Dergiler / Annals of Medical Research / 2019 / Cilt: 26 - Sayı: 4

The effects of mythomycin C, hylan Gf20 and honey combinations on adhesion formation in laparotomized rats

Sayfa
565–569
Yayın Tarihi
2022-10-12
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

But the combinations of these agents do not show any additional effect to decrease adhesion formation.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Aim: Postoperative adhesions are stil unsolved important problems.
📊
Temel Bulgular & Veri:Some studies have been showed that Mitomycine, Hylan GF-20 and honey can decrease adhesion formation.
💡
Sonuç & Katkı:But the combinations of these agents do not show any additional effect to decrease adhesion formation.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Aim: Postoperative adhesions are stil unsolved important problems. Some studies have been showed that Mitomycine, Hylan GF-20 and honey can decrease adhesion formation. This study; was planned to aim to compare the adhesion formation effects of Mitomycin C with Hylan GF-20, Mitomycin C with honey and Hylan GF-20 with honey combinations in the laparotomized rats.Material and Methods: Wistar-Albino 70 malerats, weight range between 180-220 gr, divided into 7 groups. After abrasion formation in the rats’ caecum wall and in the peritoneal surface at the localization of right lower quadrant of anterior abdominal wall, Mitomycin C, Hylan GF-20 and honey combinations used and seven days after operation the abdomen was opened for examination.Results: There were statistically significant differences between control group and the study groups according to adhesion formation scala. In all groups that agents were used adhesion formation was decreased, but when the groups comparing the agents used, there was no statistically significant difference.Conclusion: Mitomycin C, Hylan GF-20 and Honey usage in the laparotomized rats decrease adhesion formation. But the combinations of these agents do not show any additional effect to decrease adhesion formation.

🔖

Bu Makaleye Atıf Yap

CAMCI, C., SARAC, M., İFLAZOĞLU, N., ERGUCUK, H., GURSUL, S. (2022). The effects of mythomycin C, hylan Gf20 and honey combinations on adhesion formation in laparotomized rats. Annals of Medical Research, Cilt: 26 - Sayı: 4, 565–569. https://ajindex.com/articles/447068

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (15)

  1. Jansen RP. Prevention of pelvic peritoneal adhesions. Curr Opin Obstet Gynecol 1991;3:369-74
  2. Avsar AF, Avsar FM, Sahin M, et al. Diphenhydramine and hyaluronic acid derivatives reduce adnexal adhesions and prevent tubal obstructions in rats. Eur J Obstet Gynecol Reprod Biol 2003;106:50-4
  3. Aytekin FO, Tekin K, Kabay B, et al. Role of a hyaluronic-acid derivative in preventing surgical adhesions and abscesses related to dropped bile and gallstones in an experimental model. Am J Surg 2004;188:288-93
  4. Kocaoglu B, Agir I, Nalbantoglu U, et al. Effect of mitomycin-C on post-operative adhesions in tendon surgery: an experimental study in rats. J Bone Joint Surg Br 2010;92:889-93
  5. Aysan E, Ayar E, Aren A, et al. The role of intra-peritoneal honey administration in preventing post-operative peritoneal adhesions. Eur J Obstet Gynecol Reprod Biol 2002;104:152-55
  6. Saber A. Effect of honey versus intergel in intraperitoneal adhesion prevention and colonic anastomotic healing: a randomized controlled study in rats. Int J Surg 2010;8:121-7
  7. Evans DM, McAree K, Guyton DP, et al. Dose dependency and wound healing aspects of the use of tissue plasminogen activator in the prevention of intra-abdominal adhesions. Am J Surg 1993;165:229-32
  8. Hellebrekers BW, Trimbos-Kemper TC, Trimbos JB, et al. Use of fibrinolytic agents in the prevention of postoperative adhesion formation. Fertil Steril 2000;74:203-12
  9. Liakakos T, Thomakos N, Fine PM, et al. Peritoneal adhesions: etiology, pathophysiology, and clinical significance. Recent advances in prevention and management. Dig Surg 2001;18:260-73
  10. Aydin E, Uckan S, Ozdemir BH, et al. Mitomycin C effect on fibrous adhesions of rabbit temporomandibular joint. Otolaryngol Head Neck Surg 2005;133:672-6
  11. Arbag H, Avunduk MC, Ozer B, et al. Increased expression of epidermal growth factor receptors in the tracheal epithelia after topical mitomycin-C in rabbits. Auris Nasus Larynx 2005;32:65-70
  12. Porter GT, Gadre SA, Calhoun KH. The effects of intradermal and topical mitomycin C on wound healing. Otolaryngol Head Neck Surg 2006;135:56-60
  13. Urkan M, Özerhan İH, Ünlü A, et al. Prevention of Intraabdominal Adhesions: An Experimental Study Using Mitomycin-C and 4% Icodextrin. Balkan Med J 2017;34:35-40
  14. Lundorff P, van Geldorp H, Tronstad SE, et al. Reduction of post-surgical adhesions with ferric hyaluronate gel: a European study. Hum Reprod 2001;16:1982-8
  15. DeCherney AH, diZerega GS. Clinical probl