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Dergiler / Annals of Medical Research / 2020 / Cilt: 27 - Sayı: 1

The effect of amniotic membrane wrapping on colorectal anastomosis in rats undergoing pelvic radiotherapy

Şadiye Mehtat ÜNLÜ
Baha ASLAN
Süleyman Özkan AKSOY
Ali İbrahim SEVİNÇ
Mustafa Cem TERZİ
Hatice ŞİMŞEK KESKİN
Hilmi Feyzi ALANYALI
Sayfa
224–232
Yayın Tarihi
2022-10-12
DOI
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The animals ineach group were anesthetized to assess the clinical, mechanical, histologic, and biochemical parameters of anastomotic healing onthe third and seventh postoperative days.Results: In the third day groups, anastomosis line bursting was observed in only one subject in those undergoing amniotic membranewrapping(p

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Amaç & Hipotez:Aim: This study aimed to investigate the effect of amniotic membrane wrapped onto the anastomosis line following colon resectionand primary anastomosis on anastomosis healing in rats undergoing pelvic radiotherapy.Material and Methods: Fifty-six male Wistar albino rats were randomly allocated to four main groups.
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Temel Bulgular & Veri:Radiotherapy was administered under general anesthesia eight and four days prior to surgeryat a total of 20 Gy.
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Sonuç & Katkı:The animals ineach group were anesthetized to assess the clinical, mechanical, histologic, and biochemical parameters of anastomotic healing onthe third and seventh postoperative days.Results: In the third day groups, anastomosis line bursting was observed in only one subject in those undergoing amniotic membranewrapping(p
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Aim: This study aimed to investigate the effect of amniotic membrane wrapped onto the anastomosis line following colon resectionand primary anastomosis on anastomosis healing in rats undergoing pelvic radiotherapy.Material and Methods: Fifty-six male Wistar albino rats were randomly allocated to four main groups. Group I, left colon resection andprimary anastomosis; Group II, post-anastomotic amniotic membrane; Group III, preoperative radiotherapy; Group IV, preoperativeradiotherapy and amniotic membrane. Radiotherapy was administered under general anesthesia eight and four days prior to surgeryat a total of 20 Gy. In the first operation, all the rats underwent 1 cm left colon resection and primary anastomosis. The animals ineach group were anesthetized to assess the clinical, mechanical, histologic, and biochemical parameters of anastomotic healing onthe third and seventh postoperative days.Results: In the third day groups, anastomosis line bursting was observed in only one subject in those undergoing amniotic membranewrapping(p

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Bu Makaleye Atıf Yap

ÜNLÜ, Ş. M., ASLAN, B., AKSOY, S. Ö., SEVİNÇ, A. İ., TERZİ, M. C., KESKİN, H. Ş., ALANYALI, H. F. (2022). The effect of amniotic membrane wrapping on colorectal anastomosis in rats undergoing pelvic radiotherapy. Annals of Medical Research, Cilt: 27 - Sayı: 1, 224–232. https://ajindex.com/articles/446450

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Kaynakça (15)

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