Dergiler / Perinatoloji Dergisi / 2020 / Cilt: 28 - Sayı: 3

Preterm erken membran rüptürü olan olgularda koryoamniyonit tan›s›nda C-reaktif protein ve prokalsitonin önemi

The importance of C-reactive protein and procalcitonin in the diagnosis of chorioamnionitis in the cases with preterm premature rupture of membranes

Sayfa
190–195
DOI
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Bulgular: Koryoamniyonit tan›s› alan olgular›n do¤um s›ras›ndaki WBC, CRP ve prokalsitonin ortalamas› ve yat›fl s›ras›ndaki prokalsitonin ortalama de¤eri koryoamniyonit tan›s› almayan gruptan anlaml› olarak daha yüksekti.

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Amaç & Hipotez:ile klini¤imize yatan hastalardan klinik koryoamniyonit geliflen ve geliflmeyen olgular›n klinik biyokimyasal belirteçlerini karfl›laflt› rmakt›r.
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Temel Bulgular & Veri:Yöntem: Çal›flmaya Mersin Üniversitesi T›p Fakültesi Kad›n Hastal› klar› ve Do¤um Klini¤ine PEMR ön tan›s› ile yat›r›larak takip ve tedavi edilen 81 tekil gebeli¤i olan olgular al›nd›.
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Sonuç & Katkı:Bulgular: Koryoamniyonit tan›s› alan olgular›n do¤um s›ras›ndaki WBC, CRP ve prokalsitonin ortalamas› ve yat›fl s›ras›ndaki prokalsitonin ortalama de¤eri koryoamniyonit tan›s› almayan gruptan anlaml› olarak daha yüksekti.
🔬Tür:Araştırma Makalesi
📍Kapsam:48 hasta
⚙️Değişkenler:Alan Parametreleri

Özet

ile klini¤imize yatan hastalardan klinik koryoamniyonit geliflen ve geliflmeyen olgular›n klinik biyokimyasal belirteçlerini karfl›laflt› rmakt›r. Bu amaçla klinik koryoamniyonit tan›s›nda enfeksiyon belirteçlerinin ortalama de¤erlerinin anlaml›l›k düzeyi, duyarl›l›közgüllükleri ve ayr›ca bu belirteçlerin birbirleri ile olan korelasyonlar› araflt›r›ld›. Yöntem: Çal›flmaya Mersin Üniversitesi T›p Fakültesi Kad›n Hastal› klar› ve Do¤um Klini¤ine PEMR ön tan›s› ile yat›r›larak takip ve tedavi edilen 81 tekil gebeli¤i olan olgular al›nd›. Klinik koryoamniyonit geliflen olgular ve geliflmeyen 48 hastan›n de¤erleri karfl›laflt›- r›ld›. Bulgular: Koryoamniyonit tan›s› alan olgular›n do¤um s›ras›ndaki WBC, CRP ve prokalsitonin ortalamas› ve yat›fl s›ras›ndaki prokalsitonin ortalama de¤eri koryoamniyonit tan›s› almayan gruptan anlaml› olarak daha yüksekti. Sonuç: PEMR tan›s› ile takip edilen olgularda hasta yat›fl›ndaki prokalsitonin ve do¤um zaman›ndaki WBC, serum CRP ve prokalsitoninin klinik koryoamniyonit olgular›nda önemli oldu¤u görüldü. Çal›flmam›zdan bu enfeksiyon belirteçlerinin sadece hastan› n yat›fl› s›ras›nda de¤il hasta takibinde de düzenli aral›klarla bak› larak koryoamniyonitin erken tan›s›nda kullan›labilece¤i (özellikle prokalsitonin) sonucuna var›ld›.

