Dergiler / Annals of Medical Research / 2021 / Cilt: 28 - Sayı: 6

Is neutrophil/lymphocyte and platelet/lymphocyte ratioa predictive factor for the fibrous stage in patients withchronic hepatitis B?

Sayfa
1134–1138
Yayın Tarihi
2022-10-12
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

In advanced fibrosis group, liver function tests and bilirubin levels were significantly higher and albumin levelwas significantly lower (p

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Aim: Neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) are an inexpensive inflammatory marker that can beeasily obtained from the blood count and can be used in many chronic diseases.
📊
Temel Bulgular & Veri:Materials and Methods: 173 patients with chronic HBV were included in the study.
💡
Sonuç & Katkı:In advanced fibrosis group, liver function tests and bilirubin levels were significantly higher and albumin levelwas significantly lower (p
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Aim: Neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) are an inexpensive inflammatory marker that can beeasily obtained from the blood count and can be used in many chronic diseases. In our study, we aimed to investigate the relationshipbetween fibrosis stage and NLR, PLR in patients with chronic hepatitis B virus (HBV). Materials and Methods: 173 patients with chronic HBV were included in the study. The demographic data and hemogram parameters ofall patients were recorded. Histopathological data of the patients were documented. Accompanying comorbid diseases, medicationsand previous operations were questioned. In chronic HBV patients, fibrosis level was compared with hematological parameters. Results: A total of 173 patients, 100 (57.8%) of whom were male, were included in the study. As a result of the liver biopsy; mildfibrosis (steage/1-2) in 83(47.9%) patients, moderate fibrosis (steage/3-4) in 35(20.3%) patients and advanced fibrosis (stage/5-6)in 55(31.8%) patients. In advanced fibrosis group, liver function tests and bilirubin levels were significantly higher and albumin levelwas significantly lower (p

🔖

Bu Makaleye Atıf Yap

ÖZKAHRAMAN, A., KAYAR, Y., SÜRMELİ, N., KONĞR, Ş., DERTLİ, R. (2022). Is neutrophil/lymphocyte and platelet/lymphocyte ratioa predictive factor for the fibrous stage in patients withchronic hepatitis B?. Annals of Medical Research, Cilt: 28 - Sayı: 6, 1134–1138. https://ajindex.com/articles/446253

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (14)

  1. Lavanchy D. Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures. J Viral Hepat 2004
  2. 2Fattovich G, Bortolotti F, Donato F. Natural history of chronic hepatitis B: special emphasis on disease progression and prognostic factors. J Hepatol 2008
  3. 52 3. Siddique I, El-Naga HA, Madda JP, et al. Sampling variability on percutaneous liver biopsy in patients with chronic hepatitis C virus infection. Scand J Gastroenterol 2003
  4. Hui AY, Chan HL, Wong VW, et al. Identification of chronic hepatitis B patients without significant liver fibrosis by a simple noninvasive predictive model. Am J Gastroenterol 2005
  5. Yilmaz B, Aydin H, Can G, et al. The relationship between fibrosis level and blood neutrophil to lymphocyte ratio in inactive hepatitis B carriers. Eur J Gastroenterol Hepatol 2014
  6. Kim H, Ro SM, Yang JH, et al.The neutrophiltolymphocyte ratio prechemotherapy and postchemotherapy as a prognostic marker in metastatic gastric cancer Korean J Intern Med 2018
  7. Walsh SR, Cook EJ, Goulder F, et al. Neutrophillymphocyte ratio as a prognostic factor in colorectal cancer. J Sur Oncol. 2005
  8. Alkhouri N, Tamimi TA, Yerian L, et al. The inflamed liver and atherosclerosis: a link between histologic severity of nonalcoholic fatty liver disease and increased cardiovascular risk. Dig Dis Sci 2010
  9. Kekilli M, Tanoglu A, Sakin YS, et al. Is the neutrophil to lymphocyte ratio associated with liver fibrosis in patients with chronic hepatitis B?. World J Gastroenterol 2015
  10. Ates I, Bulut M, Ozkayar N, et al. Association between high platelet indices and proteinuria in patients with hypertension. Ann Lab Med 2015
  11. Coskun BDO, Dizdar OS, Baspınar O, et al. Usefulness of the neutrophil-to-lymphocyte ratio and platelet morphologic parameters in predicting hepatic fibrosis in chronic hepatitis c patients. Ann Clin Lab Sci 2016
  12. Hendra TJ, Oswald GA, Yudkin JS. Increased mean platelet volüme after acute myocardial infarction relates to diabetes and to cardiac failure. Diabetes Res Clin Pract 1988
  13. Rodak AP, Kiciak S, Tomasiewicz K. Neutrophillymphocyte ratio and mean platelet volume as predictive factors for liver fibrosis and steatosis in patients with chronic hepatitis B. Ann Agric Environ Med. 2018
  14. Atay K. Relationship between neutrophil-tolymphocyte ratio, mean