Dergiler / Annals of Medical Research / 2019 / Cilt: 26 - Sayı: 4

The investigation of guillain-barre syndrome and prognosis

Sayfa
763–768
Yayın Tarihi
2022-10-12
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

In our study, age, respiratory failure, cranial nerve involvement and N/L ratio were found as related factors with short-term prognosis.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Aim: Guillain-Barre Syndrome (GBS) is an immune-mediated disease of peripheral nervous system.
📊
Temel Bulgular & Veri:We aimed to determine the subtypes, demographic and clinical characteristics of GBS patients, and the factors affecting the short-term prognosis.Material and Methods: The medical files of 94 patients who were followed up with diagnosis of GBS between January 2011 and January 2018 were retrospectively reviewed.
💡
Sonuç & Katkı:In our study, age, respiratory failure, cranial nerve involvement and N/L ratio were found as related factors with short-term prognosis.
🔬Tür:Literatür & Derleme Çalışması
📍Kapsam:2011 Verileri
⚙️Değişkenler:Alan Parametreleri

Abstract

Aim: Guillain-Barre Syndrome (GBS) is an immune-mediated disease of peripheral nervous system. It is important to estimate the prognosis because of disability burden and morbidity. In addition to clinical features and disease severity scales, serum biomarkers were used to estimate prognosis. We aimed to determine the subtypes, demographic and clinical characteristics of GBS patients, and the factors affecting the short-term prognosis.Material and Methods: The medical files of 94 patients who were followed up with diagnosis of GBS between January 2011 and January 2018 were retrospectively reviewed. Demographic and clinical features, disease severity scores, and neutrophil/lymphocyte (N/L) ratios were determined, and the effects of these parameters on short-term prognosis were investigated.Results: Most of the patients (60.6%) had acute inflammatory demyelinating polyneuropathy (AIDP) subtype. A majority of the cases were men and were in 5 to 7th decades of age. There was no seasonal relevance with the disease. 77% of the cases had albuminocytologic dissociation. The short-term prognosis was associated with age, respiratory failure, cranial nerve involvement and N/L ratio.Conclusion: It is important to estimate the prognosis in GBS. In our study, age, respiratory failure, cranial nerve involvement and N/L ratio were found as related factors with short-term prognosis.

🔖

Bu Makaleye Atıf Yap

SONKAYA, A. R., CEYLAN, M. (2022). The investigation of guillain-barre syndrome and prognosis. Annals of Medical Research, Cilt: 26 - Sayı: 4, 763–768. https://ajindex.com/articles/447065

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (15)

  1. Van den Berg B, Walgaard C, Drenthen J, et al. Guillain - Barré syndrome: pathogenesis, diagnosis, treatment and prognosis. Nat Rev Neuro 2014;10:469-82
  2. Van Doorn PA, Ruts L, Jacobs BC. Clinical features, pathogenesis, and treatment of Guillain-Barré syndrome. Lancet Neurol 2008;7:939-50
  3. Nachamkin I, Arzarte Barbosa P, Ung H, et al. Patterns of Guillain-Barre syndrome in children: results from a Mexican population. Neurology 2007;69:1665-71
  4. McGrogan A, Madle GC, Seaman HE, et al. The epidemiology of Guillain-Barré syndrome worldwide. Neuroepidemiology 2009;32:150-63
  5. Cheng Q, Jiang GX, Press R, et al. Clinical epidemiology of guillain–barré syndrome in adults in sweden 1996–97: a prospective study. Eur J Neurol 2000;7:685-92
  6. Fokkink W-JR, Walgaard C, Kuitwaard K, et al. Association of albumin levels with outcome in intravenous immunoglobulin–treated guillain-barré syndrome. JAMA Neurol 2017;74:189-96
  7. Strauss J, Aboab J, Rottmann M, et al. Plasma cortisol levels in guillain-barré syndrome. Crit Care Med 2009;37:2436-40
  8. Huang Y, Ying Z, Quan W, et al. The clinical significance of neutrophil-to-lymphocyte ratio and monocyte-to-lymphocyte ratio in Guillain–Barré syndrome. Int J Neurosci 2018;128:729-35
  9. Wang Y, Li G, Yang S, et al. Fasting glucose levels correlate with disease severity of Guillain-Barre syndrome. PloS one 2015;10:e014575
  10. Sipilä JO, Kauko T, Soilu-Hänninen M. Admission sodium level and prognosis in adult Guillain–Barré syndrome. Int J Neurosci 2017;127:344-9
  11. Sahin S, Cinar N, Karsidag S. Are cerebrospinal fluid protein levels and plasma neutrophil/lymphocyte ratio associated with prognosis of Guillain Barré syndrome? Neurol Int 2017;9:7032
  12. Hughes R, Newsom-Davis J, Perkin G, et al. Controlled trial of prednisolone in acute polyneuropathy. Lancet Neurol 1978;312:750-3
  13. Lawn ND, Fletcher DD, Henderson RD, et al. Anticipating mechanical ventilation in Guillain-Barré syndrome. Arch Neurol 2001;58:893-8
  14. Compston A. Aids to the investigation of peripheral nerve injuries. Medical Research Council: Nerve Injuries Research Committee. His Majesty’s Stationery Office: 1942; pp. 48 (iii) and 74 figures and 7 diagrams; with aids to the examination of the peripheral nervous system. By Michael O’Brien for the Guarantors of Brain. Saunders Elsevier: 2010; pp.[8] 64 and 94 Figures. Brain 2010;133:2838-44
  15. Vucic S, Kiernan MC, Cornblath DR. Guillain-Barré syndrome: an update. J Clin Neurosci 2009;16:73