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Dergiler / Annals of Medical Research / 2020 / Cilt: 27 - Sayı: 12

Association of Betatrophin, TNF-α and IL-6 with diabetic microvascular and macrovascular complications

Mehmet Ferit GÜRSU
Burkay YAKAR
Erhan ÖNALAN
Nevzat GOZEL
Elif MELEK
Sayfa
3086–3092
Yayın Tarihi
2022-10-12
DOI
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TNF-α levels were higherin patients with both microvascular and macrovascular complications compared to the control group (p

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Amaç & Hipotez:Aim: The most important goal in the treatment of Diabetes Mellitus is to protect patients from micro and macro complications.Inflammatory cytokines and betatrophin have been reported to play a role in diabetic micro and macro complications.
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Temel Bulgular & Veri:This studyaimed to investigate the effect of serum Betatrophin, TNF-α and IL-6 levels on diabetic micro and macro complications in patientswith type 2 Diabetes Mellitus.Materials and Methods: This case-control study was conducted with 91 type 2 Diabetes Mellitus (T2DM) patients betweenJanuary-December 2018.
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Sonuç & Katkı:TNF-α levels were higherin patients with both microvascular and macrovascular complications compared to the control group (p
🔬Tür:Araştırma Makalesi
📍Kapsam:2018 Verileri
⚙️Değişkenler:Alan Parametreleri

Abstract

Aim: The most important goal in the treatment of Diabetes Mellitus is to protect patients from micro and macro complications.Inflammatory cytokines and betatrophin have been reported to play a role in diabetic micro and macro complications. This studyaimed to investigate the effect of serum Betatrophin, TNF-α and IL-6 levels on diabetic micro and macro complications in patientswith type 2 Diabetes Mellitus.Materials and Methods: This case-control study was conducted with 91 type 2 Diabetes Mellitus (T2DM) patients betweenJanuary-December 2018. Case series with 91 patients divided into three groups were included; 31 T2DM patients without diabeticcomplications (group 1=control), 30 patients with diabetic microvascular complications (group 2) and 30 patients with diabeticmacrovasculer complications (group 3). Blood was collected to evaluate biochemical parameters, TNF-α, IL-6 and betatrophin.Results: Betatrophin level was high in patients with renitopathy (p=0.042) and diabetic foot (p=0.036). TNF-α levels were higherin patients with both microvascular and macrovascular complications compared to the control group (p

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Bu Makaleye Atıf Yap

GÜRSU, M. F., YAKAR, B., ÖNALAN, E., GOZEL, N., MELEK, E. (2022). Association of Betatrophin, TNF-α and IL-6 with diabetic microvascular and macrovascular complications. Annals of Medical Research, Cilt: 27 - Sayı: 12, 3086–3092. https://ajindex.com/articles/447029

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Kaynakça (13)

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