Dergiler / Annals of Medical Research / 2020 / Cilt: 27 - Sayı: 9

Comparison of the effects of midazolam and dexmedetomidine on cognitive functions, anxiety and hemodynamics in fiber optic bronchoscopy

Sayfa
2493–2498
Yayın Tarihi
2022-10-12
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

The cognitive functions and anxiety levels both before and after the intervention were similar for thetwo groups.Conclusion: We conclude that dexmedetomidine can be used safely for sedation in fiber optic bronchoscopy and is preferable to midazolam.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Aim: Fiber optic bronchoscopy (FB) is an invasive method used in the diagnosis and treatment of lung diseases.
📊
Temel Bulgular & Veri:We aimed to compare the sedative effects of midazolam and dexmedetomidine in FB, together with their effects on cognitive functions, hemodynamic parameters, and patientsatisfaction and anxiety.Material and Methods: The study includes a total of 80 randomly selected subjects aged ≥ 18 years.
💡
Sonuç & Katkı:The cognitive functions and anxiety levels both before and after the intervention were similar for thetwo groups.Conclusion: We conclude that dexmedetomidine can be used safely for sedation in fiber optic bronchoscopy and is preferable to midazolam.
🔬Tür:Uygulamalı Anket & Alan Araştırması
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Aim: Fiber optic bronchoscopy (FB) is an invasive method used in the diagnosis and treatment of lung diseases. There are several different sedation guidelines for FB, all of which are used by different healthcare providers. We aimed to compare the sedative effects of midazolam and dexmedetomidine in FB, together with their effects on cognitive functions, hemodynamic parameters, and patientsatisfaction and anxiety.Material and Methods: The study includes a total of 80 randomly selected subjects aged ≥ 18 years. The subjects were divided into two groups: midazolam (n = 40) and dexmedetomidine (n = 40). We evaluated treatment outcomes using hemodynamic findings, the Mini-Mental State Examination, the State Anxiety Inventory, and a survey form.Results: The two groups were not significantly different in terms of systolic blood pressure, diastolic blood pressure, mean arterial pressure, heart rate, and peripheral oxygen values. Patient and medical professional satisfaction levels were significantly higher in the dexmedetomidine group. The cognitive functions and anxiety levels both before and after the intervention were similar for thetwo groups.Conclusion: We conclude that dexmedetomidine can be used safely for sedation in fiber optic bronchoscopy and is preferable to midazolam.

🔖

Bu Makaleye Atıf Yap

YAĞCI, İ., PERİNÇEK, G. (2022). Comparison of the effects of midazolam and dexmedetomidine on cognitive functions, anxiety and hemodynamics in fiber optic bronchoscopy. Annals of Medical Research, Cilt: 27 - Sayı: 9, 2493–2498. https://ajindex.com/articles/446579

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (16)

  1. Dasgupta A, Jain P, Minai AO, et al. Utility of transbronchial needle aspiration in the diagnosis of endobronchial lesions. Chest 1999;115:1237-41
  2. Arroliga AC, Matthay R. The role of bronchoscopy in lung cancer. Clin Chest Med 1993;14: 87-99
  3. Yılmaz N, Uçar EY. Fleksibl Bronkoskopide Anestezi: Yeni Yayınlar Ne Öneriyor? Güncel Göğüs Hastalıkları Serisi 2017;5:7-11
  4. Wahidi MM, Jain P, Jantz M, et al. American College of Chest Physicians consensus statement on the use of topical anesthesia, analgesia, and sedation during flexible bronchoscopy in adult patients. Chest 2011;140:1342-50
  5. Jose RJ, Shaefi S, Navani N. Sedation for flexible bronchoscopy: current and emerging evidence. Eyr Respir Rev 2013;22:106-16
  6. Albrecht S, MD, Ihmsen H, Hering W. The effect of age on the pharmacokinetics and pharmacodynamics of midazolam. Clin Pharmacol Ther 1999;65:630-9
  7. Sipe BW, Rex DK, Latinovich D, et al. Propofol versus midazolam/meperidine for outpatient colonoscopy: administration by nurses supervised by endoscopists. Gastrointest Endosc 2002;55:815-25
  8. Ristikankare M, Julkunen R, Laitinen T, et al. Effect of conscious sedation on cardiac autonomic regulation during colonoscopy. Scand J Gastroenterol 2000;35:990-6
  9. Zakko SF, Seifert HA, Gross JB. A comparison of midazolam and diazepam for conscious sedation during colonoscopy in a prospective double- blind study. Gastrointest Endosc 1999;49:684-9
  10. Shelley MP, Wilson P, Norman J. Sedation for fiber optic bronchoscopy. Thorax 1989;44: 769-75
  11. Hall JE, Uhrich TD, Barney JA, et al. Sedative, amnestic, and analgesic properties of smalldose dexmedetomidine infusions. Anesth Analg 2000;90:699-705
  12. Özel-Kızıl ET. Alzheimer hastalığında klinik seyir ve değerlendirme. Psikiyatride Güncel 2013;3:207-15
  13. Folstein MF, Folstein S, Mc Hugh PR. “Mini Mental State” A practical method for grading the cognitive state of patients fort he clinician. Journal of Psychiatric Research 1975;12:189-98
  14. Krueger CE, Kramer JH. Mental status examination. In The Behavioral Neurology of Dementia (ed. B.L. Miller and B.F. Boeve BF), pp.74-84. Cambridge University Press: New York 2009
  15. Güngen C, Ertan T, Eker E, et al. Standardize Mini Mental Test'in Türk toplumunda hafif demans tanısında geçerlik ve güvenilirliği. Türk Psikiyatri Dergisi 2002;13;273-81
  16. Spielberger CD, Gorsuch RL, Lushene RE. Manual for State-Trait Anxiety Inventory. California Consulting Psychologist Pres, Palo Alto, 1970