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Dergiler / Annals of Medical Research / 2019 / Cilt: 26 - Sayı: 12

What should be the minimum frequency of micro testicular sperm extraction (m-TESE) in patients with Klinefelter syndrome?

Ahmet SALVACI
Mehmet BALASAR
Sayfa
2957–2960
Yayın Tarihi
2022-10-12
DOI
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Despite the presence of a very limited testicular tissue, it is recommended for this procedure to be performed by expertpractitioners upon discussing very openly the complications and achievements, to decide accordingly and repeat m-TESE in thesepatients where possible.

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Amaç & Hipotez:Aim: To investigate whether a second or even a third surgery is required for sperm retrieval in non-mosaic Klinefelter syndromepatients who underwent a successful/failed micro-testicular sperm extraction (m-TESE).Material and Methods: The patients underwent physical examination, genetic analyses, pathological screening between 2008 and2018.
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Temel Bulgular & Veri:In the patients, sperm retrieval rates, pregnancy after intracytoplasmic sperm injection (ICSI) and baby take-home rates wereexamined.Results: M-TESE was repeated for the second time in thirty-five patients in total, with twenty of that underwent their first m-TESEwith a negative result and fifteen with a positive result.
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Sonuç & Katkı:Despite the presence of a very limited testicular tissue, it is recommended for this procedure to be performed by expertpractitioners upon discussing very openly the complications and achievements, to decide accordingly and repeat m-TESE in thesepatients where possible.
🔬Tür:Araştırma Makalesi
📍Kapsam:2008 Verileri
⚙️Değişkenler:Alan Parametreleri

Abstract

Aim: To investigate whether a second or even a third surgery is required for sperm retrieval in non-mosaic Klinefelter syndromepatients who underwent a successful/failed micro-testicular sperm extraction (m-TESE).Material and Methods: The patients underwent physical examination, genetic analyses, pathological screening between 2008 and2018. In the patients, sperm retrieval rates, pregnancy after intracytoplasmic sperm injection (ICSI) and baby take-home rates wereexamined.Results: M-TESE was repeated for the second time in thirty-five patients in total, with twenty of that underwent their first m-TESEwith a negative result and fifteen with a positive result. In =6/20 patients (30%) who had a negative result with the first m-TESEand in n=9/15 patients (60%) who had a positive result with the first m-TESE, sperm was detected the second time. Pregnancy wasachieved in n=2/6 patients (33%) who were negative the first time and positive the second time. Baby take-home was achieved inone patient (16.6%).Conclusion: In addition to patients from whom sperm could be retrieved previously, sperm could be detected especially in the secondand even third redo m-TESE in patients from whom sperm could not be retrieved. Pregnancy occurred and baby take-home wasachieved. Despite the presence of a very limited testicular tissue, it is recommended for this procedure to be performed by expertpractitioners upon discussing very openly the complications and achievements, to decide accordingly and repeat m-TESE in thesepatients where possible.

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Bu Makaleye Atıf Yap

SALVACI, A., BALASAR, M. (2022). What should be the minimum frequency of micro testicular sperm extraction (m-TESE) in patients with Klinefelter syndrome?. Annals of Medical Research, Cilt: 26 - Sayı: 12, 2957–2960. https://ajindex.com/articles/447086

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Kaynakça (14)

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