KaydedilenlerDerginizi ekleyin

Dergiler / Turkish Thoracic Journal / 2021 / Cilt: 22 - Sayı: 5

Fetal Programming: Lung Health and Disease

Ozge YİLMAZ
HASAN YÜKSEL
A Sonia BUİST
Sayfa
413–417
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

In this review, we describe the normal development of the lungs and the major factors that may influence lung growth and development with the potential for sequelae into adult life.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Fetal programming is a mechanism whereby stimuli acting on the developing fetus influence the development of the fetus in a way that may set the stage for adult health and disease.
📊
Temel Bulgular & Veri:These stimuli may be environmental, such as maternal smoking; metabolic, such as the maternal diet and nutrition; or endocrine, such as diabetes or stress, and may extend over several generations.
💡
Sonuç & Katkı:In this review, we describe the normal development of the lungs and the major factors that may influence lung growth and development with the potential for sequelae into adult life.
🔬Tür:Literatür & Derleme Çalışması
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Fetal programming is a mechanism whereby stimuli acting on the developing fetus influence the development of the fetus in a way that may set the stage for adult health and disease. These stimuli may be environmental, such as maternal smoking; metabolic, such as the maternal diet and nutrition; or endocrine, such as diabetes or stress, and may extend over several generations. The endocrine system influences fetal programming with effects of insulin, thyroid hormones, and glucocorticoid hormones. Epigenetic information may be modified by DNA methylation, histone modifications, and micro RNAs due to environmental exposures. In this review, we describe the normal development of the lungs and the major factors that may influence lung growth and development with the potential for sequelae into adult life.

🔖

Bu Makaleye Atıf Yap

YİLMAZ, O., YÜKSEL, H., BUİST, A. S. (2021). Fetal Programming: Lung Health and Disease. Turkish Thoracic Journal, Cilt: 22 - Sayı: 5, 413–417. https://ajindex.com/articles/418106

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (1)

  1. Barker DJP. In-utero programming of chronic disease. Clin Sci. 1998;95(2):115-128. [CrossRef] 2. Maritz GS, Harding R. Life-long programming implications of exposure to tobacco smoking and nicotine before and soon after birth: evidence for altered lung development. Int J Environ Res Public Health. 2011;8(3):875-898. [CrossRef] 3. Kwon EJ, Kim YJ. What is fetal programming?: a lifetime health is under the control of in utero health. Obstet Gynecol Sci. 2017;60(6):506-519. [CrossRef] 4. Perrone S, Santacroce A, Picardi A, Buonocore G. Fetal programming and early identification of newborns at high risk of free radical-mediated diseases. World J Clin Pediatr. 2016;5(2):172-181. [CrossRef] 5. Barker DJ, Martyn CN. The maternal and fetal origins of cardiovascular disease. J Epidemiol Commun Health. 1992;46(1):8- 11. [CrossRef] 6. Azad MB, Moyce BL, Guillemette L et al. Diabetes in pregnancy and lung health in offspring: developmental origins of respiratory disease. Paediatr Respir Rev. 2017;21:19-26. [CrossRef] 7. Fowden AL, Forhead AJ. Endocrine mechanisms of intrauterine programming. Reproduction. 2004;127(5):515-526. [CrossRef] 8. Singh S, Bodas M, Bhatraju NK et al. Hyperinsulinemia adversely affects lung structure and function. Am J Physiol Lung Cell Mol Physiol. 2016;310(9):L837-L845. [CrossRef] 9. Epaud R, Aubey F, Xu J et al. Knockout of insulin-like growth factor-1 receptor impairs distal lung morphogenesis. PLoS ONE. 2012;7(11):e48071. [CrossRef] 10. Li J, Masood A, Yi M et al. The IGF-I/IGF-R1 pathway regulates postnatal lung growth and is a nonspecific regulator of alveologenesis in the neonatal rat. Am J Physiol Lung Cell Mol Physiol. 2013;304(9):L626-L637. [CrossRef] 11. White V, Jawerbaum A, Mazzucco MB, et al. Diabetes-associated changes in the fetal insulin/insulin-like growth factor system are organ specific in rats. Pediatr Res. 2015;77(1):48-55. [CrossRef] 12. Han RN, Post M, Tanswell AK, Lye SJ. Insulin-like growth factor-I receptor-mediated vasculogenesis/angiogenesis in human lung development. Am J Respir Cell Mol Biol. 2003;28(2):159-169. [CrossRef] 13. Dehmel S, Nathan P, Bartel S, et al. Intrauterine smoke exposure deregulates lung function, pulmonary transcriptomes, and in particular insulin-like growth factor (IGF)-1 in a sex-specific manner [sci rep.:7547]. Sci Rep. 2018;8(1):7547. [CrossRef] 14. Patel J, Landers K, Li H, Mortimer RH, Richard K. Delivery of maternal thyroid hormones to the fetus. Trends Endocrinol Metab. 2011;22(5