Abstract

Objective: Our aim is to compare the clinical biochemical markers of the cases who developed and did not develop clinical chorioamnionitis among those hospitalized in our clinic with the diagnosis of preterm premature rupture of membranes (PPROM). For that purpose, we investigated the significance levels of mean values, sensitivity and specificity levels of the infection markers and also their correlations with each other in the diagnosis of clinical chorioamnionitis. Methods: Eighty-one cases with singleton pregnancy who were hospitalized with the pre-diagnosis of PPROM and followed up and treated in the Clinic of Gynecology and Obstetrics of the Faculty of Medicine at Mersin University were included in the study. The values of 48 cases who developed and did not develop clinical chorioamnionitis were compared. Results: The mean WBC, CRP and procalcitonin values at labor and mean procalcitonin values at hospitalization were significantly higher in the cases diagnosed with chorioamnionitis than the cases without chorioamnionitis diagnosis. Conclusion: We found out that the procalcitonin values at hospitalization and WBC, serum CRP and procalcitonin values at labor in the cases followed up with the diagnosis of PPROM were significant in clinical chorioamnionitis cases. We concluded in our study that these infection markers (procalcitonin in particular) can be used in the early diagnosis of chorioamnionitis by not checking at hospitalization only but also in the follow-ups of the patients regularly.

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Bu Makaleye Atıf Yap

TAŞIN, C., COFLKUN, A. (2020). Preterm erken membran rüptürü olan olgularda koryoamniyonit tan›s›nda C-reaktif protein ve prokalsitonin önemi. Perinatoloji Dergisi, Cilt: 28 - Sayı: 3, 190–195. https://ajindex.com/articles/413547

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  1. Mercer BM. Preterm premature rupture of the membranes: current approaches to evaluation and management. Obstet Gynecol Clin North Am 2005;32:411–28. [PubMed] [CrossRef] 2. Tsakiridis I, Mamopoulos A, Chalkia-Prapa EM, Athanasiadis A, DagklisT. Preterm premature rupture of membranes: a review of 3 national guidelines. Obstet Gynecol Surv 2018;73: 368–75. [PubMed] [CrossRef] 3. Committee on Practice Bulletins-Obstetrics. ACOG practice bulletin no. 188: Pre labor rupture of membranes. Obstet Gynecol 2018;131:e1–e14. [PubMed] [CrossRef] 4. Kenyon S, Boulvain M, Neilson JP. Antibiotics for preterm rupture of membranes. Cochrane Database Syst Rev 2013;(12):CD001058. [PubMed] [CrossRef] 5. Seliem W, Sultan AM. Presepsin as a predictor of early onset neonatal sepsis in the umbilical cord blood of premature infants with premature rupture of membranes. Pediatr Int 2018;60: 428–32. [PubMed] [CrossRef] 6. Tita AT, Andrews WW. Diagnosis and management of clinical chorioamnionitis. Clin Perinatol 2010;37:339–54. [PubMed] [CrossRef] 7. Yoon BH, Romero R, Park JS, Kim CJ, Kim SH, Choi JH, et al. Fetal exposure to an intra-amniotic inflammation and the development of cerebral palsy at the age of three years. Am J Obstet Gynecol 2000;182:675–81. [PubMed] [CrossRef] 8. Newton ER. Chorioamnionitis and intraamniotic infection. Clin Obstet Gynecol 1993;36:795–808. [PubMed] [CrossRef] 9. Czikk MJ, McCarthy FP, Murphy KE. Chorioamnionitis: from pathogenesis to treatment. Clin Microbiol Infect 2011; 17:1304–11. [PubMed] [CrossRef] 10. Practice Bulletins No. 139: Premature rupture of membranes. Obstet Gynecol 2013;122:918–30. [PubMed] [CrossRef] 11. Çakar E, Çakar fiE, Taflan HA, Karçaalt›ncaba D, fientürk MB, Koç N, et al. Diagnostic and prognostic value of presepsin for subclinical chorioamnionitis in pregnancies between 23–28 week with preterm premature rupture of the membranes. Balkan Med J 2016;33:668–74. [PubMed] [CrossRef] 12. Thornburg LL, Queenan R, Brandt-Griffith B, Pressman EK. Procalcitonin for prediction of chorioamnionitis in preterm premature rupture of membranes. J Matern Fetal Neonatal Med 2016;29:2056–61. [PubMed] [CrossRef] 13. Arias R, Tomich P. Etiology and outcome of low birth weight and preterm infants. Obstet Gynecol 1982;60:277–81. [PubMed] 14. ACOG Committee on Practice Bulletins-Obstetrics. ACOG Practice Bulletin No. 80: premature rupture of the membranes. Clinical management guidelines for obstetrician-gynecologists. Obstet Gynecol 2007;109:1007–19.