Dergiler / Retina-Vitreus / 2021 / Cilt: 30 - Sayı: 1

Neutrophil-Lymphocyte Ratio in Patients with Retinitis Pigmentosa Patients

Sayfa
61–63
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Further studies are needed in order to come up to more defi nite results.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Purpose: Intraocular infl ammation in RP eyes, which might be related to its pathophysiology.To evaluate the neutrophil to lymphocyte ratio (NLR) in patients with retinitis pigmentosa and to compare with this the control group.
📊
Temel Bulgular & Veri:Materials and Methods: This retrospective study included 31 patients with retinitis pigmentosa and 25 healthy subjects.
💡
Sonuç & Katkı:Further studies are needed in order to come up to more defi nite results.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Purpose: Intraocular infl ammation in RP eyes, which might be related to its pathophysiology.To evaluate the neutrophil to lymphocyte ratio (NLR) in patients with retinitis pigmentosa and to compare with this the control group. Materials and Methods: This retrospective study included 31 patients with retinitis pigmentosa and 25 healthy subjects. Complete ophthalmological examination and complete blood count measurement results of all subjects were evaluated. The NLR was calculated in all of the individuals and compared between the retinitis pigmentosa patients and the healthy controls. Results: The mean NLR±SD was 2.46±1.01 in the retinitis pigmentosa patients group. The mean NLR±SD was 1.87±0.58 in the control group. There was a signifi cant difference in NLR between retinitis pigmentosa and control groups (p=0.003). Conclusion: NLR could be considered a quicker and a cheaper marker detected only routine CBC analysis an infl ammatory marker for retinitis pigmentosa patients. Further studies are needed in order to come up to more defi nite results.

🔖

Bu Makaleye Atıf Yap

ERTAN, E., REŞAT, D., RAHMİ, D. (2021). Neutrophil-Lymphocyte Ratio in Patients with Retinitis Pigmentosa Patients. Retina-Vitreus, Cilt: 30 - Sayı: 1, 61–63. https://ajindex.com/articles/413572

Kaynakça (13)

  1. Daiger SP, Sullivan LS, Bowne SJ. Genes and mutations causing retinitis pigmentosa. Clin Genet 2013;84:132-41
  2. Hartong DT, Berson EL, Dryja TP. Retinitis pigmentosa. Lancet 2006;368:1795-809
  3. Daiger SP, Bowne SJ, Sullivan LS. Genes and mutations causing autosomal dominant retinitis pigmentosa. Cold Spring Harb Perspect Med 2014;10:5
  4. Haim M. Epidemiology of retinitis pigmentosa in Denmark. Acta Ophthalmol Scand Suppl 2002;233:1-34
  5. Fariss RN, Li ZY, Milam AH. Abnormalities in rod photoreceptors,amacrine cells, and horizontal cells in human retinas with retinitis pigmentosa. Am J Ophthalmol 2000;129:215-23
  6. Newsome D. A. Michels R. G. Detection of lymphocytes in the vitreous gel of patients with retinitis pigmentosa. Am J Ophthalmo 1988;l105:596-602
  7. Yoshida N, Ikeda Y, Notomi S, et al. Laboratory evidence of sustained chronic infl ammatory reaction in retinitis pigmentosa. Ophthalmology 2013;120:e5-12
  8. Yoshida N, Ikeda Y, Notomi S, et al. Clinical evidence of sustained chronic infl ammatory reaction in retinitis pigmentosa. Ophthalmology2013;120:100-5
  9. Akil E, Bulut A, Kaplan I, et al. The increase of carcino embryonic antigen (CEA), high-sensitivity C-reactive protein, and neutrophil/lymphocyte ratio in Parkinson’s disease. Neurol Sci. 2015;36:423-2
  10. Dirican N, Anar C, Kaya S, et al. The clinical signifi cance of hematologic parameters in patients with sarcoidosis. Clin Respir J. 2016;10:32-9
  11. Karaca EE, Özmen MC, Ekici F, et al. Neutrophil-to-lymphocyte ratio may predict progression in patients with keratoconus. Cornea. 2014;33:1168-73 12- Ozgonul C, Sertoglu E, Mumcuoglu T, et al. Prediction of Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma by Using Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio.Ocul Immunol Infl amm. 2016;24:665-70
  12. Ilhan N, Daglioglu MC, Ilhan O, et al. Assessment of neutrophil/ lymphocyte ratio in patients with age-related macular degeneration. Ocul Immunol Infl amm 2014:1-4
  13. Dursun A, Ozturk S, Yucel H, et al. Association of neutrophil/ lymphocyte ratio and retinal vein occlusion.Eur J Ophthalmol 2015; 25:343-6 15- Murakami Y, Yoshida N, Ikeda Y, et al. Relationship between aqueous fl are and visual function in retinitis pigmentosa. Am J Ophthalmol. 2015;159: 958-63.