Wischmeyer PE, Queensland KM, Sillau SH, Sufit AJ, Heyland DK. Relationship of vitamin d deficiency to clinical out comes in critically ill patients. JPEN J Parenter Enteral Nutr 2012;36(6):713-20.
Braun AB, Gibbons FK, Litonjua AA, Giovannucci E, Christopher KB. Low serum 25-hydroxyvitamin D at critical care initiation is associated with increased mortality. Crit Care Med 2012;40(1):63-72.
Matthews LR, Ahmed Y, Wilson KL, Griggs DD, Danner OK. Worsening severity of vitamin D deficiency is associated with increased length of stay, surgical intensive care unit cost, and mortality rate in surgical intensive care unit patients. Am J Surg 2012;204(1):37-43.
Cecchi A, Bonizzoli M, Douar S, Mangini M, Paladini S, Gazzini B, et al. Vitamin D deficiency in septic patients at ICU admissionis not a mortality predictor. Minerva Anestesiol 2011;77(12):1184-9.
Hu J, Luo Z, Zhao X, Chen Q, Chen Z, Qin H, et al. Changes in the calcium-parathyroid hormone-vitamin d axis and prognosis for critically ill patients: a prospective observational study. PLoS One 2013;8(9):e75441. Joshi A, Bhadade R, Varthakavi PK, DeSouza R, Bhagwat NM, Chadha MD. Vitamin D deficiency is associated with increased mortality in critically ill patients especially in those requiring ventilatory support. Indian J Endocrinol Metab 2014;18(4):511-5. Aird WC: Endothelium as an organ system. Crit Care Med 2004;32(5 Suppl):271-9.
Brock K, Wilkinson M, Cook R, Lee S, Bermingham M. Associations with vitamin D deficiency in “at risk” Australians. J Steroid Biochem Mol Biol 2004;89-90(1- 5):581-8.
Sambrook PN, Cameron ID, Cumming RG, Lord SR, Schwarz JM, Trube A, et al. Vitamin D deficiency is common in frail institutionalised older people in northern Sydney. Med J Aust 2002;176(11):560. Krishnan A, Ochola J, Mundy J, Jones M, Kruger P, Duncan E, et al. Acute fluid shifts influence the assessment of serum vitamin D status in critically ill patients. Crit Care 2010;14(6):R216. Braun A, Chang D, Mahadevappa K, Gibbons FK, Liu Y, Giovannucci E, et al. Association of low serum 25-hydroxyvitamin D levels and mortality in the critically ill. Crit Care Med 2011;39(4):671-7.
Lucidarme O, Messai E, Mazzoni T, Arcade M, du Cheyron D. Incidence and risk factors of vitamin D deficiency in critically ill patients: Results from a prospective