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Dergiler / Turkish Thoracic Journal / 2016 / Cilt: 17 - Sayı: 1

New-Onset Sarcoidosis After Remission of Cushing’s Syndrome

ALEV SELEK
SERAP ARGUN BARIŞ
Berrin ÇETİNASLAN
Zeynep CANTÜRK
İlhan TARKUN
Zeynep AKYAY
Sayfa
36–38
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

However, the disease became apparent after the reduction of cortisol levels following the treatment of CS

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Exposure to high levels of endogenous or exogenous glucocorticoids suppresses the infl ammatory response genes.
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Temel Bulgular & Veri:Here, we report a 27-year-old female patient who was recently diagnosed with sarcoidosis after remission of CS.
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Sonuç & Katkı:However, the disease became apparent after the reduction of cortisol levels following the treatment of CS
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Exposure to high levels of endogenous or exogenous glucocorticoids suppresses the infl ammatory response genes. Excessive endogenous hypercortisolism may mask the active inflammatory diseases. Rebound immune modulation may occur after Cushing’s syndrome (CS) remission, leading to the new onset of autoimmune diseases. Here, we report a 27-year-old female patient who was recently diagnosed with sarcoidosis after remission of CS. Normal thorax imaging showed that the patient was free of disease during the course of CS and without any symptoms of sarcoidosis. After complete remission of CS, she was diagnosed with sarcoidosis based on clinical and radiological evidence. Excessive hypercortisolism may suppress the active inflammatory stage of sarcoidosis. However, the disease became apparent after the reduction of cortisol levels following the treatment of CS

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Bu Makaleye Atıf Yap

SELEK, A., BARIŞ, S. A., ÇETİNASLAN, B., CANTÜRK, Z., TARKUN, İ., AKYAY, Z. (2016). New-Onset Sarcoidosis After Remission of Cushing’s Syndrome. Turkish Thoracic Journal, Cilt: 17 - Sayı: 1, 36–38. https://ajindex.com/articles/418145

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  1. Nieman LK, Biller BM, Findling JW, et al. The diagnosis of Cushing’s syndrome: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab 2008;93:1526-40. [CrossRef] 2. Da Mota F, Murray C, Ezzat S. Overt immune dysfunction after Cushing’s syndrome remission: a consecutive case series and review of the literature. J Clin Endocrinol Metab 2011;96:1670-4. [CrossRef] 3. Amin EN, Closser DR, Crouser ED. Current best practice in the management of pulmonary and systemic sarcoidosis. Ther Adv Respir Dis 2014;8:111-32. [CrossRef] 4. Nunes H, Brillet PY, Valeyre D, et al. Imaging in sarcoidosis. Semin Respir Crit Care Med 2007;28:102-20. [CrossRef] 5. Doppman JL, Oldfield EH, Chrousos GP, et al. Rebound thymic hyperplasia after treatment of Cushing’s syndrome. AJR Am J Roentgenol 1986;147:1145-7. [CrossRef] 6. Swearingen B, Biller BM, Barker 2nd FG, et al. Long-term mortality after transsphenoidal surgery for cushing disease. Ann Intern Med 1999;130:821-4. [CrossRef] 7. Ntali G, Asimakopoulou A, Siamatras T, et al. Mortality in Cushing’s syndrome: systematic analysis of a large series with prolonged follow-up. Eur J Endocrinol 2013;169:715-23. [CrossRef] 8. Mc Gregor AM. Immunoendocrine interactions and autoimmunity. N Engl J Med 1990;322:1739-41. [CrossRef] 9. Dimeloe S, Nanzer A, Ryanna K, Hawrylowicz C. Regulatory T cells, inflammation and the allergic response-The role of glucocorticoids and Vitamin D. J Steroid Biochem Mol Biol 2010;120:86-9. [CrossRef] 10. Schaefer S, Meyer S, Brueck CC, et al. Sarcoidosis following Cushing’s syndrome: A report of two cases and review of the literature. Exp Clin Endocrinol Diabetes 2010;118:147-50. [CrossRef]